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Ethyl lactate

CAS No.
97-64-3
Chemical Name:
Ethyl lactate
Synonyms
Ethyl 2-hydroxypropanoate;Actylol;Acytol;Ethyllactat;Ethyl Lactate FCC;ETHYL 2-HYDROXYPROPIONATE;Propanoicacid,2-hydroxy-,ethylester;2-HYDROXYPROPANOIC ACID ETHYL ESTER;Eusolvan;Solactol
CBNumber:
CB5292231
Molecular Formula:
C5H10O3
Molecular Weight:
118.13
MDL Number:
MFCD00065359
MOL File:
97-64-3.mol
MSDS File:
SDS
Last updated:2023-12-15 09:32:12

Ethyl lactate Properties

Melting point -26°C
alpha D14 -10°
Boiling point 154 °C (lit.)
Density 1.031 g/mL at 25 °C (lit.)
vapor pressure 81hPa at 20℃
FEMA 2440 | ETHYL LACTATE
refractive index 1.4124
Flash point 54.6±6.4 °C
solubility Miscible with water (with partial decomposition), ethanol (95%), ether, chloroform, ketones, esters, and hydrocarbons.
pka 13.21±0.20(Predicted)
form clear liquid
color Colorless
Odor Mild characteristic.
optical activity [α]20/D 10.5°, neat
Odor Type fruity
Water Solubility 100g/L at 20℃
JECFA Number 931
Merck 14,3817
Dielectric constant 13.1(25℃)
Stability Stable. Combustible. Incompatible with strong oxidizing agents.
InChIKey LZCLXQDLBQLTDK-UHFFFAOYSA-N
LogP 0.7 at 25℃
Substances Added to Food (formerly EAFUS) ETHYL LACTATE
FDA 21 CFR 172.515; 175.105; 73.1001
CAS DataBase Reference 97-64-3(CAS DataBase Reference)
EWG's Food Scores 1-4
FDA UNII F3P750VW8I
NIST Chemistry Reference Propanoic acid, 2-hydroxy-, ethyl ester(97-64-3)
EPA Substance Registry System Ethyl lactate (97-64-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS05,GHS07
Signal word  Danger
Hazard statements  H226-H315-H318-H335
Precautionary statements  P210-P233-P240-P280-P303+P361+P353-P305+P351+P338
Hazard Codes  Xi
Risk Statements  10-37-41
Safety Statements  24-26-39
RIDADR  1192
WGK Germany  1
RTECS  OD5075000
HazardClass  3.2
PackingGroup  III
HS Code  29181100
NFPA 704
2
3 0

Ethyl lactate price More Price(15)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich W244015 Ethyl Lactate natural, ≥98%, FCC, FG 97-64-3 1kg $98.6 2024-03-01 Buy
Sigma-Aldrich W244015 Ethyl Lactate natural, ≥98%, FCC, FG 97-64-3 5kg $449 2024-03-01 Buy
Sigma-Aldrich W244015 Ethyl Lactate natural, ≥98%, FCC, FG 97-64-3 10Kg $501 2024-03-01 Buy
Sigma-Aldrich W244007 Ethyl Lactate ≥98%, FCC, FG 97-64-3 sample-k $54.6 2024-03-01 Buy
Sigma-Aldrich W244007 Ethyl Lactate ≥98%, FCC, FG 97-64-3 1kg $76.5 2024-03-01 Buy
Product number Packaging Price Buy
W244015 1kg $98.6 Buy
W244015 5kg $449 Buy
W244015 10Kg $501 Buy
W244007 sample-k $54.6 Buy
W244007 1kg $76.5 Buy

