CP-424,174

CP-424,174 structure

CAS No.: 210825-31-3

Chemical Name:: CP-424,174

Synonyms: CP-424,174;CP-424,174 >=98% (HPLC);N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide;CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR);N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide;Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)-

CBNumber:: CB54741315

Molecular Formula:: C22H29ClN2O4S

Molecular Weight:: 452.99

MDL Number:: MFCD30537538

MOL File:: 210825-31-3.mol

MSDS File:: SDS

Last updated:2023-05-18 11:31:09

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CP-424,174 Properties

Density	1?+-.0.06 g/cm3(Predicted)
storage temp.	room temp
solubility	DMF: 30 mg/ml,DMSO: 30 mg/ml,Ethanol: 30 mg/ml,Ethanol:PBS (pH 7.2) (1:5): 0.16 mg/ml
pka	4.67±0.10(Predicted)
form	powder
color	white to beige

CP-424,174 price More Price(6)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PZ0347	CP-424,174 ≥98% (HPLC)	210825-31-3	5mg	$114	2024-03-01	Buy
Sigma-Aldrich	PZ0347	CP-424,174 ≥98% (HPLC)	210825-31-3	25mg	$464	2024-03-01	Buy
Tocris	6107	CP424174 ≥98%(HPLC)	210825-31-3	10	$117	2021-12-16	Buy
Tocris	6107	CP424174 ≥98%(HPLC)	210825-31-3	50	$393	2021-12-16	Buy
TRC	C781493	CP424174	210825-31-3	1mg	$75	2021-12-16	Buy

Product number	Packaging	Price	Buy
PZ0347	5mg	$114	Buy
PZ0347	25mg	$464	Buy
6107	10	$117	Buy
6107	50	$393	Buy
C781493	1mg	$75	Buy

CP-424,174 Chemical Properties,Uses,Production

Biochem/physiol Actions

CP-424,174 is a cytokine release inhibitory drugs (CRID) that inhibits the post-translational processing and secretion of IL-1b in response to LPS and ATP in human monocytes. It is quite possible that similarly to CP-456,773 (termed CRID3), CP-424,174 inhibits both NLRP3 and AIM2 inflammasomes by preventing ASC oligomerisation.

CP-424,174 Preparation Products And Raw materials

Raw materials

Preparation Products

CP-424,174 Suppliers

Global( 28)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32686	60
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Wuhan Topule Biopharmaceutical Co., Ltd	+8618327326525	masar@topule.com	China	8474	58
Aladdin Scientific	+1-833-552-7181	sales@aladdinsci.com	United States	57511	58
Sigma-Aldrich	021-61415566 800-8193336	orderCN@merckgroup.com	China	51471	80
Zhengzhou Alfachem Co.,Ltd.	0371-53778726 18003825608	liuxiaoyan@alfachem.cn	China	1951	58
Shanghai Rechem science Co., Ltd.	21-31433387 15618786686	sales@rechemscience.com	China	2991	58
Shanghai Chaolan Chemical Technology Center	QQ:65489617 15618227136	info@SuperLan-chem.com	China	9756	58
Shanghai SuperLan Chemcial Technique Centre	021-2022843681 15618226720	chaolaichem@foxmail.com	China	9038	58
Shanghai Hongye Biotechnology Co. Ltd	400-9205774	sales@glpbio.cn	China	6870	58

Supplier	Advantage
ATK CHEMICAL COMPANY LIMITED	60
TargetMol Chemicals Inc.	58
Wuhan Topule Biopharmaceutical Co., Ltd	58
Aladdin Scientific	58
Sigma-Aldrich	80
Zhengzhou Alfachem Co.,Ltd.	58
Shanghai Rechem science Co., Ltd.	58
Shanghai Chaolan Chemical Technology Center	58
Shanghai SuperLan Chemcial Technique Centre	58
Shanghai Hongye Biotechnology Co. Ltd	58

CP-424,174 N-[[[4-Chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)benzenesulfonamide Benzenesulfonamide, N-[[[4-chloro-2,6-bis(1-methylethyl)phenyl]amino]carbonyl]-3-(1-hydroxy-1-methylethyl)- CP-424,174 >=98% (HPLC) N-((4-Chloro-2,6-diisopropylphenyl)carbamoyl)-3-(2-hydroxypropan-2-yl)benzenesulfonamide CP424174,IL-1β,NLRP3,Inhibitor,CP 424174,CP-424174,Inflammasome,inhibit,NOD-like Receptor (NLR) 210825-31-3