ChemicalBook >> CAS DataBase List >>N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine

CAS No.
93285-75-7
Chemical Name:
N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine
Synonyms
Iaa-Biotin;IODOACETYL LC BIOTIN;Biotin-C6-iodoacetamide;N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE;N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE;N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine;N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE;N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine;N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin);(3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide
CBNumber:
CB5664328
Molecular Formula:
C18H31IN4O3S
Molecular Weight:
510.43
MDL Number:
MFCD00054987
MOL File:
93285-75-7.mol
Last updated:2023-04-23 13:52:06

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Properties

Boiling point 793.7±60.0 °C(Predicted)
Density 1.414±0.06 g/cm3 (20 ºC 760 Torr)
storage temp. Sealed in dry,2-8°C
solubility ≥51 mg/mL in DMSO with gentle warming; insoluble in EtOH; insoluble in H2O
form solid
pka 13.90±0.40(Predicted)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P271-P280-P304+P340
Hazard Codes  Xi
HS Code  2928009090

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC B396025 N-Biotinyl-N’-(iodoacetyl)-1,6-hexanediamine 93285-75-7 50mg $560 2021-12-16 Buy
BroadPharm BP-22638 Iodoacetyl-LC-Biotin 97% 93285-75-7 250mg $560 2021-12-16 Buy
American Custom Chemicals Corporation HCH0009003 N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE 95.00% 93285-75-7 100MG $715.75 2021-12-16 Buy
ApexBio Technology A8009 Iodoacetyl-LC-Biotin 93285-75-7 100mg $185 2021-12-16 Buy
BroadPharm BP-22638 Iodoacetyl-LC-Biotin 97% 93285-75-7 100mg $280 2021-12-16 Buy
Product number Packaging Price Buy
B396025 50mg $560 Buy
BP-22638 250mg $560 Buy
HCH0009003 100MG $715.75 Buy
A8009 100mg $185 Buy
BP-22638 100mg $280 Buy

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Chemical Properties,Uses,Production

Description

iodoacetyll-LC-Biotin is a sulfhydryl-reactive biotinylation reagent that forms stable, irreversible thioether bonds when reacting with with sulfhydryls (-SH) group at alkaline pH. The hexylenediamine spacer arm gives this reagent the membrane-impermeability which enables intracellular labeling of biomolecules.

Uses

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine can be a useful reagent for biotinylation of proteins and subsequent use in a protein microarray.

Uses

amine reactive biotinylation reagent

Biological Activity

iodoacetyl-lc-biotin (n-iodoacetyl-n-biotinylhexylenediamine), a sulfhydryl-reactive biotinylation agent, is a water-insoluble reagent that requires the dissolution of suitable solvents, including dimethyl sulfoxide (dmso) and dimethylformamide (dmf), prior to the addition into aqueous reactions. iodoacetyl-lc-biotin consists of a bicyclic biotin rings structure, a 1,6-diaminohexane spacer group attached to the valeric acid side chain of biotin and an iodoacetyl group at the end of the spacer providing sulfhydryl reactivity. the iodoacetyl group at the end of iodoacetyl-lc-biotin is able to react with sulfhydryl groups on proteins and other molecules forming a nonreversible bond. the long spacer arm of iodoacetyl-lc-biotin enables the modified molecule to better bind to the avidin or streptavidin probes.bioconjugate techniques , 2nd ed. by greg t.hermanson (pierce biotechnology, thermo fisher scientific, rockford, il). academic press (an imprint of elsevier): london, amsterdam, burlington, san diego . 2008. isbn 978-0-12-370501-3.

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 49)Suppliers
Supplier Tel Email Country ProdList Advantage
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hangzhou MolCore BioPharmatech Co.,Ltd.
+86-057181025280; +8617767106207 sales@molcore.com China 49739 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Xian confluore Biological Technology Co., Ltd.
+86-15680926068 +86-15680926068 1924344760@confluore.cn China 2893 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
J & K SCIENTIFIC LTD. 010-82848833 400-666-7788 jkinfo@jkchemical.com China 96815 76
3B Pharmachem (Wuhan) International Co.,Ltd. 821-50328103-801 18930552037 3bsc@sina.com China 15848 69
Chemsky (shanghai) International Co.,Ltd 021-50135380 shchemsky@sina.com China 15421 60
Spectrum Chemical Manufacturing Corp. 021-021-021-67601398-809-809-809 15221380277 marketing_china@spectrumchemical.com China 9664 60
Hangzhou Sage Chemical Co., Ltd. +86057186818502 13588463833 info@sagechem.com China 10269 58

View Lastest Price from N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Biotin-C6-iodoacetamide pictures 2024-04-02 Biotin-C6-iodoacetamide
93285-75-7
US $0.00 / mg 250mg >95.00% 250mg Xian confluore Biological Technology Co., Ltd.

N-Biotinyl-N'-(iodoacetyl)-1,6-hexanediaMine Spectrum

N-IODOACETYL-N'-BIOTINYLHEXYLENEDIAMINE N-IODOACETYL-N-BIOTINYLHEXYLENEDIAMINE N-BIOTINYL-N'-(IODOACETYL)-1,6-HEXANEDIAMINE IODOACETYL LC BIOTIN (3aS,4S,6aR)-Hexahydro-N-[6-[(iodoacetyl)amino]hexyl]-2-oxo-1H-thieno[3,4-d]imidazole-4-pentanamide N-Iodoacetyl-N'-biotinyl-1,6-hexanediamine (3aS,4S,6aR)-Hexahydro-N-[6-[(2-iodoacetyl)aMino]hexyl]-2-oxo-1H-thieno[3,4-d]iMidazole-4-pentanaMide 1H-Thieno[3,4-d]iMidazole-4-pentanaMide, hexahydro-N-[6-[(iodoacetyl)aMino]hexyl]-2-oxo-, (3aS,4S,6aR)- N-Iodoacetyl-N-biotinylhexylenediaMine(Iodoacetyl-LC-Biotin) N-Biotinyl-Na€-(iodoacetyl)-1,6-hexanediamine 1H-Thieno[3,4-d]imidazole-4-pentanamide, hexahydro-N-[6-[(2-iodoacetyl)amino]hexyl]-2-oxo-, (3aS,4S,6aR)- Iaa-Biotin N-(6-(2-Iodoacetamido)hexyl)-5-((3aS,4S,6aR)-2-oxohexahydro-1H-thieno[3,4-d]imidazol-4-yl)pentanamide Biotin-C6-iodoacetamide 93285-75-7 C18H31IN4O3S BiotinylationReagents MTS & Sulfhydryl Active Reagents Biotin Derivatives Cross Linking Reagents biotinyl