Ethyl lactate Chemical Properties,Uses,Production

Description

Ethyl lactate, an ester of lactic acid, is a "green" solvent derived from processing corn. Lactate esters solvents are commonly used solvents in the paints and coatings industry and have numerous attractive advantages including being 100% biodegradable, easy to recycle, noncorrosive, noncarcinogenic, and nonozone depleting.
Ethyl lactate is an important organic ester, which is biodegradable and can be used as food additive, in perfumery, as flavour chemicals and solvent, which can dissolve acetic acid cellulose and many resins (Tanaka et al., 2002). It is a particularly attractive solvent for the coatings industry as a result of its high solvency power, high boiling point, low vapour pressure and low surface tension. Ethyl lactate is a desirable coating for wood, polystyrene and metals and also acts as a very effective paint stripper and graffiti remover. It has replaced solvents including N-methyl Pyrrolidone (NMP) (Reisch, 2008), toluene, acetone and xylene, which has resulted in the workplace being made a great deal safer.
ethyl lactate structure
ethyl lactate structure

Chemical properties

Ethyl lactate appears as colorless to light yellow transparent liquid with rum, fruit and cream aroma. The freezing point:-25°C; the boiling point: 154°C, specific rotation [a] 14d:-10°. It is easily soluble in ethanol, acetone, ether, esters and other organic solvents; there is some degree of hydrolysis upon being miscible with water. Mouse oral LD50: 2.5g/kg, ADI is subject to no special provisions (FAO/WHO, 1994).
Ethyl lactate
Ethyl lactate is a common solvent in pharmaceutical, cosmetic, detergent, coatings, food and fragrance production. It is considered biodegradable in its natural form and it is exempt from many restrictions imposed in accordance with the disposal of chemicals. For this reason it is a highly desirable product in a “green”, environmentally conscious industry. In the presence of water, acids and bases the chemical will hydrolyse into ethanol and lactic acid.

Uses

Ethyl Lactate is a solvent manufactured from l (+) lactic acid which is miscible in water and most organic solvents and is cleared for use as a flavoring agent. it is a naturally occurring constituent of california and spanish sherries. it is a clear, colorless, nontoxic liquid of low volatility, having a ph of 7–7.5. it is used as a food and beverage flavoring agent.Ethyl lactate is used in the electronics industry to remove salts and fat from circuit boards; it is also a component in paint strippers.

Production method

Ethyl lactate is usually produced by the esterification of lactic acid with ethanol using sulfuric acid catalyst.

Usage limit

FEMA (mg/mL): Soften drink: 5.4; Cold drinks: 17; Candies 28; baked goods 71; pudding class 8.3; gums 580 to 3100; alcohol 1000; syrup 35.
Take moderate as limit (FDA § 172.515, 2000).

Toxicity

ADI is not subject to specific special provisions (FAO/WHO, 1994).
GRAS (FEMA).
LD50 2500 mg/kg (mouse, oral).

Chemical Properties

Ethyl Lactate is a colorless liquid with a light ethereal, buttery odor. It miscible in water, alcohols, ketones , esters, hydrocarbons, ether and oil. The odor threshold is reported to be 0.89 mg/m3 and the odor nuisance threshold to be 65 mg/m3.

Occurrence

Ethyl lactate is reported to be found in apple, citrus fruits, pineapple, peas, sauerkraut, vinegar, bread, beer, grape brandy, rum, whisky, cider, sherry, wine, cocoa, banty beer, plum brandy and pear brandy. It has been approved by the US FDA for food use.

Uses

Ethyl lactate is used as a solvent for nitrocellulose, cellulose acetate, and many cellulose ethers and resins. It is also used in lacquers, paints, enamels, varnishes, stencil sheets, safety glass and flavoring. Ethyl lactate is furthermore used in some cosmetic formulations in soaps, detergents, creams and lotions with a maximum concentration of 0.2 %. In recent years it has been used as degreaser as a substitute for trichloroethylene.

Definition

ChEBI: Ethyl 2-hydroxypropanoate is the ethyl ester obtained of 2-hydroxypropanoic acid. It has a role as a metabolite. It is a secondary alcohol, a lactate ester and an ethyl ester. It is functionally related to a 2-hydroxypropanoic acid.

