N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Properties

Melting point	32°C
Boiling point	175-181 °C0.8 mm Hg(lit.)
Density	1.03 g/mL at 20 °C(lit.)
vapor pressure	1 mm Hg ( 20 °C)
refractive index	n20/D 1.4812(lit.)
Flash point	>230 °F
storage temp.	Store below +30°C.
solubility	DMSO : ≥ 83.3 mg/mL (284.87 mM)
form	clear liquid
pka	14.23±0.20(Predicted)
Specific Gravity	1.013
color	Colorless to Almost colorless
PH	10.4 (10g/l, H2O, 20℃)
Water Solubility	miscible
Merck	14,3599
BRN	1781143
InChIKey	NSOXQYCFHDMMGV-UHFFFAOYSA-N
LogP	-2.08 at 25℃
CAS DataBase Reference	102-60-3(CAS DataBase Reference)
Indirect Additives used in Food Contact Substances	N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE
FDA 21 CFR	177.1680
EWG's Food Scores	1
FDA UNII	Q4R969U9FR
EPA Substance Registry System	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine (102-60-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07

Signal word

Warning

Hazard statements

H319

Precautionary statements

Hazard Codes

Risk Statements

Safety Statements

WGK Germany

3

RTECS

UB5604000

TSCA

Yes

HS Code

29221980

NFPA 704

	0
2		0

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine price More Price(20)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	122262	N,N,N′,N′-Tetrakis(2-Hydroxypropyl)ethylenediamine 98%	102-60-3	1l	$161	2024-03-01	Buy
TCI Chemical	T0781	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T)	102-60-3	25g	$24	2024-03-01	Buy
TCI Chemical	T0781	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine >98.0%(T)	102-60-3	500g	$55	2024-03-01	Buy
Alfa Aesar	L16280	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, 99%	102-60-3	100ml	$28.65	2024-03-01	Buy
Alfa Aesar	L16280	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, 99%	102-60-3	500ml	$86.4	2024-03-01	Buy

Product number	Packaging	Price	Buy
122262	1l	$161	Buy
T0781	25g	$24	Buy
T0781	500g	$55	Buy
L16280	100ml	$28.65	Buy
L16280	500ml	$86.4	Buy

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Chemical Properties,Uses,Production

Description

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine (also known as Quadrol) is a monomer based on ethylenediamine used in the production of polyurethane coatings, adhesives, cosmetics and personal care products. It acts as a chelating agent due to the presence of four hydroxyl groups and as a cross-linking agent due to its two amino groups. It is widely used as a component of polymers and copolymers, especially those designed for UV crosslinked polyurethane polymers, dendritic aminopolymers, conductive polymers, inks and coatings. In addition, Quadrol is also used to produce resins, as well as in the manufacture of surfactants, plasticisers and other chemical products.

Chemical Properties

A clear colorless to pale yellow viscous liquid. N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(Tetrahydroxypropyl ethylenediamine) is a chelating agent that binds with metal ions or metallic compounds, preventing them from adhering to a surface (such as skin, hair, or clothing) or causing contamination, such as in the case of trace amounts of iron.

Uses

sweetener

Uses

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine is used as a solvent and preservative. A component of the bacteria-killing substance in sugarcane, it is very alkaline and may be irritating to the skin and mucous membranes. It might also cause skin sensitization.

Uses

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be used as cross-linking agent and catalyst in the manufacture of urethan foams; in epoxy resin curing; as complexing agent, humectant, emulsifier, plasticizer.

Definition

ChEBI: Tetrakis(2-hydroxypropyl)ethylenediamine is an amino alcohol.

Application

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be used as:
(1) A monomer in the synthesis of covalently cross-linked and amorphous shape memory polyurethane (SMPU) foams that are used in biomedical applications, which includes SMPU actuators for treating ischemic stroke, thrombus removal activated by laser light, self-deployable SMP neuronal electrodes, vascular stents, sutures in microsurgery, ocular implants, bandages, cell manipulation, and cell therapy.
(2) A precursor in the preparation of self-healing CFRPs (carbon fiber reinforced polymer) which are thermally responsive with excellent mechanical properties.
(3) A crosslinking agent to create a hydrogel that is biocompatible and supports the growth of neural cells. Hydrogels are specifically designed to mimic the properties of the extracellular matrix (ECM), in promoting cell proliferation. The purpose of the hydrogel in this context is to act as an extracellular matrix (ECM) substitute, providing a supportive environment for cell growth and guiding cell adhesion and outgrowth.

brand name

Neutrol TE (BASF); Quadrol (BASF).

