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6-Aminocaproic acid

Description References

CAS No. 60-32-2
Chemical Name: 6-Aminocaproic acid
Synonyms: ACS;EACS;EACA;177jd;cy116;Hepin;Amikar;Amicar;CY 116;177 J.D
CBNumber: CB5223888
Molecular Formula: C6H13NO2
Formula Weight: 131.17
MOL File: 60-32-2.mol
6-Aminocaproic acid Property
Melting point : 207-209 °C (dec.)(lit.)
density : 1.03 g/mL at 20 °C
Fp : 207-209°C
storage temp. : 2-8°C
solubility : H2O: 50 mg/mL
form : powder
pka: 4.373(at 25℃)
color : white
PH: 7.0-7.5 (50g/l, H2O, 20℃)
Water Solubility : SOLUBLE
Merck : 14,432
BRN : 906872
CAS DataBase Reference: 60-32-2(CAS DataBase Reference)
NIST Chemistry Reference: Hexanoic acid, 6-amino-(60-32-2)
EPA Substance Registry System: Hexanoic acid, 6-amino-(60-32-2)
SAFETY
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes : Xi
Risk Statements : 36/37/38
Safety Statements : 26-36
WGK Germany : 2
RTECS : MO6300000
TSCA : Yes
HS Code : 29224995
Hazardous Substances Data: 60-32-2(Hazardous Substances Data)
Symbol(GHS):
Signal word: Warning
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H320 Causes eye irritation Serious eye damage/eye irritation Category 2B Warning P264, P305+P351+P338,P337+P313
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
Precautionary statements:
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P264 Wash hands thoroughly after handling.
P264 Wash skin thouroughly after handling.
P304+P340 IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405 Store locked up.

6-Aminocaproic acid Chemical Properties,Usage,Production

Description
6-aminocaproic acid (Brand name: Amicar) is a kind of synthetic derivative of lysine. Since it is a analogue of amino acid lysine, it can act as the inhibitor for enzymes that need to bind to that particular lysine residue, e.g. the proteolytic enzyme such as plasmin, which is responsible for fibrinolysis. Therefore, it has anti-fibrinolytic activity. It also competitively inhibits activation of plasminogen, thereby reducing conversion of plasminogen to plasmin. Based on this property, it can be used for the treatment of acute bleeding due to elevated fibrinolytic activity in many clinical situations. It can also indicated by FDA for the prevention of recurrent hemorrhage in patients of traumatic hyphema. It may also act as a prophylactic against the vascular disease due to its inhibitory effect on the formation of lipoprotein which is the risk factor of vascular disease.
References
https://pubchem.ncbi.nlm.nih.gov/compound/6-aminohexanoic_acid#section=Pharmacology-and-Biochemistry
https://en.wikipedia.org/wiki/Aminocaproic_acid
Chemical Properties
white crystalline powder
Uses
hemostatic
Uses
6-Aminohexanoic Acid is a reagent commonly used for the extraction of aldehydes from reaction mixtures. 6-Aminohexanoic Acid has also been shown to improve solubilization of membrane proteins in elect rophoresis. Studies suggest that 6-Aminohexanoic Acid inhibits the activation of the first component of the complement system.
Uses
Propylparaben Food preservative
Uses
EACA is directly soluble in water at 25 mg/ml. As an inhibitor of plasmin it is has been utilized in the clotting buffer for fibrinogen assays. This buffer is 10 mM potassium and sodium phosphate, pH 6.4, with 0.20 g CaCl2, 5 g 6-Aminohexanoic acid, 1 g sodium azide, and 9 g NaCl in 1 liter. The buffer is stable indefinitely at room temperature.
Definition
ChEBI: An amino-acid anion that is the conjugate base of 6-aminohexanoic acid.
6-Aminocaproic acid Preparation Products And Raw materials
Raw materials
Ammonium hydroxide AMBERLITE IR-120 Caprolactam
Preparation Products
Capobenic acid Gabexate mesylate
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60-32-2(6-Aminocaproic acid)Related Search:
L(+)-Homoarginine hydrochloride DL-PIPECOLIC ACID HYDROCHLORIDE N6-Cbz-L-Lysine 5-HYDROXY-DL-LYSINE HYDROCHLORIDE Ethyl pipecolinate Amstat Ethyl 1-methylpipecolinate AC-LYS-OH 2,6-DIAMINOPIMELIC ACID N-Succinimidyl 4-(N-maleimidomethyl)cyclohexane-1-carboxylate H-LYS(ME)-OH HCL N-EPSILON-ACETYL-L-LYSINE Z-6-AMINOCAPROIC ACID,Z-EPSILON-AMINOCAPROIC ACID,N-BENZYLOXYCARBONYL-6-AMINOCAPROIC ACID,N-CARBOBENZOXY-EPSILON-AMINOCAPROIC ACID,N-CBZ-6-AMINOCAPROIC ACID,N-EPSILON-CARBOBENZOXY-6-AMINOCAPROIC ACID,N-EPSILON-CBZ-EPSILON-AMINOCAPROIC ACID AC-LYS-OME HCL 6-Acetamidohexanoic acid D-Lysine Hexanoic acid 6-Aminocaproic acid
177 J.D 177 J.D. 177j.d. 177jd 6-amino-hexanoicaci Acepramin Acepramine ACS Afibrin Amicar Amikar Aminokapron Atsemin Caplamin Capracid capralense Capramol Capranol Caprocid Caprolisin CL 10304 cl10304 CY 116 cy116 eacakabi EACS e-aminocaproicacid Epsamon Epsicapron Epsikapron Epsilcapramin epsilon S epsilon-Amino-n-hexanoic acid epsilon-leucine epsilon-Norleucine epsilons Hemocaprol Hemopar Hepin kyselinaomega-aminokapronova NSC-26154 omega-Aminohexanoic acid omega-aminohexanoicacid Respramin 蠅-Aminocarboxylic Acids 蠅-Functional Alkanols, Carboxylic Acids, Amines & Halides 60-32-2 6-AMINOCAPROIC ACID 6-AMINOHEXANOIC ACID 6-AMINO-N-HEXANOIC ACID 6-AMINO-N-CAPROIC ACID 6-L-AMINOHEXANOIC ACID AMINOCAPROIC ACID Amino Acids and Peptides Biochemicals and Reagents BioChemical A to C EPSILON-AMINO HEXANOIC ACID
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