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2-Methylpropanedioic acid

2-Methylpropanedioic acid structure

CAS No.: 516-05-2

Chemical Name:: 2-Methylpropanedioic acid

Synonyms: METHYLMALONIC ACID;2-Methylmalonic acid;AI315327;NSC 25201;onic acid;AI3 15327;AI3-15327;Methylmalonic;isosuccinicacid;Isosuccinic acid

CBNumber:: CB5713714

Molecular Formula:: C4H6O4

Molecular Weight:: 118.09

MDL Number:: MFCD00002656

MOL File:: 516-05-2.mol

MSDS File:: SDS

Last updated:2023-08-24 17:20:48

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2-Methylpropanedioic acid Properties

Melting point	128-130 °C (lit.)
Boiling point	272.71°C (rough estimate)
Density	1.45
refractive index	1.4304 (estimate)
Flash point	2℃
storage temp.	Sealed in dry,Room Temperature
solubility	DMSO (Slightly), Methanol (Slightly)
form	Crystalline Powder
pka	3.07, 5.76(at 25℃)
color	White
Specific Gravity	1.455
PH	3.23(1 mM solution);2.6(10 mM solution);2.05(100 mM solution)
Water Solubility	soluble
BRN	1756084
CAS DataBase Reference	516-05-2(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	8LL8S712J7
NIST Chemistry Reference	Methylmalonic acid(516-05-2)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H315-H319-H335

Precautionary statements

P302+P352-P305+P351+P338

Hazard Codes

Xi,Xn,F

Risk Statements

36/37/38-36-20/21/22-11

Safety Statements

26-36/37-16

RIDADR

UN 1648 3 / PGII

WGK Germany

RTECS

OO1400000

HS Code

29171900

NFPA 704

	0
1		0

2-Methylpropanedioic acid price More Price(29)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	M54058	Methylmalonic acid 99%	516-05-2	5g	$65.8	2024-03-01	Buy
Sigma-Aldrich	M-080	Methylmalonic acid solution 1.0?mg/mL in acetonitrile, ampule of 1?mL, certified reference material, Cerilliant?	516-05-2	1mL	$113	2024-03-01	Buy
TCI Chemical	M0568	Methylmalonic Acid >98.0%(T)	516-05-2	25g	$74	2024-03-01	Buy
Cayman Chemical	14885	Methylmalonate ≥95%	516-05-2	1g	$20	2024-03-01	Buy
Cayman Chemical	14885	Methylmalonate ≥95%	516-05-2	5g	$48	2024-03-01	Buy

Product number	Packaging	Price	Buy
M54058	5g	$65.8	Buy
M-080	1mL	$113	Buy
M0568	25g	$74	Buy
14885	1g	$20	Buy
14885	5g	$48	Buy

2-Methylpropanedioic acid Chemical Properties,Uses,Production

Chemical Properties

white crystalline powder

Uses

Methylmalonic acid can be used as a substrate in:

Esterification reactions by various catalysts.
Synthesis of pyrimidinium betaines with formamidine.
Synthesis of malonic acid half thioester (MAHT).

Uses

2-Methylpropanedioic acid binds with coenzyme A to form methylmalonyl-CoA, also a metabolic intermediate transformed to succinic acid (SA) by a vitamin B12-dependent catalytic step, and is broadly used as a clinical biomarker of functional vitamin B12 status.

Definition

ChEBI: A dicarboxylic acid that is malonic acid in which one of the methylene hydrogens is substituted by a methyl group.

Biological Functions

Methylmalonic acid is capable of diffusing out of cells in which it is being produced, so it may be detected in excess in the blood, CSF, and urine of patients with these various forms of the disease.

General Description

Methylmalonic acid is an indicator of vitamin B₁₂ deficiency and methylmalonic acidemia. This Certified Spiking Solution^? is suitable for use in preparation of calibrators or controls in clinical and diagnostic testing using GC/MS or LC/MS.

storage

Store at RT

Purification Methods

The acid crystallises as the hydrate from water. [Beilstein 2 IV 1932.]

2-Methylpropanedioic acid Preparation Products And Raw materials

Raw materials

1,3-Di-tert-butyl2-methylpropanedioate 3-ethoxy-2-Methyl-3-oxopropanoic acid Propanoic acid, 2-cyano- Dimethyl methylmalonate DIETHYL MERCURY

4-METHYL-PYRIDINE-2-CARBOXYLIC ACID Diethyl methylmalonate 2-Chloropropionic acid

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Preparation Products

cyclamen aldehyde 5-hydroxy-3-Methyl-2(5H)-furanone 2-Propenoic acid, 3-(2,6-dichlorophenyl)-2-methyl- Benzenepropanoic acid, β-amino-α-methyl-, (αR,βS)-rel- 2H-Pyrano[3,2-c]pyridine-2,5(6H)-dione, 4-hydroxy-3,6,7-trimethyl- (9CI)

2-Methylpropanedioic acid Suppliers

Global( 291)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12456	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Accela ChemBio Inc.	(+1)-858-699-3322	info@accelachem.com	United States	19965	58
Hebei Guanlang Biotechnology Co., Ltd.	+86-19930503282	alice@crovellbio.com	China	8823	58
Chongqing Chemdad Co., Ltd	+86-023-61398051 +8613650506873	sales@chemdad.com	China	39916	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
CONIER CHEM AND PHARMA LIMITED	+8618523575427	sales@conier.com	China	49390	58
Hefei TNJ Chemical Industry Co.,Ltd.	0551-65418671	sales@tnjchem.com	China	34572	58
ANHUI WITOP BIOTECH CO., LTD	+8615255079626	eric@witopchemical.com	China	23556	58

Supplier	Advantage
Hebei Mojin Biotechnology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
career henan chemical co	58
Accela ChemBio Inc.	58
Hebei Guanlang Biotechnology Co., Ltd.	58
Chongqing Chemdad Co., Ltd	58
Alchem Pharmtech,Inc.	58
CONIER CHEM AND PHARMA LIMITED	58
Hefei TNJ Chemical Industry Co.,Ltd.	58
ANHUI WITOP BIOTECH CO., LTD	58

View Lastest Price from 2-Methylpropanedioic acid manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2023-08-24	2-Methylpropanedioic acid 516-05-2	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2021-04-27	2-Methylpropanedioic acid 516-05-2	US $1.00 / PCS	1KG	99%	10 mt	Hebei Guanlang Biotechnology Co., Ltd.
2019-07-06	2-Methylpropanedioic acid 516-05-2	US $1.00 / KG	1KG	99%	Customized	Career Henan Chemical Co

2-Methylpropanedioic acid
516-05-2
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

2-Methylpropanedioic acid
516-05-2
US $1.00 / PCS
99%
Hebei Guanlang Biotechnology Co., Ltd.

2-Methylpropanedioic acid
516-05-2
US $1.00 / KG
99%
Career Henan Chemical Co

2-Methylpropanedioic acid Spectrum

2-Methylpropanedioic acid(516-05-2)MS 2-Methylpropanedioic acid(516-05-2)¹HNMR 2-Methylpropanedioic acid(516-05-2)¹³CNMR 2-Methylpropanedioic acid(516-05-2)IR1 2-Methylpropanedioic acid(516-05-2)IR2 2-Methylpropanedioic acid(516-05-2)Raman

516-05-2(2-Methylpropanedioic acid)Related Search:

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Flurbiprofen Impurity 15 2,4-Difluorobiphenyl diethyl (3-fluoro-4-nitrophenyl)methylmalonate 4'-hydroxyflurbiprofen 2-Fluorobiphenyl-4-carboxylic Acid

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