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Sennoside A

CAS No.
81-27-6
Chemical Name:
Sennoside A
Synonyms
Pursenni;SENNOSIDA;Glysennid;SENNOSIDE;PURSENNID;Nsc 112929;GLYSENNIDE;PURSENNIDE;SENNOSIDE A;Sennoside A1
CBNumber:
CB5663235
Molecular Formula:
C42H38O20
Molecular Weight:
862.74
MDL Number:
MFCD00151527
MOL File:
81-27-6.mol
MSDS File:
SDS
Last updated:2024-04-12 23:00:59

Sennoside A Properties

Melting point >191oC (dec.)
alpha D20 -164° (c = 0.1 in 60% acetone); D20 -147° (c = 0.1 in 70% acetone); D20 -24° (c = 0.2 in 70% dioxane)
Boiling point 1144.8±65.0 °C(Predicted)
Density 1.743±0.06 g/cm3(Predicted)
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Aqueous Base (Slightly, Heated), DMSO (Slightly, Heated)
pka 3.31±0.40(Predicted)
color Yellow to Dark Yellow
BRN 5723746
Stability Hygroscopic
InChIKey IPQVTOJGNYVQEO-KGFNBKMBSA-N
LogP 1.880 (est)
FDA 21 CFR 156.145
FDA UNII 2F1O30GVXH

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P501
Risk Statements  22
Safety Statements  22-45
WGK Germany  3
3-10
HS Code  29173990
NFPA 704
0
2 0

Sennoside A price More Price(44)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 68909 Sennoside A analytical standard 81-27-6 5mg $144 2024-03-01 Buy
Sigma-Aldrich PHL89276 Sennoside A phyproof? Reference Substance 81-27-6 20MG $454 2024-03-01 Buy
Sigma-Aldrich 68909 Sennoside A analytical standard 81-27-6 25mg $544 2024-03-01 Buy
Sigma-Aldrich 1612018 Sennoside A United States Pharmacopeia (USP) Reference Standard 81-27-6 20mg $577 2024-03-01 Buy
Sigma-Aldrich 01870575 Sennoside A primary reference standard 81-27-6 25MG $606 2023-06-20 Buy
Product number Packaging Price Buy
68909 5mg $144 Buy
PHL89276 20MG $454 Buy
68909 25mg $544 Buy
1612018 20mg $577 Buy
01870575 25MG $606 Buy

Sennoside A Chemical Properties,Uses,Production

Chemical Properties

Light yellow powder

Uses

a natural anthroquinonone glucoside calcium complex with laxative properties

Uses

Sennoside A is used as a laxative in the treatment of constipation. In addition. it is hypothesized to induce cell proliferation and may be a potential carcinogenic agent.

Definition

ChEBI: Sennoside A is a member of the class of sennosides that is rel-(9R,9'R)-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid which is substituted by hydroxy groups at positions 4 and 4', by beta-D-glucopyranosyloxy groups at positions 5 and 5', and by oxo groups at positions 10 and 10'. The exact stereochemisty at positions 9 and 9' is not known - it may be R,R (as shown) or S,S. It is a member of sennosides and an oxo dicarboxylic acid.

Purification Methods

Sennoside A (bianthraquinonyl-bis-glucoside R,R-enantiomer) [81-27-6] M 862.7, m 220 -2 4 0o(dec), [ ] D -164o (c 0.1, Me2CO/H2O 6:4), [ ] D -24o (c 0.2, 70% aqueous dioxane). Sennoside A forms yellow crystals from aqueous acetone, 2-ethoxyethanol or large volumes of H2O. [Stoll et al. Helv Chim Acta 32 1896 1900, Beilstein 17 III/IV 3403.]

