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N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide structure

CAS No.: 301675-24-1

Chemical Name:: N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide

Synonyms: IRAK-4 protein kinase inhibitor 2;Benzamide, N-1H-benzimidazol-2-yl-3-nitro-;3-nitro-N-(1H-benzoimidazol-2-yl)-benzamide;N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide;N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide-2;Inhibitor,inhibit,IRAK-4,interleukin-1,IRAK-4 protein kinase inhibitor 2,immune,IRAK 4 protein kinase inhibitor 2,IRAK,Interleukin-1 receptor associated kinase,inflammatory,IL-1,IL-1R associated kinase,IRAK4 protein kinase inhibitor 2

CBNumber:: CB62624242

Molecular Formula:: C14H10N4O3

Molecular Weight:: 282.2542

MDL Number:: MFCD01006950

MOL File:: 301675-24-1.mol

Last updated:2023-09-04 15:51:00

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N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide Properties

storage temp.	Store at -20°C
solubility	DMSO : 10 mg/mL (35.43 mM; Need ultrasonic)

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide price

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
ChemScene	CS-M1436	IRAK-4proteinkinaseinhibitor2	301675-24-1	1g	$275	2021-12-16	Buy

Product number	Packaging	Price	Buy
CS-M1436	1g	$275	Buy

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide Chemical Properties,Uses,Production

Biological Activity

IRAK-4 protein kinase inhibitor 2 (compound 1) is a potent inhibitor of interleukin-1 (IL-1) receptor-associated kinase-4 (IRAK-4), with an IC50 of 4 μM. IRAK-4 protein kinase inhibitor 2 can be used for the research of inflammatory and immune-related conditions or disorders[1]. IRAK-4 protein kinase inhibitor 2 (compound 1) also inhibits IRAK-1, with an IC50 of <10 μM[1].

References

[1]. Powers JP, et, al. Discovery and initial SAR of inhibitors of interleukin-1 receptor-associated kinase-4. Bioorg Med Chem Lett. 2006 Jun 1;16(11):2842-5.

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide Preparation Products And Raw materials

Raw materials

Preparation Products

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide Suppliers

Global( 19)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
TargetMol Chemicals Inc.	+1-781-999-5354	support@targetmol.com	United States	19973	58
Aladdin Scientific	+1-+1(833)-552-7181	sales@aladdinsci.com	United States	52927	58
Haoyuan Chemexpress Co., Ltd.	021-58950125	info@chemexpress.com	China	7553	61
Cool Pharm, Ltd	021-60455363 18019463053	sales@coolpharm.com	China	12357	58
SPIRO PHARMA		eric_feng1954@126.com	China	9254	55
Tianjin Kailiqi Biotechnology Co., Ltd.	15076683720	klq@cw-bio.com	China	3500	55
Shanghai silk sail pharmaceutical technology co., LTD	18916696128	service@snowpharm.com	China	1369	58
Shandong Jirun Biomedical Technology Co., Ltd.	0539-0539-8613587 17661611089	2639273505@qq.com	China	163	58
Energy Chemical	021-58432009 400-005-6266	marketing1@energy-chemical.com	China	44843	58
Jinan Jiuli Biotechnology Co. , Ltd.	2717893647 14768611851	486064515@qq.com	China	1438	58

Supplier	Advantage
TargetMol Chemicals Inc.	58
Aladdin Scientific	58
Haoyuan Chemexpress Co., Ltd.	61
Cool Pharm, Ltd	58
SPIRO PHARMA	55
Tianjin Kailiqi Biotechnology Co., Ltd.	55
Shanghai silk sail pharmaceutical technology co., LTD	58
Shandong Jirun Biomedical Technology Co., Ltd.	58
Energy Chemical	58
Jinan Jiuli Biotechnology Co. , Ltd.	58

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide Spectrum

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide(301675-24-1)¹HNMR

N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide N-(1H-benzo[d]iMidazol-2-yl)-3-nitrobenzaMide-2 3-nitro-N-(1H-benzoimidazol-2-yl)-benzamide Benzamide, N-1H-benzimidazol-2-yl-3-nitro- IRAK-4 protein kinase inhibitor 2 Inhibitor,inhibit,IRAK-4,interleukin-1,IRAK-4 protein kinase inhibitor 2,immune,IRAK 4 protein kinase inhibitor 2,IRAK,Interleukin-1 receptor associated kinase,inflammatory,IL-1,IL-1R associated kinase,IRAK4 protein kinase inhibitor 2 301675-24-1