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AMIPROFOS METHYL

CAS No.
36001-88-4
Chemical Name:
AMIPROFOS METHYL
Synonyms
ntn80;ntn6867;bayntn80;NTN-2925;Tokunol-M;bayntn6867;amiprophosmethyl;AMIPROFOS METHYL;Amiprofosmethylbiochemika;O-METHYL O-(2-NITRO-P-TOLYL) N-ISOPROPYL-PHOSPHORAMIDOTHIONATE
CBNumber:
CB6124212
Molecular Formula:
C11H17N2O4PS
Molecular Weight:
304.3
MDL Number:
MFCD00467096
MOL File:
36001-88-4.mol
MSDS File:
SDS
Last updated:2023-06-08 09:02:03

AMIPROFOS METHYL Properties

Melting point ~65 °C
Boiling point 146.6°C
Density 1.275±0.06 g/cm3(Predicted)
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka -0.73±0.70(Predicted)
color White to Off-White
BRN 2000833
FDA UNII D130E8V1ON
EPA Substance Registry System Amiprofos-methyl (36001-88-4)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn
Risk Statements  22
Safety Statements  36
WGK Germany  3
RTECS  TB5100000
Toxicity LD50 orl-rat: 309 mg/kg 85AREA 2,212,77
NFPA 704
0
2 0

AMIPROFOS METHYL price More Price(11)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 03992 Amiprofos methyl PESTANAL , analytical standard 36001-88-4 50mg $237 2023-06-20 Buy
Cayman Chemical 23379 Amiprofos methyl ≥98% 36001-88-4 5mg $32 2023-06-20 Buy
Cayman Chemical 23379 Amiprofos methyl ≥98% 36001-88-4 10mg $60 2023-06-20 Buy
Cayman Chemical 23379 Amiprofos methyl ≥98% 36001-88-4 50mg $101 2024-03-01 Buy
Cayman Chemical 23379 Amiprofos methyl ≥98% 36001-88-4 100mg $185 2024-03-01 Buy
Product number Packaging Price Buy
03992 50mg $237 Buy
23379 5mg $32 Buy
23379 10mg $60 Buy
23379 50mg $101 Buy
23379 100mg $185 Buy

AMIPROFOS METHYL Chemical Properties,Uses,Production

Description

Amiprofos-methyl (APM) is a phosphoric amide herbicide. It reversibly decreases H. vulgare root and shoot length and inhibits in vitro polymerization of Rosa tubulin induced by paclitaxel in a dose-dependent manner. APM completely inhibits tubulin polymerization in Hemanthus endosperm cells at a concentration of 0.1 μM. The antitubulin effects of APM are specific to plants as it has no effect on bovine brain tubulin polymerization at concentrations up to 100 μM. APM inhibits calcium accumulation in corn mitochondria (ID50 = 140 nM) and induces a 3-fold increase in the rate of calcium efflux from rat liver mitochondria at a concentration of 100 nM. APM inhibits the growth of P. falciparum (IC50 = 3.5 μM) and completely inhibits microtubule polymerization in P. falciparum trophozoites at a concentration of 20 μM.

Uses

Amiprofos-methyl is useful in herbicide compositions.

Biochem/physiol Actions

Herbicide that prevents microtubule polymerization in plant cells, but not animal cells. Crop plants resistant to amiprofos-methyl and several other herbicides have been developed by insertion of a xenobiotic-detoxifying human gene CYP2B6.

Safety Profile

A poison by ingestion. Lowtoxicity by skin contact. When heated to decomposition itemits toxic vapors of NOx, SOx, and POx.

AMIPROFOS METHYL Preparation Products And Raw materials

Global( 56)Suppliers
Supplier Tel Email Country ProdList Advantage
Hubei Jusheng Technology Co.,Ltd.
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Hefei TNJ Chemical Industry Co.,Ltd.
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LEAP CHEM CO., LTD.
+86-852-30606658 market18@leapchem.com China 24738 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 57511 58
Beijing VSciChem Technology Co., Ltd. 13811761079 vscichem@163.com China 245 64
Hangzhou J&H Chemical Co., Ltd. +86-571-87396432 0571-87396433 sales@jhechem.com China 10015 53
Sigma-Aldrich 021-61415566 800-8193336 orderCN@merckgroup.com China 51471 80
Alta Scientific Co., Ltd. 022-6537-8550 15522853686 sales@altasci.com.cn China 4515 55
Shanghai YuanYe Biotechnology Co., Ltd. 021-61312847; 18021002903 3008007409@qq.com China 27322 60
Tianjin heowns Biochemical Technology Co., Ltd. 400-6387771-6037 18920794737 sales@heowns.com China 20495 60
amiprophosmethyl bayntn6867 bayntn80 n-isopropyl-phosphoramidothioicacio-methylo-(2-nitro-p-tolyl)ester ntn6867 O-METHYL O-(2-NITRO-P-TOLYL) N-ISOPROPYL-PHOSPHORAMIDOTHIONATE AMIPROFOS METHYL ntn80 o-methylo-(4-methyl-2-nitrophenyl)(1-methylethyl)phosphoramidothioate O-methyl O-(4-methyl-2-nitrophenyl) isopropylthiophosphoramidate Amiprofosmethylbiochemika O-methyl-O-(2-nitro-4-methylpehnyl)-N-isopropylphosphoramidothioate Tokunol-M N-Isopropylphosphoramidothioic acid O-methyl O-(4-methyl-2-nitrophenyl) NTN-2925 Amiprofos methyl,O-Methyl O-(2-nitro-p-tolyl) N-isopropylphosphoramidothionate Phosphoramidothioic acid, N-(1-methylethyl)-, O-methyl O-(4-methyl-2-nitrophenyl) ester O-methyl O-(4-methyl-2-nitrophenyl) isopropylthiophosphorami... 36001-88-4 C11H17N2O4PS Biochemicals and Reagents BioChemical Enzymes, Inhibitors, and Substrates Enzyme Inhibitors by Type Enzyme Inhibitors Substrate Analogs