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5-AMino-2,4-di-tert-butylphenol

5-AMino-2,4-di-tert-butylphenol structure

CAS No.: 873055-58-4

Chemical Name:: 5-AMino-2,4-di-tert-butylphenol

Synonyms: VX-770 intermediate;4,6-dichloropyridazin-4-ol;2,4-ditert-butyl-5-aminophenol;5-AMino-2,4-di-tert-butylphenol;5-Amino-2,4-ditertiarybutyphenol;5-Amino-2,4-ditertiarybutylphenol;5-Amino-2,4-bis(2-methyl-2-propanyl)phenol;Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)-;2,4-Di-tert-butyl-5-aMinophenyl Methyl carbonate;5-amino-2,4-di-tert-butylphenol hydrochloride (base)

CBNumber:: CB52637683

Molecular Formula:: C14H23NO

Molecular Weight:: 221.34

MDL Number:: MFCD11052607

MOL File:: 873055-58-4.mol

MSDS File:: SDS

Last updated:2024-02-07 14:28:58

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5-AMino-2,4-di-tert-butylphenol Properties

Boiling point	319.7±30.0 °C(Predicted)
Density	0.990±0.06 g/cm3(Predicted)
storage temp.	2-8°C(protect from light)
pka	11.63±0.23(Predicted)
InChI	InChI=1S/C14H23NO/c1-13(2,3)9-7-10(14(4,5)6)12(16)8-11(9)15/h7-8,16H,15H2,1-6H3
InChIKey	BKSDHPHOWDUJNB-UHFFFAOYSA-N
SMILES	C1(O)=CC(N)=C(C(C)(C)C)C=C1C(C)(C)C
FDA UNII	8VR88Q6FAV

SAFETY

Risk and Safety Statements

Symbol(GHS)	GHS07
Signal word	Warning
Hazard statements	H302-H315-H319
Precautionary statements	P261-P305+P351+P338

5-AMino-2,4-di-tert-butylphenol price More Price(12)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
TRC	A604628	5-Amino-2,4-di-tert-butylphenol	873055-58-4	100mg	$295	2021-12-16	Buy
TRC	A604628	5-Amino-2,4-di-tert-butylphenol	873055-58-4	250mg	$605	2021-12-16	Buy
American Custom Chemicals Corporation	CHM0386179	5-AMINO-2,4-DI-TERT-BUTYLPHENOL 95.00%	873055-58-4	5MG	$500.94	2021-12-16	Buy
Chemcia Scientific	CC00-7587	5-Amino-2,4-di-tert-butyl-phenol 95%	873055-58-4	25g	$540	2021-12-16	Buy
Ambeed	A601459	5-Amino-2,4-di-tert-butylphenol 95+%	873055-58-4	100mg	$40	2021-12-16	Buy

Product number	Packaging	Price	Buy
A604628	100mg	$295	Buy
A604628	250mg	$605	Buy
CHM0386179	5MG	$500.94	Buy
CC00-7587	25g	$540	Buy
A601459	100mg	$40	Buy

5-AMino-2,4-di-tert-butylphenol Chemical Properties,Uses,Production

Uses

5-Amino-2,4-di-tert-butylphenol is an intermediate used in the preparation of ivacaftor via condensation of oxo dihydroquinoline carboxylic acid with amino ditert butylphenol.

Synthesis

To a refluxing solution of 2,4-di-tert-butyl-5-nitro-phenol (1.86 g, 7.40 mmol) and ammonium formate (1.86 g) in ethanol (75 mL) was added Pd-5% wt on activated carbon (900 mg). The reaction mixture was stirred at reflux for 2 h, cooled to room temperature, and filtered through Celite. The Celite was washed with methanol, and the combined filtrates were concentrated to yield 5-amino-2,4-di-tert-butyl-phenol as a grey solid (1.66 g, quant.).

5-AMino-2,4-di-tert-butylphenol synthesis

Synthesis of 5-AMino-2,4-di-tert-butylphenol from Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro-

5-AMino-2,4-di-tert-butylphenol Preparation Products And Raw materials

Raw materials

Carbonic acid, 2,4-bis(1,1-diMethylethyl)phenyl Methyl ester Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- 2,4-di-tert-butyl-5-nitrophenyl methyl carbonate 3-ACETAMIDOPHENOL 3-Aminophenol

Carbon 2,4-Di-tert-butylphenol

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Preparation Products

5-AMino-2,4-di-tert-butylphenol Suppliers

Global( 136)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Zhejiang Brunova Technology Co., Ltd.	8617857108485 17857108485	info@zjbrunova.com	China	37	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15932	58
Beijing Cooperate Pharmaceutical Co.,Ltd	010-60279497	sales01@cooperate-pharm.com	CHINA	1811	55
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Biochempartner	0086-13720134139	candy@biochempartner.com	CHINA	967	58
Shenzhen Nexconn Pharmatechs Ltd	+86-755-89396905 +86-15013857715	admin@nexconn.com	China	10248	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58

Supplier	Advantage
Zhejiang Brunova Technology Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Beijing Cooperate Pharmaceutical Co.,Ltd	55
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
career henan chemical co	58
Biochempartner	58
Shenzhen Nexconn Pharmatechs Ltd	58
Chongqing Chemdad Co., Ltd	58

View Lastest Price from 5-AMino-2,4-di-tert-butylphenol manufacturers

Image	Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
	2019-07-06	5-Amino-2,4-di-tert-butylphenol 873055-58-4	US $100.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

5-Amino-2,4-di-tert-butylphenol
873055-58-4
US $100.00 / KG
99%
Career Henan Chemical Co

873055-58-4(5-AMino-2,4-di-tert-butylphenol)Related Search:

2,4-di-tert-butyl-5-nitrophenyl methyl carbonate 4-HYDROXY-QUINOLINE-3-CARBOXYLIC ACID METHYL ESTER Phenol, 2,4-bis(1,1-diMethylethyl)-5-nitro- 2-PHENYLAMINOMETHYLENE-MALONIC ACIDDIETHYL ESTER 4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXYLIC ACID

VX-770

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5-AMino-2,4-di-tert-butylphenol 2,4-Di-tert-butyl-5-aMinophenyl Methyl carbonate Phenol, 5-amino-2,4-bis(1,1-dimethylethyl)- 5-Amino-2,4-bis(2-methyl-2-propanyl)phenol VX-770 intermediate 5-amino-2,4-di-tert-butylphenol hydrochloride (base) 4,6-dichloropyridazin-4-ol 5-Amino-2,4-ditertiarybutyphenol 5-Amino-2,4-ditertiarybutylphenol 2,4-ditert-butyl-5-aminophenol 873055-58-4 973055-58-4