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Bis(trimethylsilyl)trifluoroacetamide

Bis(trimethylsilyl)trifluoroacetamide structure

CAS No.: 25561-30-2

Chemical Name:: Bis(trimethylsilyl)trifluoroacetamide

Synonyms: BSTFA;N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE;Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate;N,O-BSTFA;N,O-Bis(Trimethylsilyl);N.O-Bis(trimethylsilyl)trifluoro acetamide (BSTFA);n,o-bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane;N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 1% TMCS, ampuled under argon;bstfa kit;REGISIL RC-1

CBNumber:: CB5464744

Molecular Formula:: C8H18F3NOSi2

Molecular Weight:: 257.4

MDL Number:: MFCD00008269

MOL File:: 25561-30-2.mol

MSDS File:: SDS

Last updated:2024-04-08 17:36:13

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Bis(trimethylsilyl)trifluoroacetamide Properties

Melting point	-10°C
Boiling point	45-50 °C14 mm Hg(lit.)
Density	0.97 g/mL(lit.)
refractive index	n20/D 1.384(lit.)
Flash point	75 °C
storage temp.	2-8°C
solubility	Miscible with chloroform.
form	Liquid
pka	1.82±0.50(Predicted)
Specific Gravity	0.971
color	Colorless to pale yellow
Water Solubility	hydrolyses
Hydrolytic Sensitivity	8: reacts rapidly with moisture, water, protic solvents
Sensitive	Moisture Sensitive
BRN	3607620
Stability	Moisture Sensitive
InChIKey	XCOBLONWWXQEBS-KPKJPENVSA-N
CAS DataBase Reference	25561-30-2(CAS DataBase Reference)
FDA UNII	5T8NA426KZ
NIST Chemistry Reference	Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS05,GHS07

Signal word

Danger

Hazard statements

H225-H302-H314

Precautionary statements

P210-P233-P280-P301+P312-P303+P361+P353-P305+P351+P338

Hazard Codes

C,F,T

Risk Statements

11-34-10-35-14

Safety Statements

26-36/37/39-45-16

RIDADR

UN 2924 3/PG 3

WGK Germany

10-21

Hazard Note

Flammable/Moisture Sensitive

TSCA

Yes

HazardClass

PackingGroup

III

HS Code

29310095

NFPA 704

	3
3		1

Bis(trimethylsilyl)trifluoroacetamide price More Price(80)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	B-023	BSTFA (with 1% TMCS) kit of 10 × 1?mL, analytical standard, Cerilliant?	25561-30-2	10x1mL	$98.3	2024-03-01	Buy
Sigma-Aldrich	15222	N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0%	25561-30-2	1mL	$30.5	2024-03-01	Buy
Sigma-Aldrich	15222	N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0%	25561-30-2	5ml	$78.6	2024-03-01	Buy
Sigma-Aldrich	15222	N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0%	25561-30-2	25mL	$195	2024-03-01	Buy
Sigma-Aldrich	15222	N,O-Bis(trimethylsilyl)trifluoroacetamide for GC derivatization, LiChropur?, ≥99.0%	25561-30-2	10x1mL	$286	2024-03-01	Buy

Product number	Packaging	Price	Buy
B-023	10x1mL	$98.3	Buy
15222	1mL	$30.5	Buy
15222	5ml	$78.6	Buy
15222	25mL	$195	Buy
15222	10x1mL	$286	Buy

Bis(trimethylsilyl)trifluoroacetamide Chemical Properties,Uses,Production

Uses

Used for synthesis of pharmaceutical intermediates.

Chemical Properties

Clear to yellowish clear liquid

Uses

Used as a reactant in the preparation of pyrimidinone ribosides and analogs that show anti-tumor properties.

Uses

N,O-bis(trimethylsilyl)-trifluoroacetamide (BSTFA) is similar to BSA in specificity of modification and there are several studies which have used both reagents.One study found BSTFA superior to BSA in product stability and yield of derivative. Another study compared several trimethylsilyl donors for end-capping of silica and observed that BSTFA was more reactive than BSA but less reactive than TMCim. Both BSA and BSTFA were used to prepare trimethylsilyl derivatives of pyrimidines and purines.Current work has used BSTFA for metabolomics analysis of urine,for the measurement of khatamines (psychoactive amines of khat (Catha edulis Forsk), and for the measurement of acrylamide in cocoa.

