ChemicalBook >> CAS DataBase List >>(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
- CAS No.
- 39637-99-5
- Chemical Name:
- (S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
- Synonyms
- MOSHER'S ACID CHLORIDE;(-)-Mosher's Acid Chloride;(+)-MTPA-CL;(R)-(−(S)-(+)-MTPA-CL;(R)-MTPA chloride;(R)-(-)-Acid chloride;(+)-MOSHER'S CHLORIDE;(+)-MOSHER'S ACID CHLORIDE;(R)-(-)-Mosher'sacidchloride
- CBNumber:
- CB6170769
- Molecular Formula:
- C10H8ClF3O2
- Molecular Weight:
- 252.62
- MDL Number:
- MFCD00044400
- MOL File:
- 39637-99-5.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| alpha | D25 -10.0± 0.1° (neat, l = 1) |
|---|---|
| Boiling point | 213-214 °C(lit.) |
| Density | 1.35 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | 194 °F |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| form | Liquid |
| color | Clear colorless to light yellow |
| Specific Gravity | 1.353 |
| optical activity | [α]20/D 137±2°, c = 6.4% in carbon tetrachloride |
| Water Solubility | Sparingly miscible with water. |
| Sensitive | Moisture Sensitive |
| Merck | 14,6280 |
| BRN | 3591565 |
| CAS DataBase Reference | 39637-99-5(CAS DataBase Reference) |
| FDA UNII | 81UT10UHV3 |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS05 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H314 | |||||||||
| Precautionary statements | P280-P301+P330+P331-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363 | |||||||||
| Hazard Codes | C | |||||||||
| Risk Statements | 34 | |||||||||
| Safety Statements | 26-27-36/37/39-45 | |||||||||
| RIDADR | UN 3265 8/PG 2 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 10-21 | |||||||||
| Hazard Note | Corrosive/Freeze | |||||||||
| HazardClass | 8 | |||||||||
| PackingGroup | II | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE price More Price(22)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 65363 | (R)-(?)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride for chiral derivatization, ≥99.0% | 39637-99-5 | 100mg | $147 | 2024-03-01 | Buy |
| Sigma-Aldrich | 65363 | (R)-(?)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride for chiral derivatization, ≥99.0% | 39637-99-5 | 500mg | $578 | 2024-03-01 | Buy |
| TCI Chemical | M1104 | (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines] >98.0%(GC) | 39637-99-5 | 100mg | $55 | 2024-03-01 | Buy |
| TCI Chemical | M1104 | (R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines] >98.0%(GC) | 39637-99-5 | 1g | $322 | 2024-03-01 | Buy |
| Alfa Aesar | L14325 | (R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+% | 39637-99-5 | 50mg | $54.9 | 2024-03-01 | Buy |
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE Chemical Properties,Uses,Production
Chemical Properties
clear colorless to light yellow liquid
Uses
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride is used as a chiral acylating reagent, which is used in the resolution of amino acid enantiomers like 2,5-dimethoxy-4-methylamphetamine. It is also suitable for the determination of the optical composition of compounds extracted from biological fluids.
Purification Methods
The most likely impurity is the free acid due to hydrolysis and should be checked by IR. If free from acid, then distil, taking care to keep moisture out of the apparatus. Otherwise add SOCl2 and reflux for 5hours and distil it. Note that shorter reflux times result in a higher boiling fraction (b 130-155o/1mm) which has been identified as the anhydride. [Dale et al. J Org Chem 34 2543 1969, for enantiomeric purity see Dale & Mosher J Am Chem Soc 97 512 1973.]