Sennoside A Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 297)Suppliers
Supplier Tel Email Country ProdList Advantage
Chengdu Biopurify Phytochemicals Ltd.
+8618080483897 sales@biopurify.com China 3424 58
Wuhan Haorong Biotechnology Co.,ltd
+8618565342920 sales@chembj.net China 269 58
BINBO BIOLOGICAL CO.,LTD
+8618629063126 info@binbobiological.com China 215 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9353 55
Shanghai Zheyan Biotech Co., Ltd.
18017610038 zheyansh@163.com CHINA 3620 58
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Shaanxi Pioneer Biotech Co., Ltd .
+8613259417953 sales@pioneerbiotech.com China 3000 58
Hubei xin bonus chemical co. LTD
86-13657291602 linda@hubeijusheng.com CHINA 22968 58

Related articles

View Lastest Price from Sennoside A manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Sennoside A pictures 2024-04-13 Sennoside A
81-27-6
US $0.00 / kg 1kg 99.8% 1000 kg BINBO BIOLOGICAL CO.,LTD
Sennoside A; Senna leaf extract pictures 2024-04-09 Sennoside A; Senna leaf extract
81-27-6
US $0.00 / KG 1KG 95%-99% HPLC 1000KG Changsha Staherb Natural Ingredients Co., Ltd.
Sennoside A pictures 2024-04-01 Sennoside A
81-27-6
US $0.00-0.00 / kg 20kg 99% 200000 Wuhan Haorong Biotechnology Co.,Ltd
  • Sennoside A pictures
  • Sennoside A
    81-27-6
  • US $0.00 / kg
  • 99.8%
  • BINBO BIOLOGICAL CO.,LTD
  • Sennoside A pictures
  • Sennoside A
    81-27-6
  • US $0.00-0.00 / kg
  • 99%
  • Wuhan Haorong Biotechnology Co.,Ltd

Sennoside A Spectrum

Sennoside A std. SENNOSIDEA60% SENNOSIDE A(P) SENNOSIDE A(SH) SENNOSIDA CALCIUM SENNOSIDE 5%, 10%, 20%, 60% [9,9'-Bianthracene]-2,2'-dicarboxylicacid,5,5'-bis(β-D-glucopyranosyloxy)-9,9',10,10'-tetrahydro-4,4'-dihydroxy-10,10'-dioxo-,(9R,9'R)- Sennoside A1 Einecs 201-339-9 Nsc 112929 SENNIDINE A(RG) Sennoside A ,98% Gentle Nature Glysennid Sennoside A (20 mg) SENNOSIDE A hplc SENNOSIDE A WITH HPLC 11,12-Epoxy-(5Z,8Z,14Z)-eicosatrienoic acid,11,12-EET Sennoside A (20 mg) ((9R,9'R)-5,5'-Bis(beta-d-glucopyranosyloxy)-4,4'-dihydroxy-10,10'-dioxo-9,9',10,10'-tetrahydro-9,9'-bianthracene-2,2'-dicarboxylic acid) Sennoside USP GLYSENNIDE SENNOSIDE SENNOSIDE A PURSENNID PURSENNIDE Tomato juice Pursenni 4,4',10,10'-Tetrahydroxy-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-[9,9'-bianthracene]-2,2'-dicarboxylic acid Sennoside A RS 4,4'-dihydroxy-10,10'-dioxo-5,5'-bis((3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid 81-27-6 Sennoside A Sennoside A ((9R,9''R)-5,5''-Bis(beta-d-glucopyranosyloxy)-4,4''-dihydroxy-10,10''-dioxo-9,9'',10,10''-te (1612018) (9R,9'R)-4,4'-Dihydroxy-10,10'-dioxo-5,5'-bis(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-9,9',10,10'-tetrahydro-[9,9'-bianthracene]-2,2'-dicarboxylic acid Sennoside A (6CI, 7CI, 8CI) 81-27-6 SA - SM Analytical Standards Alphabetic Analytical Chromatography Product Catalog The group of Sennosides Anthraquinones, Hydroquinones and Quinones chemical reagent pharmaceutical intermediate phytochemical reference standards from Chinese medicinal herbs (TCM). standardized herbal extract Inhibitors