ChemicalBook >> CAS DataBase List >>(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate

CAS No.
196085-84-4
Chemical Name:
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate
Synonyms
Atorvastatin Impurity Z;Atorvastatin Impurity 61;Atorvastatin calcium impurity 45;Atorvastatin A8 intermediate 4R6S Diastereomer;Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer;(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate;tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate;(4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester;1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)-
CBNumber:
CB62664118
Molecular Formula:
C14H23NO4
Molecular Weight:
269.34
MDL Number:
MFCD22690693
MOL File:
196085-84-4.mol

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Properties

Boiling point 364.1±17.0 °C(Predicted)
Density 1.016±0.06 g/cm3(Predicted)
storage temp. 2-8°C

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC C981895 (4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-aceticAcidtert-ButylEster 196085-84-4 10mg $155 2021-12-16 Buy
American Custom Chemicals Corporation CCH0033545 TERT-BUTYL-2-((4R,6S)-6-(CYANOMETHYL)-2,2-DIMETHYL-1,3-DIOXAN-4-YL)ACETATE 95.00% 196085-84-4 5MG $503.73 2021-12-16 Buy
Alichem 196085844 tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 196085-84-4 1g $2520 2021-12-16 Buy
Crysdot CD11171218 tert-Butyl2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate 95+% 196085-84-4 1g $2972 2021-12-16 Buy
Product number Packaging Price Buy
C981895 10mg $155 Buy
CCH0033545 5MG $503.73 Buy
196085844 1g $2520 Buy
CD11171218 1g $2972 Buy

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Chemical Properties,Uses,Production

Uses

(4R,6S)-6-(Cyanomethyl)-2,2-dimethyl--1,3-dioxane-4-acetic Acid tert-Butyl Ester is an impurity in the synthesis of Atorvastatin (A791750), a selective, competitive HMG-CoA reductase . Atorvastatin is the only drug in its class specfically indicated for lowering both elevated LDL-cholesterol and triglyceinhibitorrides in patients with hypercholesterolemia.

(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 35)Suppliers
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Standardpharm Co. Ltd.
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Hangzhou Huarong Pharm Co., Ltd.
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China National Standard Pharmaceutical Corporation Limited
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LEAPCHEM CO., LTD.
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Beijing Comparison Pharmaceutical Technology Co., Ltd 010-52878169 15701683040 sales@bjcomparison.com China 4713 58
Hubei XinyuanShun Chemical Co., Ltd. 13971561712, 13995564702, 027-50664929 hbeixys2001@163.com China 3123 55
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17993 56
Wuxi Zhongkun Biochemical Technology Co., Ltd. 0510-85629785 18013409632 sales@reading-chemicals.com China 15185 58
Shanghai Kewel Chemical Co., Ltd. 021-64609169 18901607656 greensnown@163.com China 9911 50
Jiangsu Aikon Biopharmaceutical R&D co.,Ltd. 025-66113011 18112977050 cb6@aikonchem.com China 16687 50
(4R,6S)-tert-Butyl-6-cyanoMethyl-2,2-diMethyl-1,3-dioxane-4-acetate tert-Butyl 2-((4R,6S)-6-(cyanomethyl)-2,2-dimethyl-1,3-dioxan-4-yl)acetate Atorvastatin Acetonide t-Butyl Ester Side Chain (4R,6S)-Isomer Atorvastatin Impurity 61 Atorvastatin A8 intermediate 4R6S Diastereomer Atorvastatin Impurity Z (4R,6S)-1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester 1,3-Dioxane-4-acetic acid, 6-(cyanomethyl)-2,2-dimethyl-, 1,1-dimethylethyl ester, (4R,6S)- Atorvastatin calcium impurity 45 196085-84-4