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE Preparation Products And Raw materials
Raw materials
Preparation Products
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE Suppliers
Global( 111)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| Alfa Chemistry | +1-5166625404 | Info@alfa-chemistry.com | United States | 21317 | 58 |
| VladaChem GmbH | +49-7246-3082843 | info@vladachem.de | Germany | 1860 | 58 |
| LEAPCHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 43348 | 58 |
| Jilin Chinese Academy of Sciences-yanshen Technology | +undefined18143011203 | info@chemextension.com | China | 42057 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 57511 | 58 |
| Aladdin Scientific | +1-833-552-7181 | sales@aladdinsci.com | United States | 52927 | 58 |
| Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 131981 | 58 |
View Lastest Price from (S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2020-01-10 | (S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
39637-99-5
|
US $1.00 / KG | 1KG | 99% | 200kg | Career Henan Chemical Co |
-
- (S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
39637-99-5
- US $1.00 / KG
- 99%
- Career Henan Chemical Co
39637-99-5((S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE)Related Search:
3,3,3-TRIFLUOROPROPIONYL CHLORIDE
Phenylacetyl chloride
(+/-)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE,ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
3-CHLORO-1,1,1-TRIFLUOROPROPANE
(R)-1-Chloro-2-propanol
1-CHLORO-2-METHYL-2-PROPANOL
Methoxyacetyl chloride
1-PHENYL-2,2,2-TRIFLUOROETHANOL
1-Pentanol
1of4
(R)-(fi)-alpha-methoxy-alpha-trifluoromethylphenylacetylchloride
(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride, 98+%
(R)-(-)-MTPA-Cl, Moshers acid chloride
(S)-2-Methoxy-2-phenyl-3,3,3-trifluoropropionic acid chloride
(S)-2-Methoxy-3,3,3-trifluoro-2-phenylpropionic acid chloride
(S)-2-Phenyl-2-methoxy-3,3,3-trifluoropropionic acid chloride
[S,(+)]-α-Methoxy-α-(trifluoromethyl)benzeneacetic acid chloride
(R)-(-)-^a-Methoxy-^a-(trifluoromethyl)phenylacetyl chloride, 98+%
(R)-(-)-α-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride
(R)-(-)-α-Methoxy-α-(trifluoromethyl)benzeneacetylchloride
(-)-MTPA-Cl
(R)-()-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride,(R)-()-MTPA-Cl, Mosher’s acid chloride
(1R)-(-)-1-Methoxy-1-(trifluoromethyl)phenylacetyl chloride 99% (99%ee)
(R)-(-)-alpha-Methoxy-alpha-trifluoromethylphenylacetyl chloride, 97+%
(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99% (99%ee)
(R)-(-)-MTPACl, (R)-(-)-Mosher's acid chloride, (2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropionyl chloride
(-)-alpha-Methoxy-alpha-(trifluoroMethyl)phenylacetyl Chloride
[for DeterMination of the optical purity of Alcohols and AMines]
(R)-2-Methoxy-2-(trifluoromethyl)phenylacetyl chloride
(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoylchloride99%
(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl chloride,99%
(2R)-(-)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoyl chloride 99%
(R)-(-)-alphaMethoxy-alpha(three fluoroMethyl)phenyl acetyl chloride
(R)-MTPA chloride
(R)-(-)-Acid chloride
(R)-(-)-A-METHOXY-A-(TRIFLUOROMETHYL)-PH ENYLACETYL CHLORIDE, 98%(98% EE/GLC)
(R)-(-)-Mosher'sacidchloride
(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetylchloride(ee)
(-)--Methoxy--(trifluoromethyl)phenylacetylchloride
(r)-(-)-à-methoxy-à-(trifluoromethyl)phenylacetyl chloride
(R)-(-)-1-Methoxy-1-(trifluoromethyl)phenylacetyl chloride 99% (99%ee)
(r)-(-)-alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride (R)-(fi)-alpha-methoxy-alpha-trifluoromethylphenylacetyl chloride (r)-(-)-a-methoxy-a-(trifluoromethyl) phenylacetyl chloride
(R)-(-)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE 99%
(R)-(-)-1-Methoxy-1-(trifluoromethyl)phenylacetyl chloride (99%ee)
(R)-(-)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetyl chloride, 98+%
(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE
(+)-MTPA-CL
(+)-MOSHER'S ACID CHLORIDE
(+)-MOSHER'S CHLORIDE
(S)-(+)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETYL CHLORIDE
(S)-(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)BENZENEACETYLCHLORIDE
(S)-(-)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
(S)-(+)-ALPHA-METHOXY-ALPHA-TRIFLUOROMETHYLPHENYLACETYL CHLORIDE
(S)-(+)-MTPA-CL
(S)-(+)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYL ACETYL CHLORIDE
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoyl chloride
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L) [for Determination of the optical purity of Alcohols and Amines]
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines]
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 99%, 18wt.% solution in dichloromethane
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid chloride
(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl Chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L)[for Determination of the optical purity of Alcohols and Amines]
(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl Chloride [for Determination of the optical purity of Alcohols and Amines]
(-)-α-Methoxy-α-(trifluoromethyl)phenylacetylChloride[forDeterminationoftheopticalpurityofAlcoholsandAmines]>
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride, 99%, n20D:1.4680 - 1.4700
Benzeneacetyl chloride, α-methoxy-α-(trifluoromethyl)-, (αR)-
(R)-(-)-a-Methoxy-a-trifluoromethylphenylacetyl chloride (ca. 18% in Dichloromethane, ca. 1.0mol/L)
(R)-(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl chloride
(-)-α-Methoxy-α-(trifluoromethyl)phenylacetyl Chloride
(R)-(-)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetyl ch