Preparation

Ethyl lactate is produced by the esterification of lactic acid with ethanol in the presence of a little mineral oil, or by combination of acetaldehyde with hydrocyanic acid to form acetaldehyde cyanhydrin. This is followed by treatment with ethanol (95%) and hydrochloric or sulfuric acid. Purification is achieved using fractional distillation. The commercial product is a racemic mixture.

Synthesis Reference(s)

Synthetic Communications, 19, p. 1335, 1989 DOI: 10.1080/00397918908054542

General Description

A clear colorless liquid with a mild odor. Flash point 115°F. Denser than water and soluble in water. Vapors heavier than air.

Air & Water Reactions

Flammable. Soluble in water.

Reactivity Profile

Ethyl lactate is an ester. Esters react with acids to liberate heat along with alcohols and acids. Strong oxidizing acids may cause a vigorous reaction that is sufficiently exothermic to ignite the reaction products. Heat is also generated by the interaction of esters with caustic solutions. Flammable hydrogen is generated by mixing esters with alkali metals and hydrides.

Health Hazard

Inhalation of concentrated vapor may cause drowsiness. Contact with liquid causes mild irritation of eyes and (on prolonged contact) skin. Ingestion may cause narcosis.

Fire Hazard

HIGHLY FLAMMABLE: Will be easily ignited by heat, sparks or flames. Vapors may form explosive mixtures with air. Vapors may travel to source of ignition and flash back. Most vapors are heavier than air. They will spread along ground and collect in low or confined areas (sewers, basements, tanks). Vapor explosion hazard indoors, outdoors or in sewers. Runoff to sewer may create fire or explosion hazard. Containers may explode when heated. Many liquids are lighter than water.

Safety

Ethyl lactate is used as a flavoring agent in pharmaceutical preparations, and is found in food products. The estimated acceptable daily intake for lactic acid is 12.5 mg/kg body-weight.
In general, lactate esters have an oral LD50 > 2000 mg/kg; and the inhalation LC50 is generally above 5000 mg/m3. They have the potential of causing eye and skin irritation (on prolonged contact), but not sensitization. Ethyl lactate is moderately toxic by intraperitoneal, subcutaneous, and intravenous routes. There is low oral and skin contact toxicity; although ingestion may cause nausea, stomach and throat pain, and narcosis. Inhalation of concentrated vapor of ethyl lactate may cause irritation of the mucous membranes, drowsiness, and narcosis.
LD50 (rat, oral): >5.0 g/kg
LD50 (mouse, oral): 2.5 g/kg
LD50 (mouse, SC): 2.5 g/kg
LD50 (mouse, IV): 0.6 g/kg
LD50 (rabbit, skin): >5.0 g/kg

Veterinary Drugs and Treatments

Ethyl lactate shampoo can be used when an antibacterial shampoo (bacteriostatic and bactericidal) is needed particularly in animals with surface and superficial pyodermas that cannot tolerate benzoyl peroxide. It also has keratoplastic effect, which provides anti-seborrheic activity.
A lipid soluble compound, ethyl lactate penetrates hair follicles and sebaceous glands where bacterial lipases convert it into lactic acid and ethanol, which are responsible for its antibacterial action. It is not as active as benzoyl peroxide against staphylococcal organisms, but is less irritating and drying.

storage

Stable at normal temperature and pressure. Ethyl lactate is a flammable liquid and vapor. Store in a cool, dry, and well-ventilated location away from any fire hazard area, in a tightly closed container.

Incompatibilities

Incompatible with bases or strong alkalis and may cause fire or explosion with strong oxidizing agents.

Regulatory Status

GRAS listed. Reported in the EPA TSCA Inventory.

