azafenidin
- CAS No.
- 68049-83-2
- Chemical Name:
- azafenidin
- Synonyms
- C10895;R 6447;Evolus;Milestone;IN-R 6447;DPX-R 6447;azafenidin;2-(2,4-dichloro-5-prop-2-ynyloxyphenyl)-5,6,7,8-tetrahydro-1,2,4-triazole(4,3-a)pyridin-3(2H)-one;2-(2,4-dichloro-5-prop-2-ynyloxypnenyl)-5,6,7,8-tetrahy-dro-1,2,4-trizolo [4,3-α] pyridin-3-(2H)-one;1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one, 2-[2,4-dichloro-5-(2-propyn-1-yloxy)phenyl]-5,6,7,8-tetrahydro-
- CBNumber:
- CB5945861
- Molecular Formula:
- C15H13Cl2N3O2
- Molecular Weight:
- 338.19
- MDL Number:
- MFCD30720402
- MOL File:
- 68049-83-2.mol
| Melting point | 168-168.5° |
|---|---|
| Boiling point | 468.9±55.0 °C(Predicted) |
| Density | 1.43±0.1 g/cm3(Predicted) |
| solubility | DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 2.45±0.20(Predicted) |
| color | Brown to Dark Brown |
| EWG's Food Scores | 2 |
| FDA UNII | XQK9668H5M |
| EPA Substance Registry System | Azafeniden (68049-83-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |   GHS08,GHS09 |
|---|---|
| Signal word | Danger |
| Hazard statements | H360Df-H373-H410 |
| Precautionary statements | P260-P314-P501-P273-P391-P501 |
| Hazard Codes | T,N |
| Risk Statements | 61-48/22-62-50/53 |
| Safety Statements | 53-45-60-61 |
| Toxicity | LD50 in rats, mice, bobwhite quail, mallard duck (mg/kg): >5000, >5000, >2500, >2500 orally; in rabbits (mg/kg): >2000 dermally.; LC50 in rats, rainbow trout, blue gill sunfish (mg/l): >5.3, 33, 48 (Amuti) |
azafenidin price
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| TRC | A797400 | Azafenidin | 68049-83-2 | 0.5mg | $195 | 2021-12-16 | Buy |
| American Custom Chemicals Corporation | AGR0000375 | AZAFENIDIN 95.00% | 68049-83-2 | 5MG | $496.14 | 2021-12-16 | Buy |
| Medical Isotopes, Inc. | 38782 | Azafenidin | 68049-83-2 | 5mg | $990 | 2021-12-16 | Buy |
azafenidin Chemical Properties,Uses,Production
Uses
Herbicide.
Uses
Azafenidin is a weed controlling herbicide used in various crops.
Definition
ChEBI: Azafenidin is a triazolopyridine that is 5,6,7,8-tetrahydro[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one which is substituted at position 2 by a 2,4-dichloro-5-(prop-2-yn-1-yloxy)phenyl group. A protoporphyrinogen oxidase inhibitor, it is used as a herbicide to control weeds in fruit crops such as pineapple, citrus, melons, and grapes. Not approved for use within the European Union. It has a role as an EC 1.3.3.4 (protoporphyrinogen oxidase) inhibitor. It is a triazolopyridine, a terminal acetylenic compound and a dichlorobenzene.
Metabolic pathway
A common degradation reaction of azafenidin in light, plants and soil is O-dealkylation, and interesting minor reactions in soil are the subsequent methylation of the O-dealkylated degradation product and the reduction of the propynyl group under anaerobic conditions. In soil and light, azafenidin is also readily split to form the triazolinone heterocycle. Azafenidin is readily metabolized in rats and lactating goats through O-dealkylation, hydroxylation of the triazolinone ring in several positions, and glucuronide and sulfate conjugation.
azafenidin Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Zibo Hangyu Biotechnology Development Co., Ltd | +86-0533-2185556 +8617865335152 | Mandy@hangyubiotech.com | China | 11013 | 58 |
| J & K SCIENTIFIC LTD. | 010-82848833 400-666-7788 | jkinfo@jkchemical.com | China | 96815 | 76 |
| Shanghai TaoSu Biochemical Technology Co., Ltd. | 021-33632979 | info@tsbiochem.com | China | 8073 | 58 |
| Shenzhen SUNGENING Bio-Medical Co., Ltd. | 0755-28967200 13631290199 | wxf@sungening.com | China | 9506 | 60 |
| Shenzhen Polymeri Biochemical Technology Co., Ltd. | +86-400-002-6226 13028896684 | sales@rrkchem.com | China | 55717 | 58 |
| Huansheng Meisen Pharmaceutical Technology (Shandong) Co., Ltd | 0531-88762217 18301471076 | sales@acespharma.com | China | 3858 | 58 |
| Shandong Mopai Biotechnology Co., Ltd | 13053322091 13053322091 | admin@mopaikeji.com | China | 10968 | 58 |
| Nantong Zhonghe Chemical New Materials Co., Ltd | 13003551299 13003551299 | 2369399482@qq.com | China | 7568 | 58 |