Ethyl trichloroacetate
- CAS No.
- 515-84-4
- Chemical Name:
- Ethyl trichloroacetate
- Synonyms
- Acetic acid, trichloro-, ethyl ester;Trichloroaceta;RARECHEM AL BI 1451;Ethyltrichloracetat;ethyltrichloracetate;Biapenem Impurity 45;Ethyl trichloroacetat;Tadalafil Impurity 69;Trichloroethyl acetate;ETHYL TRICHLOROACETATE
- CBNumber:
- CB6143392
- Molecular Formula:
- C4H5Cl3O2
- Molecular Weight:
- 191.44
- MDL Number:
- MFCD00000795
- MOL File:
- 515-84-4.mol
- MSDS File:
- SDS
| Melting point | 237 °C |
|---|---|
| Boiling point | 168 °C (lit.) |
| Density | 1.378 g/mL at 25 °C (lit.) |
| vapor pressure | 2.34hPa at 25℃ |
| refractive index |
n |
| Flash point | 149 °F |
| storage temp. | Store below +30°C. |
| solubility | alcohol: miscible(lit.) |
| form | clear liquid |
| color | Colorless to Almost colorless |
| Water Solubility | immiscible |
| Merck | 14,9627 |
| BRN | 1761567 |
| Dielectric constant | 7.8（20℃） |
| LogP | 2.22 at 25℃ |
| CAS DataBase Reference | 515-84-4(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | BR8FKN5Z55 |
| NIST Chemistry Reference | Acetic acid, trichloro-, ethyl ester(515-84-4) |
| EPA Substance Registry System | Acetic acid, trichloro-, ethyl ester (515-84-4) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P332+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38 | |||||||||
| Safety Statements | 26-37/39-24/25 | |||||||||
| RIDADR | 2810 | |||||||||
| WGK Germany | 1 | |||||||||
| HS Code | 29154000 | |||||||||
| NFPA 704 |
|
Ethyl trichloroacetate price More Price(12)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 163155 | Ethyl trichloroacetate 97% | 515-84-4 | 100g | $107 | 2024-03-01 | Buy |
| TCI Chemical | T1504 | Ethyl Trichloroacetate >97.0%(GC) | 515-84-4 | 25g | $45 | 2024-03-01 | Buy |
| TCI Chemical | T1504 | Ethyl Trichloroacetate >97.0%(GC) | 515-84-4 | 500g | $248 | 2024-03-01 | Buy |
| Frontier Specialty Chemicals | JK155499 | Ethyl trichloroacetate | 515-84-4 | 500g | $143 | 2021-12-16 | Buy |
| AK Scientific | V2098 | Ethyl trichloroacetate | 515-84-4 | 25g | $49 | 2021-12-16 | Buy |
Ethyl trichloroacetate Chemical Properties,Uses,Production
Chemical Properties
Colorless liquid with a menthol-like odor. It is miscible with ethanol, ether and benzene, but insoluble in water.
Uses
Ethyl trichloroacetate was used in the synthesis of dichlorocarbon precursor, phenyl(trichloromethyl)methyl.
Application
Ethyl trichloroacetate can be used as solvent, organic synthesis, perfume and pharmaceutical intermediates.
Preparation
Ethyl trichloroacetate is synthesized from trichloroacetic acid and ethyl alcohol by the esterification reaction.
synthesis steps: Trichloroacetic acid(TCA), anhydrous ethyl alcohol and sulfuric acid are heated together and refluxed for 6 h. After cooling, the ester layer is separated by pouring into water, neutralized with 5-10% sodium carbonate solution, washed with water and dried overnight with anhydrous calcium chloride. After filtration, distillation was carried out to obtain the finished product. Yield 75%.
Synthesis Reference(s)
The Journal of Organic Chemistry, 46, p. 3519, 1981 DOI: 10.1021/jo00330a028
General Description
Ethyl trichloroacetate undergoes atom-transfer radical addition reaction with styrene catalyzed by the Ru-pentamethylcyclopentadienyl complexes.
Purification Methods
Shake the ester with saturated aqueous Na2CO3 (three times), aqueous 50% CaCl2 (three times), saturated aqueous NaCl (twice), then distil over CaCl2 and redistil it under reduced pressure. [Beilstein 2 IV 514.]
Ethyl trichloroacetate Preparation Products And Raw materials
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| Hefei TNJ Chemical Industry Co.,Ltd. | +86-0551-65418679 +86-18949832763 | info@tnjchem.com | China | 2989 | 55 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Guangzhou Yuheng Pharmaceutical Technology Co., Ltd | +8613580539051 | joe@yuhengpharm.com | CHINA | 21149 | 58 |
| Longyan Tianhua Biological Technology Co., Ltd | 0086 18039857276 18039857276 | CHINA | 2783 | 58 | |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| ANHUI WITOP BIOTECH CO., LTD | +8615255079626 | eric@witopchemical.com | China | 23556 | 58 |
| Aston Chemical | 13000000000 | sales@astonchem.com | United States | 1634 | 58 |
View Lastest Price from Ethyl trichloroacetate manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-09-06 | Ethyl trichloroacetate
515-84-4
|
US $0.00-0.00 / KG | 1KG | 99% | 500000kg | Hebei Guanlang Biotechnology Co., Ltd. | |
 |
2023-05-10 | Ethyl Trichloroacetate
515-84-4
|
US $5.00-2.00 / KG | 1KG | 99% | 10000kg | Hebei Guanlang Biotechnology Co,.LTD | |
 |
2019-07-06 | Ethyl trichloroacetate
515-84-4
|
US $1.00 / kg | 1kg | 98%min | as request | Career Henan Chemical Co |
-
- Ethyl trichloroacetate
515-84-4
- US $0.00-0.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co., Ltd.
-
- Ethyl Trichloroacetate
515-84-4
- US $5.00-2.00 / KG
- 99%
- Hebei Guanlang Biotechnology Co,.LTD
-
- Ethyl trichloroacetate
515-84-4
- US $1.00 / kg
- 98%min
- Career Henan Chemical Co