Flammability and Explosibility

Non flammable

Synthesis

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine can be prepared by the ring-opening addition reaction of ethylenediamine and propylene oxide under the action of a catalyst.

in vitro

Results show that viability of macrophages incubated with Quadrol (N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine) at concentrations of 0.5 mM, 1 mM and 4mM are identical to that for controls. Viability, however, is reduced to 50% of control at concentrations of 16 mM to 32 mM. After four hours, at concentrations of 1 mM and 4 mM, Quadrol produces enhanced spreading of 88% and 80%, respectively, as compared to the control of 28%. Quadrol, at a concentration of 16 mM, shows reduced percentage of spreading of macrophages after four hours. Exposure of macrophages to 1.0 mM or 4.0 mM Quadrol concentrations enhances phagocytic activity, 41% and 57%, respectively, over that of the cells exposed to media alone (34%).

in vivo

On day eight after the implantation, the amount of collagen in the implants of normal mice injected with Quadrol (N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine) exceeds controls by more than 200% (p<0.025). By day 11, the collagen content increases to over 300% higher than controls (p<0.01) and by the end of two weeks after wounding, the time interval typically required for normal and complete wound healing, the collagen accumulated in the implants of the Quadrol-treated mice is about 50% above control (p<0.1). The accumulation of collagen in the implants of Quadrol treated STZ-diabetic mice about 100% above the untreated diabetic control on days 8 to 11. By day 14, the collagen deposition has increased to 200% above the controls (p<0.0 5).

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Preparation Products And Raw materials

Raw materials

Ethylenediamine

Preparation Products

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Suppliers

Global( 303)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Wuhan Pinestone Fortune International Trading Co., Ltd.	+86-027-85615902 +86-13971435335	imp.exp8@fengfan.net	China	29	58
henan kanbei chemical co.,ltd	+undefined-86-1523780-4566 +undefined15237804566	henankanbeichemical@163.com	China	511	58
PT CHEM GROUP LIMITED	+86-85511178 +86-85511178	peter68@ptchemgroup.com	China	35453	58
Wuhan Bright Chemical Co., Ltd	+86-02785804899 +86-15071395570	alice@brightchemical.com.cn	China	93	58
WUHAN JADECHEM INTERNATIONAL TRADE CO.,LTD	+86-83527060 +86-13972901456	sales03@jadechem-intl.com	China	81	58
Wuhan Boyuan Import & Export Co., LTD	+8615175982296	Mike@whby-chem.com	China	974	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12452	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2504	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hefei TNJ Chemical Industry Co.,Ltd.	+86-0551-65418679 +86-18949832763	info@tnjchem.com	China	2989	55

Supplier	Advantage
Wuhan Pinestone Fortune International Trading Co., Ltd.	58
henan kanbei chemical co.,ltd	58
PT CHEM GROUP LIMITED	58
Wuhan Bright Chemical Co., Ltd	58
WUHAN JADECHEM INTERNATIONAL TRADE CO.,LTD	58
Wuhan Boyuan Import & Export Co., LTD	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Tianfu Chemical Co.,Ltd.	55
Hefei TNJ Chemical Industry Co.,Ltd.	55

View Lastest Price from N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-01-08	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine 102-60-3	US $28.00-16.00 / kg	1kg	99.50%	30tons	Wuhan Boyuan Import & Export Co., LTD
2023-11-13	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine 102-60-3	US $0.00 / KG	1KG	99%	50000KG/month	Hebei Mojin Biotechnology Co., Ltd
2023-09-06	N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine 102-60-3	US $0.00-0.00 / KG	50KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
102-60-3
US $28.00-16.00 / kg
99.50%
Wuhan Boyuan Import & Export Co., LTD

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
102-60-3
US $0.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine
102-60-3
US $0.00-0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine Spectrum

N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)MS N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)¹HNMR N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)IR1 N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine(102-60-3)Raman

102-60-3(N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine)Related Search:

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N,N,N'-TRIMETHYLETHYLENEDIAMINE 1-DIETHYLAMINO-2-PROPANOL N,N,N',N'-TETRAKIS(2-HYDROXYETHYL)ETHYLENEDIAMINE N-Methyldipropylamine N,N-Diethylethylenediamine

