Mepivacaine hydrochloride
- CAS No.
- 1722-62-9
- Chemical Name:
- Mepivacaine hydrochloride
- Synonyms
- MEPIVACAINE HCL;Mepivacaine Impurity;Meaverin;Mepident;Optocain;Mepicaton;Chlorocain;Carbocaina;Scandonest;Mepivastesin
- CBNumber:
- CB6302306
- Molecular Formula:
- C15H22N2O.ClH
- Molecular Weight:
- 282.81
- MDL Number:
- MFCD00144738
- MOL File:
- 1722-62-9.mol
| Melting point | 255-257°C (dec.) |
|---|---|
| storage temp. | 2-8°C |
| solubility | H2O: soluble20mg/mL, clear |
| form | powder |
| color | white to beige |
| InChI | InChI=1S/C15H22N2O.ClH/c1-11-7-6-8-12(2)14(11)16-15(18)13-9-4-5-10-17(13)3;/h6-8,13H,4-5,9-10H2,1-3H3,(H,16,18);1H |
| InChIKey | RETIMRUQNCDCQB-UHFFFAOYSA-N |
| SMILES | C1(=C(C)C=CC=C1C)NC(=O)C1CCCCN1C.Cl |
| CAS DataBase Reference | 1722-62-9(CAS DataBase Reference) |
| FDA UNII | 4VFX2L7EM5 |
| NCI Drug Dictionary | mepivacaine hydrochloride |
| EPA Substance Registry System | 2-Piperidinecarboxamide, N-(2,6-dimethylphenyl)-1-methyl-, monohydrochloride (1722-62-9) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Danger | |||||||||
| Hazard statements | H301-H336 | |||||||||
| Precautionary statements | P261-P264-P270-P271-P301+P310-P304+P340+P312 | |||||||||
| Hazard Codes | Xn | |||||||||
| Risk Statements | 22 | |||||||||
| Safety Statements | 22-24/25 | |||||||||
| RIDADR | UN 2811 6.1 / PGIII | |||||||||
| RTECS | TK6475000 | |||||||||
| HS Code | 29333990 | |||||||||
| Toxicity | LD50 in mice, rats (mg/kg): 280, 500 s.c. (Aberg) | |||||||||
| NFPA 704 |
|
Mepivacaine hydrochloride price More Price(17)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML1444 | (±)-Mepivacaine hydrochloride ≥98% (HPLC) | 1722-62-9 | 50mg | $156 | 2024-03-01 | Buy |
| Sigma-Aldrich | 1387002 | Mepivacaine hydrochloride United States Pharmacopeia (USP) Reference Standard | 1722-62-9 | 200mg | $436 | 2024-03-01 | Buy |
| TCI Chemical | M2560 | Mepivacaine Hydrochloride >98.0%(HPLC)(T) | 1722-62-9 | 1g | $152 | 2024-03-01 | Buy |
| TCI Chemical | M2560 | Mepivacaine Hydrochloride >98.0%(HPLC)(T) | 1722-62-9 | 5g | $527 | 2024-03-01 | Buy |
| Sigma-Aldrich | PHR1955 | Mepivacaine hydrochloride Pharmaceutical Secondary Standard; Certified Reference Material | 1722-62-9 | 500mg | $214 | 2024-03-01 | Buy |
Mepivacaine hydrochloride Chemical Properties,Uses,Production
Chemical Properties
White Solid
Uses
Mepivacaine hydrochloride may be used as a pharmaceutical reference standard for the determination of the analyte in pharmaceutical formulations by chromatography.
Uses
An anti-inflammatory and analgesic
Uses
anesthetic (local)
Definition
ChEBI: The hydrochloride salt of mepivacaine. It is used as a local anaesthetic.
brand name
Arestocaine Hydrochloride (Solvay Pharmaceuticals); Carbocaine (Hospira); Isocaine Hydrochloride(Novocol); Polocaine (AstraZeneca); Polocaine (Dentsply); Scandonest (Deproco).
Biological Functions
Mepivacaine hydrochloride (Carbocaine) is longer acting than lidocaine and has a more rapid onset of action (3–5 minutes). Topical application is not effective. It has been widely used in obstetrics, but its use has declined recently because of the early transient neurobehavioral effects it produces. Adverse reactions associated with mepivacaine are generally similar to those produced by other local anesthetics. It can be used with epinephrine or levonordefrin (dental use only).
General Description
Pharmaceutical secondary standards for application in quality control, provide pharma laboratories and manufacturers with a convenient and cost-effective alternative to the preparation of in-house working standards. Mepivacaine hydrochloride is a local anesthetic that is related chemically and pharmacologically to the amide-type local anesthetics. It is often administered via local infiltration, peripheral nerve block, etc.
Biochem/physiol Actions
Local anesthetic. Reversibly blocks transient Na+ inward current, as well as the steady-state K+ outward current. Blocks tandem pore (TASK) and Kv1.5, potassium channels in model systems.
Safety Profile
skin irritant. Questionable carcinogen with
Mepivacaine hydrochloride Preparation Products And Raw materials
Raw materials
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | info@pharmachemm.com | China | 241 | 58 |
| Wuhan Haorong Biotechnology Co.,ltd | +8618565342920 | sales@chembj.net | China | 269 | 58 |
| Firsky International Trade (Wuhan) Co., Ltd | +8615387054039 | admin@firsky-cn.com | China | 436 | 58 |
| shandong perfect biotechnology co.ltd | +86-53169958659; +8618596095638 | sales@sdperfect.com | China | 294 | 58 |
| Henan Tengmao Chemical Technology Co. LTD | +8615238638457 | salesvip2@hntmhg.com | China | 415 | 58 |
| Henan Bao Enluo International TradeCo.，LTD | +86-17331933971 +86-17331933971 | deasea125996@gmail.com | China | 2503 | 58 |
| Xiamen Wonderful Bio Technology Co., Ltd. | +8613043004613 | Sara@xmwonderfulbio.com | China | 305 | 58 |
| Hebei Xinsheng New Material Technology Co., LTD. | +86-16632316109 | xinshengkeji@xsmaterial.com | China | 1100 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Sigma Audley | +86-18336680971 +86-18126314766 | nova@sh-teruiop.com | China | 525 | 58 |
View Lastest Price from Mepivacaine hydrochloride manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-04-24 | Mepivacaine hydrochloride
1722-62-9
|
US $0.00-0.00 / kg | 1kg | 99% | 500 | Wuhan Haorong Biotechnology Co.,Ltd | |
 |
2024-04-15 | Mepivacaine hydrochloride
1722-62-9
|
US $1.00 / mg | 1000mg | 99 | 5ton/month | ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD | |
 |
2024-04-12 | Mepivacaine hydrochloride
1722-62-9
|
US $3.00-1.00 / kg | 1kg | 99.9% | 10 tons | Shanghai Aosiris new Material Technology Co., LTD |
-
- Mepivacaine hydrochloride
1722-62-9
- US $0.00-0.00 / kg
- 99%
- Wuhan Haorong Biotechnology Co.,Ltd
-
- Mepivacaine hydrochloride
1722-62-9
- US $1.00 / mg
- 99
- ANHUI SHENGZHIKAI BIOTECHNOLOGY CO.,LTD
-
- Mepivacaine hydrochloride
1722-62-9
- US $3.00-1.00 / kg
- 99.9%
- Shanghai Aosiris new Material Technology Co., LTD