5-Cyanoindole
- CAS No.
- 15861-24-2
- Chemical Name:
- 5-Cyanoindole
- Synonyms
- 1H-INDOLE-5-CARBONITRILE;indoline-5-carbonitrile;5-Cyanoindolecas;Indolecarbonitrile;INDOLE-5-CARBONITRILE;5-Cyanoindole, 99% 1GR;5-CI;5-CYANOINDOLE;5-CYANOINDOLE 98%;5-Cyano-1H-indole
- CBNumber:
- CB5706833
- Molecular Formula:
- C9H6N2
- Molecular Weight:
- 142.16
- MDL Number:
- MFCD00005669
- MOL File:
- 15861-24-2.mol
- MSDS File:
- SDS
| Melting point | 106-108 °C(lit.) |
|---|---|
| Boiling point | 249.72°C (rough estimate) |
| Density | 1.1777 (rough estimate) |
| refractive index | 1.6211 (estimate) |
| storage temp. | Keep in dark place,Inert atmosphere,Room temperature |
| solubility | Chloroform, Hexane, Methanol |
| form | Crystalline Powder |
| pka | 15.62±0.30(Predicted) |
| color | White to slightly yellow |
| Water Solubility | Soluble in chloroform, hexane and methanol. Insoluble in water. |
| Sensitive | Air & Light Sensitive |
| BRN | 116738 |
| InChIKey | YHYLDEVWYOFIJK-UHFFFAOYSA-N |
| CAS DataBase Reference | 15861-24-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302+H312+H332-H315-H319-H302-H335 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P280-P301+P312+P330-P302+P352+P312+P362+P364-P304+P340+P312-P305+P351+P338+P337+P313-P501-P280a-P304+P340-P305+P351+P338-P405-P501a | |||||||||
| Hazard Codes | Xi,Xn | |||||||||
| Risk Statements | 36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-36-22 | |||||||||
| RIDADR | 3276 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | NL5993120 | |||||||||
| F | 8-10 | |||||||||
| Hazard Note | Irritant | |||||||||
| HazardClass | 6.1 | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29339990 | |||||||||
| NFPA 704 |
|
5-Cyanoindole price More Price(40)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | C92006 | Indole-5-carbonitrile 99% | 15861-24-2 | 5g | $71.6 | 2024-03-01 | Buy |
| Sigma-Aldrich | C92006 | Indole-5-carbonitrile 99% | 15861-24-2 | 10g | $131 | 2023-06-20 | Buy |
| TCI Chemical | C1491 | 5-Cyanoindole >98.0%(GC) | 15861-24-2 | 1g | $27 | 2024-03-01 | Buy |
| TCI Chemical | C1491 | 5-Cyanoindole >98.0%(GC) | 15861-24-2 | 5g | $77 | 2024-03-01 | Buy |
| Alfa Aesar | B21810 | Indole-5-carbonitrile, 98+% | 15861-24-2 | 1g | $47.65 | 2024-03-01 | Buy |
5-Cyanoindole Chemical Properties,Uses,Production
Chemical Properties
Off-White Crystalline Powder
Uses
Reactant used for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction, preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM, chemo selective and regioselective preparation of benzoyl indoles, 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant and vinylindoles by hydroarylation of alkynes using indium bromide catalyst.
Uses
• ;Reactant for parallel synthesis of dihydroisoquinolines via silver and L-proline co-catalyzed three-component coupling reaction1• ;Reactant for chemoselective and regioselective preparation of benzoyl indoles2• ;Reactant for preparation of novel PPARα/γ dual agonists for potential treatment of metabolic syndrome and IDDM3• ;Reactant for preparation of 4,5-dihydrocyclopenta[c]quinolines by palladium-catalyzed ring-expansion reaction alkynes, using O2 as the oxidant4• ;Reactant for preparation of vinylindoles by hydroarylation of alkynes using indium bromi
Uses
Inhibitor of enzyme.
Purification Methods
Dissolve the nitrile in 95% EtOH, boil it in the presence of charcoal, filter, evaporate to a small volume and add enough H2O to cause crystallisation and cool. Recrystallise it directly from aqueous EtOH and dry it in a vacuum. UV has at max 276 nm (log 3.6) in MeOH. [Lindwall & Mantell J Org Chem 18 345 1953, 20 1458 1955, Thesing at al. Chem Ber 95 2205 1962, NMR: Lallemend & Bernath Bull Soc Chim Fr 4091 1970, Beilstein 22/3 V 45.]
5-Cyanoindole Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Shanxi Naipu Import and Export Co.,Ltd | +86-13734021967 +8613734021967 | kaia@neputrading.com | China | 1011 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Zhejiang ZETian Fine Chemicals Co. LTD | 18957127338 | stella@zetchem.com | China | 2141 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Jinan Finer Chemical Co., Ltd | +86-531-88989536 +86-15508631887 | sales@finerchem.com | China | 2967 | 58 |
| Accela ChemBio Inc. | (+1)-858-699-3322 | info@accelachem.com | United States | 19965 | 58 |
| Xiamen AmoyChem Co., Ltd | +86-592-6051114 +8618959220845 | sales@amoychem.com | China | 6387 | 58 |
| Shandong chuangyingchemical Co., Ltd. | 18853181302 | sale@chuangyingchem.com | CHINA | 5909 | 58 |
View Lastest Price from 5-Cyanoindole manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2022-11-15 | 5-Cyanoindole
15861-24-2
|
US $200.00 / g | 10g | 99% | 1000t/month | Hebei Best Biological Technology Co., Ltd | |
 |
2022-09-20 | 5-Cyanoindole
15861-24-2
|
US $0.00-0.00 / kg | 1kg | 98% | 1Ton | Henan Aochuang Chemical Co.,Ltd. | |
 |
2022-02-25 | 5-Cyanoindole
15861-24-2
|
US $10.00 / KG | 1KG | 99% | 500tons/month | Shanxi Naipu Import and Export Co.,Ltd |
-
- 5-Cyanoindole
15861-24-2
- US $200.00 / g
- 99%
- Hebei Best Biological Technology Co., Ltd
-
- 5-Cyanoindole
15861-24-2
- US $0.00-0.00 / kg
- 98%
- Henan Aochuang Chemical Co.,Ltd.
-
- 5-Cyanoindole
15861-24-2
- US $10.00 / KG
- 99%
- Shanxi Naipu Import and Export Co.,Ltd