ChemicalBook >> CAS DataBase List >>(3S,5R)-Rosuvastatin
(3S,5R)-Rosuvastatin
- CAS No.
- 1242184-42-4
- Chemical Name:
- (3S,5R)-Rosuvastatin
- Synonyms
- 5R)-Rosuvastatin;(3S,5R)-Rosuvastatin;Rosuvastatin calcium-8;(3S,5R,6E)-Rosuvastatin;Rosuvastatin Impurity G;Rosuvastatin EP Impurity G;*Buprenorphine Impurity 17;Rosuvastatin impurity G CRS;Rosuvastatin Acid Enantiomer;Rosuvastatin EP Imp G (acid)
- CBNumber:
- CB52706297
- Molecular Formula:
- C22H28FN3O6S
- Molecular Weight:
- 481.54
- MDL Number:
- MFCD28579810
- MOL File:
- 1242184-42-4.mol
- MSDS File:
- SDS
Last updated:2023-05-15 10:43:35
| Boiling point | 745.6±70.0 °C(Predicted) |
|---|---|
| Density | 1.368±0.06 g/cm3(Predicted) |
| solubility | soluble in Methanol, Water |
| pka | 4.25±0.10(Predicted) |
| form | Solid |
| color | Off-White to Pale Yellow |
| Stability | Hygroscopic |
| FDA UNII | GED87J49TB |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302-H315-H319-H335 |
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 |
(3S,5R)-Rosuvastatin Chemical Properties,Uses,Production
Description
Rosuvastatin is an HMG-CoA reductase inhibitor used to lower lipid levels and reduce the risk of cardiovascular disease including myocardial infarction and stroke.
Uses
(3S,5R,6E)-Rosuvastatin is an isomer of Rosuvastatin(R700500), an impurity which acts as a selective, competitive HMG-CoA reductase inhibitor.
Biological Activity
(3S,5R)-Rosuvastatin is the (3S,5R)-enantiomer of Rosuvastatin. Rosuvastatin is a competitive HMG-CoA reductase inhibitor with an IC50 of 11 nM. Rosuvastatin potently blocks human ether-a-go-go related gene (hERG) current with an IC50 of 195 nM. Rosuvastatin reduces the expression of the mature hERG and the interaction of heat shock protein 70 (Hsp70) with the hERG protein. Rosuvastatin is very effective in lowering low-density lipoprotein (LDL) cholesterol, triglycerides, and C-reactive protein levels.
(3S,5R)-Rosuvastatin Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 71)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9352 | 55 |
| Standardpharm Co. Ltd. | 86-714-3992388 | overseasales1@yongstandards.com | United States | 14336 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Antai Fine Chemical Technology Co.,Limited | 18503026267 | info@antaichem.com | CHINA | 9641 | 58 |
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Finetech Industry Limited | +86-27-87465837 +8618971612321 | info@finetechnology-ind.com | China | 9571 | 58 |
| CR Corporation Lomited | fred.wen@crcorporation.cn | CHINA | 12069 | 58 | |
| sgtlifesciences pvt ltd | +8617013299288 | dj@sgtlifesciences.com | China | 12382 | 58 |
View Lastest Price from (3S,5R)-Rosuvastatin manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-10 | Rosuvastatin Calcium Impurity G
1242184-42-4
|
US $0.00-0.00 / mg | 10mg | 90%+ | 10g | Guangzhou PI PI BIOTECH INC |
-
- Rosuvastatin Calcium Impurity G
1242184-42-4
- US $0.00-0.00 / mg
- 90%+
- Guangzhou PI PI BIOTECH INC
1242184-42-4((3S,5R)-Rosuvastatin)Related Search:
Rosuvastatin EP Impurity E (Calcium Salt)
Rosuvastatin EP impurity H
Rosuvastatin ethyl ester
3-Oxo Rosuvastatin SodiuM Salt
4-(4-Fluorophenyl)-6-isopropyl-2-[(N-methyl-n-methylsulfonyl)amino]pyrimidine-5-yl-methanol
tert-Butyl 6-[(1E)-2-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]ethenyl]-2,2-dimethyl-1,3-dioxane-4-acetate
Rosuvastatin methyl ester
N-[4-(4-Fluorophenyl)-6-(1-methylethyl)-5-[(1E)-2-[(2S,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethenyl]-2-pyrimidinyl]-N-methylmethanesulfonamide
Rosuvastatin EP impurity A
Rosuvastatin IsoaMy Ester
1of4
(3S,5R)-Rosuvastatin
(3s,5r,6e)-7-(4-(4-fluorophenyl)-6-(1-methylethyl)-2-(methyl(methylsulfonyl)amino)-5-pyrimidinyl)-3,5-dihydroxy-6-heptenoic acid
Rosuvastatin EP Impurity G
Rosuvastatin (3S,5R) Enantiomer (as diisopropylamine salt)
(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid
Rosuvastatin (3S,5R) enantiomer
(3S,5R,6E)-Rosuvastatin
(3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethylsulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoic acid, calcium salt (2:1)
Rosuvastatin EP Impurity G/ Rosuvastatin Related Compund D (Rosuvastatin Calcium Enantiomer/ enti-Rosuvastatin/ Rosuvastatin (3S,5R)-Isomer)
(3S,5R)-Rosuvastatin CalciumQ: What is
(3S,5R)-Rosuvastatin Calcium Q: What is the CAS Number of
(3S,5R)-Rosuvastatin Calcium Q: What is the storage condition of
(3S,5R)-Rosuvastatin Calcium Q: What are the applications of
(3S,5R)-Rosuvastatin Calcium
Rosuvastatin impurity G (Y0001722)Q: What is
Rosuvastatin impurity G (Y0001722) Q: What is the CAS Number of
Rosuvastatin impurity G (Y0001722)
Rosuvastatin Acid Enantiomer
5R)-Rosuvastatin
Rosuvastatin Calcium EP Impurity G (Calcium Salt)
Rosuvastatin EP impurity G(3S5R)
Rosuvastatin Impurity G
Rosuvastatin EP Imp G (acid)
Rosuvastatin calcium-8
3S,5R-Rosuvastatin calcium salt
Rosuvastatin EP Impurity G (Calcium Salt)
Rosuvastatin impurity G CRS
(3S,5R)-Rosuvastatin Sodium Salt
6-Heptenoic acid, 7-[4-(4-fluorophenyl)-6-(1-methylethyl)-2-[methyl(methylsulfonyl)amino]-5-pyrimidinyl]-3,5-dihydroxy-, (3S,5R,6E)-
Rosuvastatin EP Impurity G / Rosuvastatin Related Compound D / 3S, 5R Rosuvastatin
(3S,5R) Rosuvastatin,(3S,5R)Rosuvastatin
((3S,5R,E)-7-(4-(4-fluorophenyl)-6-isopropyl-2-(N-methylmethyl sulfonamido)pyrimidin-5-yl)-3,5-dihydroxyhept-6-enoate) calcium(II)（Rosuvastatin EP Impurity G）
Rosuvastatin Impurity 11 Monomer(Rosuvastatin EP Impurity G Monomer)
*Buprenorphine Impurity 17
(3S,5R)-7-[4-(4-Fluorophenyl)-6-isopropyl-2-(methyl(methylsulfonyl)amino]pyrimidin-5-yl]-3,5-dihydroxy-6(E)-heptenoic acid calcium salt
1242184-42-4