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N,N,N',N'-Tetrakis(2-hydroxyprop-1-yl)ethane-1,2-diamine Ethylenediamine-N,N,N',N'-tetra-2-propanol 1,1',1'',1'''-(Ethylenedinitrilo)tetra-2-propanol 1,1',1'',1'''-(Ethane-1,2-diylbis(azanetriyl))tetrakis(propan-2-ol) N,N,N'N'-tetra(2-hydropropyl)ethylene diaMine (EDTP) HexaMethylene traMine tra hydroxy propy chlorid N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine N,N,N,N-Tetrakis(2-Hydroxypropyl)Ethylenediamine98% Quadrol Buffer [1M Quadrol-TFA Buffer in Propanol-Water(3/4 v/v, pH9.0)] [Sequenation Reagent] Quadrol Buffer [0.25M Quadrol-TFA Buffer in Propanol-Water (3/4v/v,pH9.5)] [Sequenation Reagent] Quadrol(R) (Ethylenedinitrilo)tetra-2-propanol, Quadrol(R) (Ethylenedinitril)tetra-2-propanol 1-[2-(Bis(2-hydroxypropyl)amino)ethyl-(2-hydroxypropyl)amino]propan-2-ol N,N,N,'N' -tetra(2-hydropropayl) ethylene diamine Quadrol Buffer [1M Quadrol-TFA Buffer in Propanol-Water EDTP ( Q75) 2-Propanol, 1,1,1,1-(1,2-ethanediyldinitrilo)tetrakis- 1,1’,1’’,1’’’-Ethylenedini N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine, N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine Ethylenediamine-N,N,N',N'-tetra-2-propanol for synthesis 1,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-propano 1,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-Propanol 1,1’,1’’,1’’’-(ethylenedinitrilo)tetra-2-propano 1,1’,1’’,1’’’-ethane-1,2-diylbisazanediyl-tetrakis-propan-2-ol 1,1’,1’’,1’’’-ethylenedinitrilotetrapropan-2-ol 1’,1’,1’’,1’’’-(1,2-ethanediyldinitrilo)tetrakis-2-propano adekaquadrol QUADROL BUFFER [SEQUENATION REAGENT][0.25M QUADROL-TFA BUFFER IN N-PROPANOL-WATER (3 4V V,PH9.5)] QUADROL BUFFER [SEQUENATION REAGENT][1M QUADROL-TFA BUFFER IN N-PROPANOL-WATER(3 4 V V PH9.0)] entprol n,n,n1,n1-tetrakis n,n,n1,n1-tetrakis(2-hydroxypropyl)ethylenediamine quadroll tetrakis(2-hydroxypropyl)ethylenediamine Tetrakis-[N-(2-hydroxy-propyl)]-ethylenediamine Tetrakis-N-(2-hydroxy-propyl)-ethane-1,2-diamine Tetrakis-N-(2-hydroxy-propyl)-ethylenediamine QUADROL BUFFER N,N,N',N'-TETRA(2-HYDROXY-PROPYL)ETHYLENEDIAMINE Tetra(3-hydroxypropyl)ethylene diamine ETHYLENEDIAMINE-N,N,N',N'-TETRA-2-PROPANOL (ETHYLENEDINITRILO)TETRA-2-PROPANOL 1,1',1'',1'''-(ETHYLENEDINITRILO)TETRA-2-PROPANOL 1,1',1'',1'''-(ETHYLENEDINITRILO)TETRAKIS(2-PROPANOL) N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)-*ETH YLENEDIAMIN N,N,N',N'-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE EDTP(EDETOL) N;N;N′;N′-TETRAKIS(2-HYDROXYPROPYL)ETHYLENEDIAMINE;EDTP N′-Tetrakis(2-hydroxypropyl)ethylenediamine N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine> ETHYLENEDIAMINE-N,N,N',N'-TETRA-2-PROPAN N,N,N',N'-Tetrakis(2-HydroxypropyL N,N,N',N'-Tetrakis(2-hydroxypropyl)ethylenediamine ISO 9001：2015 REACH N,N,N’N’-tetrakis (2-Hydroxypropyl) ethylenedianmine N,N,N,N-Tetrakis(2-hydroxypropyl)ethylenediamine EDTP ( Q75) Q75 / EDTP Q75 TETRAHYDROXYPROPYL ETHYLENEDIAMINE