Global( 426)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Bojing Chemical Co.,Ltd.
+86-86-02137122233 +8613795318958 bj1@bj-chem.com China 298 55
Henan Xiangduo Industry Co., Ltd.
+86-15981848961 +86-15981848961 sales@xiangduochem.com China 497 58
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12452 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2504 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Shanghai Time Chemicals CO., Ltd.
+86-021-57951555 +8617317452075 jack.li@time-chemicals.com China 1807 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9353 55
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View Lastest Price from Ethyl lactate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Ethyl lactate pictures 2023-07-29 Ethyl lactate
97-64-3
US $100.00 / kg 1kg 99% 500t/month Henan Bao Enluo International TradeCo.,LTD
Ethyl lactate pictures 2023-07-27 Ethyl lactate
97-64-3
US $1.50 / g 1g 99.0% Min 100 Tons Shaanxi Didu New Materials Co. Ltd
Ethyl lactate pictures 2023-06-30 Ethyl lactate
97-64-3
US $0.00 / KG 1KG 99% 50000KG/month Hebei Mojin Biotechnology Co., Ltd
  • Ethyl lactate pictures
  • Ethyl lactate
    97-64-3
  • US $100.00 / kg
  • 99%
  • Henan Bao Enluo International TradeCo.,LTD
  • Ethyl lactate pictures
  • Ethyl lactate
    97-64-3
  • US $1.50 / g
  • 99.0% Min
  • Shaanxi Didu New Materials Co. Ltd
  • Ethyl lactate pictures
  • Ethyl lactate
    97-64-3
  • US $0.00 / KG
  • 99%
  • Hebei Mojin Biotechnology Co., Ltd
ETHYL LACTATE NATURAL FCC ETHYL LACTATE SOLVENT GRADE Ethyl α-hydroxypropanoate DL-Ethyl  Ethyl rac-lactate Purasolv ELS 2-Hydroxypropionic acid ethyl Lactic acid ethyl Ethyl-2-hydrxypropionate EthyI lactate yl lactate Ethyl 2-Hydroxypropionate 2-Hydroxypropionic Acid Ethyl Ester Lactic Acid Ethyl Ester Ethyl LaCLate Ethyl Lactate, 97.0%(GC) 2-Hydroxypropionic Acid Ethyl Ester Ethyl 2-Hydroxypropionate Lactic Acid Ethyl Ester 1-hydroxyethanecarboxylicacid,ethylester 2-hydroxy-propanoicaciethylester Ethyl alpha-hydroxypropionate Ethyl ester of lactic acid ethyl-2-hydroxypropanoate ethylalpha-hydroxypropionate Ethylester kyseliny mlecne ethylesterkyselinymlecne Eusolvan Lactate d'ethyle lactated’ethyle lactated’ethyle[french] Solactol ETHYL LACTATE SUPRA ETHYL LACTATE GC STANDARD EthylLactate,Certified. Propanoic acid, 2-hydroxy-, ethyl ester (9CI) EthylL-lactate,99% LACTIC ACID ETHYL ESTER ETHYL A-HYDROXYPROPIONATE ETHYL HYDROXY PROPIONATE ETHYL LACTATE Ethyl lactate 98+ FEMA 2440 ETHYL-2-HYDROXYPROPANATE 2-HYDROXYPROPIONIC ACID ETHYL ESTER ethyllactate,2-hydroxy-propanoicacidethylester ETHYL LACTATE ELECTRONIC GRADE 2-[[4-(phenylmethyl)-1-piperazinyl]methyl]isoindole-1,3-dione Natural Ethyl Lactate excel grade ethyl lactate hot sale ethyl lactate CAS No.: 97-64-3 Ethyl-DL-lactate DL-Ethyl Lactate EthylLactate> Ethyl lactate USP/EP/BP Ethyl lactate(kosher) Ethyl Lactate, 98&plus ETHYL LACTATE For Synthesis Actylol Acytol Ethyl 2-hydroxypropanoate Propanoicacid,2-hydroxy-,ethylester