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Quinestrol

CAS No.
152-43-2
Chemical Name:
Quinestrol
Synonyms
eston;eecpe;w3566;EE2CPE;qui-lea;estrovis;plestrovis;QUINESTROL;estrovister;estrovis4000
CBNumber:
CB6189992
Molecular Formula:
C25H32O2
Molecular Weight:
364.52
MDL Number:
MFCD00079189
MOL File:
152-43-2.mol
MSDS File:
SDS
Last updated:2023-11-01 18:37:15

Quinestrol Properties

Melting point 107-108°
alpha D25 +5° (c = 0.5 in dioxane)
Boiling point 435.69°C (rough estimate)
Density 1.0693 (rough estimate)
refractive index 1.4480 (estimate)
storage temp. 2-8°C
solubility Chloroform (Slightly), Dioxane (Slightly), DMSO (Slightly), Methanol (Slightly)
pka 13.10±0.40(Predicted)
form Solid
color White to Off-White
Merck 14,8055
CAS DataBase Reference 152-43-2(CAS DataBase Reference)
FDA UNII JR0N7XD5GZ

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS07,GHS08
Signal word  Danger
Hazard statements  H302+H312+H332-H350-H360
Precautionary statements  P201-P280-P301+P312-P302+P352+P312-P304+P340+P312-P308+P313
Hazard Codes  T
Risk Statements  45-61-20/21/22-46
Safety Statements  53-22-36/37/39-45
WGK Germany  3
RTECS  RC8948000
NFPA 704
0
3 0

Quinestrol price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich E7887 17α-Ethynylestradiol 3-cyclopentyl ether 152-43-2 100mg $60.5 2024-03-01 Buy
Sigma-Aldrich PH001408 3-(CYCLOPENTYLOXY)-17-ETHYNYLESTRA-1(10),2,4-TRIEN-17-OL AldrichCPR 152-43-2 1MG $81.6 2023-06-20 Buy
Cayman Chemical 10006320 Quinestrol ≥98% 152-43-2 100mg $36 2024-03-01 Buy
Cayman Chemical 10006320 Quinestrol ≥98% 152-43-2 250mg $84 2024-03-01 Buy
Cayman Chemical 10006320 Quinestrol ≥98% 152-43-2 500mg $155 2024-03-01 Buy
Product number Packaging Price Buy
E7887 100mg $60.5 Buy
PH001408 1MG $81.6 Buy
10006320 100mg $36 Buy
10006320 250mg $84 Buy
10006320 500mg $155 Buy

Quinestrol Chemical Properties,Uses,Production

Description

Quinestrol is a synthetic estrogen that is effective in hormone replacement therapy. It is a 3-cyclopentyl ether of ethynyl estradiol. After gastrointestinal absorption, it is stored in adipose tissue, where it is slowly released and metabolized in the liver to its active form, ethinyl estradiol. Quinestrol has found limited use in suppressing lactation in postpartum women and, in combination with synthetic progestogens, as contraceptive therapy, although additional studies are needed for both applications.

Uses

antibacterial, antimycoplasmal, isoleucyl-tRNA synthetase inhibitor

Uses

Quinestrol is an estrogen-like compound.

Definition

ChEBI: Quinestrol is a 17-hydroxy steroid and a terminal acetylenic compound. It has a role as a xenoestrogen. It is functionally related to a 17beta-estradiol.

brand name

Estrovis (Parke-Davis).

References

[1]. baumgardner sb, condrea h, daane ta, et al. replacement estrogen therapy for menopausal vasomotor flushes. comparison of quinestrol and conjugated estrogens. obstet gynecol. 1978 apr;51(4):445-52.
[2]. skouby, s.o. criteria for the selection of an optimal estrogen replacement. gynecological endocrinology 15, 60-67 (2001).
[3]. li j, chen f, li c,et al. quinestrol induces spermatogenic apoptosis in vivo via increasing pro-apoptotic proteins in adult male mice. tissue cell. 2014 oct;46(5):318-25.
[4]. li j, chen f, chen y, et al. mitochondrial- and fas-l-mediated pathways involved in quinestrol induced spermatogenic apoptosis in adult rat testes. toxicol mech methods. 2014 dec;24(9):609-15.