Uses

N,O-Bis(trimethylsilyl)trifluoroacetamide is used for analytical purposes or as a chemical reagent for synthesis of more complex molecules. It is silylation reagent useful in GC and GC-MS for the derivatization of a wide range of functional groups under mild conditions. It is also used as DAT inhibitor and a SLC6A2 inhibitor. It is routinely used to derivatize carboxylic acids, phenols, steroids, amines, alcohols, and alkaloids and amides.

Definition

ChEBI: A silyl ether that is the N,O-bis(trimethylsilyl) derivative of trifluoroacetamide. N,O-bis(trimethylsilyl)trifluoroacetamide is a derivatisation agent used in gas chromatography/m ss spectrometry applications.

General Description

N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane has found application to be used in gas chromatography (GC) and mass-spectrometry (MS). It can also be used in HPLC- electrochemical detection assay of 8-oxo-deoxyguanosine and?8-oxo-guanine.

Bis(trimethylsilyl)trifluoroacetamide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(Trimethylsilyl)-2-[(trimethylsilyl)oxy]pyrimidin-4-amine 2-(Trimethylsiloxy)-1,3-butadiene β-D-Glucopyranose, 1,6-anhydro-2,3,4-tris-O-(trimethylsilyl)-

Bis(trimethylsilyl)trifluoroacetamide Suppliers

Global( 520)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7786	58
airuikechemical co., ltd.	+undefined86-15315557071	sales02@airuikechemical.com	China	994	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1290	60
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Zjartschem	+86-571-8723 8903 jocelynpan@zjarts.com	jocelynpan@zjarts.com	CHINA	993	58
Tianjin Zhongxin Chemtech Co., Ltd.	+86-022-66880623 +8618622897568	sales@tjzxchem.com	China	559	58
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58

Supplier	Advantage
Henan Fengda Chemical Co., Ltd	58
airuikechemical co., ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
ATK CHEMICAL COMPANY LIMITED	60
Zjartschem	58
Tianjin Zhongxin Chemtech Co., Ltd.	58
career henan chemical co	58

View Lastest Price from Bis(trimethylsilyl)trifluoroacetamide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-08	bis(trimethylsilyl)trifluoroacetamide 25561-30-2	US $0.00-0.00 / Kg	1Kg	99.9%	200tons	airuikechemical co., ltd.
2024-01-22	bis(trimethylsilyl)trifluoroacetamide 25561-30-2	US $8.00-0.80 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2023-03-01	Bis(trimethylsilyl)trifluoroacetamide 25561-30-2	US $60.00 / kg	1kg	99%	100 tons	Hebei Duling International Trade Co. LTD

bis(trimethylsilyl)trifluoroacetamide
25561-30-2
US $0.00-0.00 / Kg
99.9%
airuikechemical co., ltd.

bis(trimethylsilyl)trifluoroacetamide
25561-30-2
US $8.00-0.80 / KG
99%
Henan Fengda Chemical Co., Ltd

Bis(trimethylsilyl)trifluoroacetamide
25561-30-2
US $60.00 / kg
99%
Hebei Duling International Trade Co. LTD

Bis(trimethylsilyl)trifluoroacetamide Spectrum

Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)MS Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)¹HNMR Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)IR1 Bis(trimethylsilyl)trifluoroacetamide(25561-30-2)Raman

25561-30-2(Bis(trimethylsilyl)trifluoroacetamide)Related Search:

Trifluoroacetamide TRIMETHYLSILANE Azidotrimethylsilane Methyltris(methylethylketoxime)silane Iodotrimethylsilane

N-6-Trifluoroacetyl-L-lysine Methyltriethoxysilane Acetamide N,O-Bis(trimethylsilyl)acetamide Hexamethyldisilane

N-(Trimethylsilyl)acetamide Trifluoroacetamidine tert-Butyldimethylsilyl chloride Methyltrichlorosilane Dichlorodimethylsilane

Bis-(9,9-diMethyl-9H-fluoren-2-yl)-aMine N,N'-Dimethyl-1,2-ethanediamine N,N-Bis(2-cyanoethyl)formamide

