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D-AMPHETAMINE HYDROCHLORIDE

CAS No.
51-64-9
Chemical Name:
D-AMPHETAMINE HYDROCHLORIDE
Synonyms
Dexamfetamine;D-AMPHETAMINE;Dexedrine;(S)-1-phenylpropan-2-amine;Dexamphetamine;C07884;Dexacaps;dexidrine;NSC-73713;amphetamine(d)
CBNumber:
CB6266202
Molecular Formula:
C9H13N
Molecular Weight:
135.21
MDL Number:
MFCD01708025
MOL File:
51-64-9.mol
Last updated:2024-03-19 15:37:51

D-AMPHETAMINE HYDROCHLORIDE Properties

Melting point 25°C
Boiling point 208.93°C (estimate)
Density 0.9354 (estimate)
refractive index 1.5087 (estimate)
Flash point 9℃
storage temp. -20°C
pka pKa 9.90 (Uncertain)
color Oil
FDA UNII TZ47U051FI
NCI Drug Dictionary Dexedrine
ATC code N06BA02
EPA Substance Registry System Dextroamphetamine (51-64-9)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictogramsGHS hazard pictograms
GHS02,GHS06,GHS08
Signal word  Danger
Hazard statements  H225-H301+H311+H331-H370
Precautionary statements  P210-P260-P280-P301+P310-P311
Hazard Codes  F,T
Risk Statements  11-23/24/25-39/23/24/25
Safety Statements  16-36/37-45
RIDADR  3249
WGK Germany  1
HazardClass  6.1(a)
PackingGroup  II
Toxicity LD50 orl-rat: 38 mg/kg TXAPA9 18,185,71

D-AMPHETAMINE HYDROCHLORIDE Chemical Properties,Uses,Production

Uses

CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake. Controlled substance (stimulant)

Definition

ChEBI: A 1-phenylpropan-2-amine that has S configuration.

brand name

Dexampex (Teva); Dexedrine (GlaxoSmithKline); Dextrostat (Shire); Ferndex (Ferndale);Adiparthrol;Afatin;Amfe-dyn;Amphaetex;Bipheramine;Curban;D-amfetasul;Dexadrine;Dexamed;Dexedrina;Dexten;Dextro-profetamine;Drinamyl;Durophet-m;Maxiton;Mephadexamine-r;Mephadexamin-r;Obetrol;Obotan;Proptan;Robese;Simpamina d;Steladex;Stil-2;Synatan.

World Health Organization (WHO)

Schedule II of the 1971 Convention on Psychotropic Substances. See WHO comment for amfetamine. (Reference: (UNCPS2) United Nations Convention on Psychotropic Substances (II), , , 1971)

Safety Profile

Poison by ingestion, subcutaneous, intravenous, and intraperitoneal routes. Experimental reproductive effects. Chronic exposure causes central nervous system damage and blood-pressure effects. When heated to decomposition it emits toxic NOx. See other amphetamine entries.

Synthesis

The compound can be prepared by optical resolution of amphetamineor directly from (-)-norephedrine by conversion to the (+)-chloroamine followed by catalytic hydrogenation .
Synthesis_51-64-9

D-AMPHETAMINE HYDROCHLORIDE Preparation Products And Raw materials

Raw materials

Preparation Products

DEXTRO-AMPHETAMINE D-AMPHETAMINE HYDROCHLORIDE C07884 S(+)-Amphetamine, 1.0 mg/mL (aS)-a-Methyl-benzeneethanamine d-a-Methylphenethylamine DELTA-AMPHETAMINE S(+)-Amphetamine (dextro-Amphetamine) +/- AMPHETAMINE (5 AMPS/PKGE) S(+)-Amphetamine (dextro-Amphetamine) solution (-)-alpha-Phenylpropylamine (S)-(+)-beta-Phenylisopropylamine alpha-Methylphenethylamine, d-form alpha-methylphenethylamine,d-form amphetamine(d) Amphetamine, (d) Benzeneethanamine, alpha-methyl-, (S)- component of Amodex component of Biphetamine D-(S)-amphetamine D-1-Phenyl-2-aminopropan D-1-Phenyl-2-aminopropane D-2-Amino-1-phenylpropane D-alpha-methylphenethylamine Dexacaps dexidrine NSC-73713 Phenethylamine, alpha-methyl-, d- Phenethylamine, D-alpha-methyl- (S)-AMPHETAMINE S(+)-AMPHETAMINE KWTSXDURSIMDCE-QMMMGPOBSA-N D-Amphetamine Solution, 100ppm Benzeneethanamine, α-methyl-, (αS)- D-AMPHETAMINE HYDROCHLORIDE USP/EP/BP D-AMPHETAMINE Dexamfetamine Dexamphetamine Dexedrine (S)-1-phenylpropan-2-amine (2S)-1-phenylpropan-2-amine 51-64-9 Amines Chiral Reagents Intermediates & Fine Chemicals Pharmaceuticals