Quinestrol Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 123)Suppliers
Supplier Tel Email Country ProdList Advantage
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Nantong Guangyuan Chemicl Co,Ltd
+undefined17712220823 admin@guyunchem.com China 616 58
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
SHANDONG ZHI SHANG CHEMICAL CO.LTD
+86 18953170293 sales@sdzschem.com China 2931 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
HANGZHOU CLAP TECHNOLOGY CO.,LTD
86-571-88216897,88216896 13588875226 sales@hzclap.com CHINA 6313 58
AFINE CHEMICALS LIMITED
0571-85134551 info@afinechem.com CHINA 15377 58
InvivoChem
+1-708-310-1919 +1-13798911105 sales@invivochem.cn United States 6393 58

View Lastest Price from Quinestrol manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Quinestrol pictures 2024-03-08 Quinestrol
152-43-2
US $10.00 / kg 1kg 99% 1000kg Nantong Guangyuan Chemicl Co,Ltd
Quinestrol pictures 2023-11-01 Quinestrol
152-43-2
US $0.00-0.00 / g 1g 98.0% 100kg Hangzhou ICH Biofarm Co., Ltd
Quinestrol pictures 2019-12-20 Quinestrol
152-43-2
US $1.00 / g 100ASSAYS 99% KG/T Career Henan Chemical Co
  • Quinestrol pictures
  • Quinestrol
    152-43-2
  • US $10.00 / kg
  • 99%
  • Nantong Guangyuan Chemicl Co,Ltd
  • Quinestrol pictures
  • Quinestrol
    152-43-2
  • US $0.00-0.00 / g
  • 98.0%
  • Hangzhou ICH Biofarm Co., Ltd
  • Quinestrol pictures
  • Quinestrol
    152-43-2
  • US $1.00 / g
  • 99%
  • Career Henan Chemical Co
17-alpha-ethinylestradiol3-cyclopentylether 3-(cyclopentyloxy)-(17-alpha)-19-norpregna-5(10)-trien-20-yn-17-ol 3-(cyclopentyloxy)-19-nor-17-alpha-pregna-1,3,5(10)-trien-20-yn-17-ol 5(10)-trien-20-yn-17-ol,3-(cyclopentyloxy)-19-nor-17-alpha-pregna-3 eecpe eston 17ALPHA-ETHYLNYL-1,3,5[10]ESTRATRIENE-3,17BETA-DIOL 3-CYCLOPENTYL ETHER 17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether 17a-ethynylestradiol 3-cyclopentyl ether (17ALPHA-3-(CYCLOPENTYLOXY)-19-NORPREGNA-1,3,5(10)TRIENE-20-YN-17-OL 17α-Ethynylestradiol 3-cyclopentyl ether Quinestrol, 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether 17a-Ethynylestradiol 3-cyclopentyl ether17a-ethynyl-1,3,5(10)-estratriene-3,17b-diol 3-cyclopentyl ether 19-Nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol, 3-(cyclopentyloxy)- 3-(Cyclopentyloxy)-19-nor-17a-pregna-1,3,5(10)-trien-20-yn-17-ol
3-Cyclopentyloxy-17a-ethynyl-1,3,5(10)-estratrien-17-ol Ethynylestradiol-3-cyclopentyl ether (17R)-3-(Cyclopentyloxy)-19-norpregna-1,3,5(10)-trien-20-yn-17-ol (8R,9S,13S,14S,17R)-3-(cyclopentoxy)-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol (8R,9S,13S,14S,17R)-3-cyclopentyloxy-17-ethynyl-13-methyl-7,8,9,11,12,14,15,16-octahydro-6H-cyclopenta[a]phenanthren-17-ol 17ALPHA-ETHYNYL-1,3,5(10)-ESTRATRIENE-3,17BETA-DIOL 3-CYCLOPENTYL ETHER 3-cyclopentyloxy-17-alpha-ethynyloestra-1,3,5(10)-trien-17-beta-ol 17α-Ethynyl-1,3,5(10)-estratriene-3,17β-diol 3-cyclopentyl ether estradiol-17-beta3-cyclopentylether estrovis estrovis4000 estrovister plestrovis qui-lea w3566 QUINESTROL 17ALPHA-ETHYNYLESTRADIOL-3-CYCLOPENTYL ETHER EE2CPE Ethinylestradiol 3-cyclopentyl ether 8-cyclopentyloxy-1-ethynyl-12a-methyl-2,3,4,4a,4b,5,6,10b,11,12-decahydrochrysen-1-ol Quinestrol > Quinestrol Quinestrol 19-Norpregna-1,3,5(10)-trien-20-yn-17-ol, 3-(cyclopentyloxy)-, (17α)- QUINESTROL 152-43-2 Quinestrol (W-3566) 152-43-2 C25H32O2 BACTROBAN