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BSTFA containing 1% TMCS N,O-Bis(trimethylsily)trifluoroamide N,O-bis(trimethylsilyl)acetamide,*with 10% N,O-Bis(trimethylsilyl)trifluoroacetamide, contains 10% TMCS Bis(trimethylsilyl)trifluoroacetamide for gas chromatography Acetamide, 2,2,2-trifluoro-O,N-bis(trimethylsilyl)- Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester N,O-bis(trimehylsilyl)trifluoroacetamide bis(Trifluoromethylsilyl)trifluoroacetamide BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE, 9 9+%, DERIVATIZATION GRADE BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE*(B STFA) BULK BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE, 9 9+% N,O-BIS-(TRIMETHYLSILYL)-TRIFLUOR-ACETAM ID, PURISS.>99% (GC) N,O-BIS(TRIMETHYLSILYL)TRIFLUORO-ACETAMI DE, FOR GC BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE*(B STFA) WITH BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE*(B STFA) SEALE N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE WITH TRIMETHYLCHLOROSILANE, 98% (EXCLUDING TMCS) BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE, 9 9%, WITH 1% TMCS N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACET-AMI DE, PGE 10 X 1 ML N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACET-AMI DE WITH 1% TMCS N,O-BIS(TRIMETHYLSILYL)TRIFLUOROACET-AMI DE 1% TMCS 10X1ML BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE 99% WITH 1%TMCS PACKAGED UNDER ARGON IN RESEALABLE CHEMSEAL– BOTTLES N,O-BIS(TRIMETHYLSILYL) TRIFLUOROACETAMIDE 98+% N.O-Bis(Trimethylsilyl)Trifluoroacetamide(Bstfa),Finasteride N,O-Bis(trimethylsilyl)trifluoroacetamide, 98+% , BSTFA BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE WITH 10%TMCS BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE(BSTFA) N,O-Bis(trimethylsilyl)trifluoroacetamide99+% N,O-Bis(trimethylsilyl)trifluoroacetamide, packaged in 1 ml ampules, 98% N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% trimethylsilyl chloride N,0-Bis(trimethylsilyl)trifluoroacetamideBSTFA bstfa + tmcs bstfa kit 2,2,2-Trifluoro-1-trimethylsiloxy-N-trimethylsilylethanimine 2,2,2-Trifluoro-N-(trimethylsilyl)acetimidic acid trimethylsilyl ester 2,2,2-Trifluoro-N-(trimethylsilyl)ethanimidic acid trimethylsilyl ester N-(Trimethylsilyl)-1-(trimethylsilyloxy)-2,2,2-trifluoroethanimine N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal^t bottles N,O-Bis(trimethylsilyl)trifluoroacetamide, with 1% TMCS, packaged under Argon in resealable ChemSeal N,O-Bis(trimethylsilyl)trifluoroacetamide, 99+%, packaged under Argon in resealable ChemSeal^t bottl BSTFA-TMCS (99:1) [Derivatizing Reagent for GC] BSTFA [=N,O-Bis(trimethylsilyl)trifluoroacetamide] N,O-Bis(trimethylsilyl)trifluoroacetamide ,97.5% N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane,BSTFA + TMCS, Silylating mixture Fluka V N,O-Bis(trimethylsilyl)trifluoroacetamide with trimethylchlorosilane,BSTFA + TMCS BSTFA (with 1% TMCS), 10 amps. N,O-Bis(trimethylsilyl)trifluoroacetamide, packaged in 1 ml ampoules, 98% N,O-Bis(trimethylsilyl)trifluoroacetamide derivatization grade N,O-Bis(trimethylsilyl)trifluoroacetamide, 99+%, packaged under Argon in resealable ChemSeal^t bottles BSTFA (with 1% TMCS) Trimethylsilyl (1Z)-2,2,2-trifluoro-N-[(Z)-trimethylsilyl]ethanimidoate LABOTEST-BB LT00453960 BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE BIS(TRIMETHYL)TRIFLUOROACETAMIDE N,N-BIS(TRIMETHYLSILYL)TRIFLUOROACETAMIDE SILYLATING MIXTURE FLUKA V REGISIL RC-1 REGISIL RC-2