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Acethydrazide

CAS No.
1068-57-1
Chemical Name:
Acethydrazide
Synonyms
ACETOHYDRAZIDE;ACETIC HYDRAZIDE;374;ACETYLHYDRAZINE;Acetyl hydrazide;ACETIC ACID HYDRAZIDE;Acetohydrazid;Acetyl drazide;ENT-61241;NSC 53155
CBNumber:
CB5266159
Molecular Formula:
C2H6N2O
Molecular Weight:
74.08
MDL Number:
MFCD00007610
MOL File:
1068-57-1.mol
MSDS File:
SDS
Last updated:2024-03-21 17:31:59

Acethydrazide Properties

Melting point 58-68 °C (lit.)
Boiling point 129 °C/18 mmHg (lit.)
Density 1.0968 (rough estimate)
refractive index 1.4264 (estimate)
Flash point >230 °F
storage temp. Keep in dark place,Inert atmosphere,2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Moist Crystals and Chunks
pka 13.46±0.18(Predicted)
color White
Water Solubility soluble
Sensitive Hygroscopic
BRN 506165
InChIKey OFLXLNCGODUUOT-UHFFFAOYSA-N
CAS DataBase Reference 1068-57-1(CAS DataBase Reference)
FDA UNII SK0DPC9098
NIST Chemistry Reference Acetic acid, hydrazide(1068-57-1)
EPA Substance Registry System Acetic acid hydrazide (1068-57-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS08
Signal word  Danger
Hazard statements  H301-H315-H319-H341-H351
Precautionary statements  P201-P301+P310+P330-P302+P352-P305+P351+P338
Hazard Codes  Xn,T
Risk Statements  22-36/38-68-40-25
Safety Statements  26-36-45-36/37
RIDADR  1759
WGK Germany  1
RTECS  AI1225000
3-8-10
TSCA  Y
HazardClass  6.1
PackingGroup  II
HS Code  29280090
Toxicity LD50 oral in bird - wild: 42200ug/kg
NFPA 704
2
2 1

Acethydrazide price More Price(33)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich A8309 Acethydrazide 90% 1068-57-1 5g $52.1 2024-03-01 Buy
Sigma-Aldrich A8309 Acethydrazide 90% 1068-57-1 25g $98 2024-03-01 Buy
TCI Chemical A0789 Acetohydrazide >98.0%(GC)(T) 1068-57-1 25g $55 2024-03-01 Buy
TCI Chemical A0789 Acetohydrazide >98.0%(GC)(T) 1068-57-1 100g $136 2024-03-01 Buy
Alfa Aesar A10969 Acetic hydrazide, 96% 1068-57-1 25g $53.65 2024-03-01 Buy
Product number Packaging Price Buy
A8309 5g $52.1 Buy
A8309 25g $98 Buy
A0789 25g $55 Buy
A0789 100g $136 Buy
A10969 25g $53.65 Buy

Acethydrazide Chemical Properties,Uses,Production

Description

Hydrazine, anhydrous appears as a colorless, fuming oily liquid with an ammonia-like odor. Flash point 99°F. Explodes during distillation if traces of air are present. Toxic by inhalation and by skin absorption. Corrosive to tissue. Produces toxic oxides of nitrogen during combustion.

Chemical Properties

White moist crystals and chunks

Uses

Acethydrazide can be used in the synthesis of (E)-N′-(2-hydroxybenzylidene)acetohydrazide, an ONO pincer ligand.

Uses

Acetic hydrazide is used as an antibiotic for the treatment of mycobacterium tuberculosis. It is also involved in the preparation of sunitinib b reacting with 5-fluoroisatin. Further, it inhibits mycolic acid biosynthesis. It serves as an important intermediate in organic synthesis such as nitric furosemide Long (nifuratrone) in medicine.

Uses

Acetohydrazide is a metabolite of Isoniazid (I821450) an antibiotic for treatment of Mycobacterium tuberculosis, inhibits mycolic acid biosynthesis.

Definition

ChEBI: A carbohydrazide that is hydrazine in which one of the hydrogens is replaced by an acetyl group.

Safety Profile

Poison by ingestion, subcutaneous, and intraperitoneal routes. Mutation data reported. Exposure can cause hemolysis and liver damage. See also PHENYLHYDRAZINE. When heated to decomposition it emits toxic fumes of NOX,.

Purification Methods

Acetic hydrazide crystallises as needles from EtOH. It reduces NH3/AgNO3. [Beilstein 2 H 191, 2 IV 435.]

79-20-9
1068-57-1
Synthesis of Acethydrazide from Methyl acetate
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  • Oct 24,2019

View Lastest Price from Acethydrazide manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Acethydrazide pictures 2024-04-19 Acethydrazide
1068-57-1
US $0.00 / kg 1kg 99% 1000mt/year Jinan Finer Chemical Co., Ltd
Acethydrazide pictures 2024-04-12 Acethydrazide
1068-57-1
US $30.00 / kg 1kg 98% 2000kg hebei hongtan Biotechnology Co., Ltd
Acethydrazide pictures 2023-12-26 Acethydrazide
1068-57-1
US $50.00-1.00 / kg 1kg 99 g-kg-tons,free sample is available Henan Fengda Chemical Co., Ltd
  • Acethydrazide pictures
  • Acethydrazide
    1068-57-1
  • US $0.00 / kg
  • 99%
  • Jinan Finer Chemical Co., Ltd
  • Acethydrazide pictures
  • Acethydrazide
    1068-57-1
  • US $30.00 / kg
  • 98%
  • hebei hongtan Biotechnology Co., Ltd
  • Acethydrazide pictures
  • Acethydrazide
    1068-57-1
  • US $50.00-1.00 / kg
  • 99
  • Henan Fengda Chemical Co., Ltd
ACETHYDRAZIDE AKOS 90782 Acethydrazide=Acetylhydrazide ACETHYDRAZIDE 98% acetylhydrazide ,acetohydrazide ,1-hydrazinylpropan-2-one Acetic acid hydrazide, Acetylhydrazine 1-Acetylhydrazine Acethydrazide,95% Acethydrazide,Acetic acid hydrazide, Acetylhydrazine Acethydrazide, 95% 25GR Acethydrazide (moist with methylene chloride) Acethydrazide Synonyms Acetic hydrazide Acetohydrazide for synthesis acetylhydrazide acetyl-hydrazin ENT-61241 Ethanehydrazonic acid ethanehydrazonicacid Hydrazid kyseliny octove hydrazidkyselinyoctove Hydrazine, Acetyl- N-Acetyldiamine NSC 53155 N-ACETYL HYDRAZINE MONOACETYLHYDRAZINE ACETHYDRAZIDE For Synthesis Supply raw material powder CAS No 1068-57-1 Acetyl Hydrazine, the price is favorable Acetic hydrazide, 99%, for synthesis Acetohydrazide> Linezolid Impurity 96 374 Acetyl hydrazide ACETIC ACID HYDRAZIDE ACETOHYDRAZIDE ACETIC HYDRAZIDE Acetohydrazid Acetyl drazide ACETYLHYDRAZINE 1068-57-1 C2H6NO Hydrazides Organic Building Blocks Building Blocks Carbonyl Compounds Aromatic Hydrazides, Hydrazines, Hydrazones and Oximes bc0001 1068-57-1