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2-Bromoacetophenone

2-Bromoacetophenone structure

CAS No.: 70-11-1

Chemical Name:: 2-Bromoacetophenone

Synonyms: PHENACYL BROMIDE;2-BROMO-1-PHENYLETHANONE;A-BROMOACETOPHENONE;1-Phenyl-2-broMoethanone;NSC 9807;Stauffer 4644;AKOS BBS-00004003;Bromoacetylbenzene;-Bromoacetophenone;PhenacylBromide>

CBNumber:: CB6305185

Molecular Formula:: C8H7BrO

Molecular Weight:: 199.04

MDL Number:: MFCD00000195

MOL File:: 70-11-1.mol

MSDS File:: SDS

Last updated:2023-10-13 20:07:10

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2-Bromoacetophenone Properties

Melting point	48-51 °C (lit.)
Boiling point	135 °C/18 mmHg (lit.)
Density	1.476
refractive index	1.5700 (estimate)
Flash point	>230 °F
storage temp.	2-8°C
solubility	Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly)
form	Crystals or Powder
color	White to dark green-brown
Water Solubility	PRACTICALLY INSOLUBLE
Merck	14,1402
BRN	606474
Stability	Stable. Incompatible with strong bases, strong oxidizing agents. Combustible.
InChIKey	LIGACIXOYTUXAW-UHFFFAOYSA-N
CAS DataBase Reference	70-11-1(CAS DataBase Reference)
FDA UNII	754Y0U325I
NIST Chemistry Reference	Ethanone, 2-bromo-1-phenyl-(70-11-1)
EPA Substance Registry System	Ethanone, 2-bromo-1-phenyl- (70-11-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS05

Signal word

Danger

Hazard statements

H314

Precautionary statements

P260-P280-P303+P361+P353-P304+P340+P310-P305+P351+P338-P363

Hazard Codes

Risk Statements

34-20/21/22

Safety Statements

26-36/37/39-45

RIDADR

UN 2645 6.1/PG 2

WGK Germany

8-19

Hazard Note

Corrosive

TSCA

Yes

HazardClass

6.1

PackingGroup

HS Code

29143990

NFPA 704

	1
3		0

2-Bromoacetophenone price More Price(46)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	115835	2-Bromoacetophenone 98%	70-11-1	5g	$39.2	2024-03-01	Buy
Sigma-Aldrich	115835	2-Bromoacetophenone 98%	70-11-1	100g	$92.5	2024-03-01	Buy
TCI Chemical	A5508	Phenacyl Bromide [for HPLC Labeling] >98.0%(HPLC)(T)	70-11-1	5g	$31	2024-03-01	Buy
TCI Chemical	B0535	Phenacyl Bromide >98.0%(GC)	70-11-1	25g	$56	2024-03-01	Buy
Alfa Aesar	A15576	2-Bromoacetophenone, 98%	70-11-1	25g	$37.6	2023-06-20	Buy

Product number	Packaging	Price	Buy
115835	5g	$39.2	Buy
115835	100g	$92.5	Buy
A5508	5g	$31	Buy
B0535	25g	$56	Buy
A15576	25g	$37.6	Buy

2-Bromoacetophenone Chemical Properties,Uses,Production

Chemical Properties

Off white-grey green crystaline powder

Uses

It is used in preparation of crystalline esters from acids. 2-Bromoacetophenone is a complete and irreversible inactivator of human liver aldehyde dehydrogenase isoenzymes E1 and E2.

Uses

2-Bromoacetophenone is a brominated acteophenone derivative. 2-Bromoacetophenone has been shown to completely and irreversibly inactivate human liver aldehyde dehydrogenase (EC 1.2.1.3) isoenzymes E1 and E2. 2-Bromoacetophenone and its derivatives display some inhibitory activity on neutral protein tyrosine.inhibitors

Definition

ChEBI: An alpha-bromoketone that is acetophenone substituted by a bromo group at position 2.

Synthesis Reference(s)

Journal of the American Chemical Society, 76, p. 5796, 1954 DOI: 10.1021/ja01651a061
Organic Syntheses, Coll. Vol. 2, p. 480, 1943
Synthetic Communications, 22, p. 1923, 1992 DOI: 10.1080/00397919208021322

General Description

A crystalline solid or a liquid with a sharp odor. Toxic by inhalation, ingestion and skin absorption. A severe eye irritant (a lachrymator). Used to make other chemicals.

Air & Water Reactions

Reacts slowly with moisture in air to form hydrogen bromide.

Reactivity Profile

2-Bromoacetophenone reacts slowly with metals causing mild corrosion.

Health Hazard

TOXIC; inhalation, ingestion or skin contact with material may cause severe injury or death. Contact with molten substance may cause severe burns to skin and eyes. Avoid any skin contact. Effects of contact or inhalation may be delayed. Fire may produce irritating, corrosive and/or toxic gases. Runoff from fire control or dilution water may be corrosive and/or toxic and cause pollution.

Fire Hazard

Combustible material: may burn but does not ignite readily. When heated, vapors may form explosive mixtures with air: indoors, outdoors and sewers explosion hazards. Contact with metals may evolve flammable hydrogen gas. Containers may explode when heated. Runoff may pollute waterways. Substance may be transported in a molten form.

Purification Methods

Crystallise the bromide from EtOH, MeOH or pet ether (b 80-100o). [Tanner J Org Chem 52 2142 1987, Beilstein 7 IV 649.]

2-Bromoacetophenone Preparation Products And Raw materials

Raw materials

Acetone Bromobenzene Government regulation

Preparation Products

A-BROMO-4-NITROACETOPHENONE HEXAMINE 1-[2-(4-CHLOROPHENYL)-1-(1-HYDROXY-1-PHENYLETHYL)ETHYL]-1,2,4-TRIAZOLE 3-(-Hydroxyphenethyl)-2-imino thiazolidine 4-PHENYL-1,2,3-THIADIAZOL-5-AMINE DIETHOXYMETHANE

1-Phenacylpyridinium bromide 5-AMINO-3-PHENYLISOXAZOLE 4-AMINO-ALPHA-TERT-BUTYLAMINE-3,5-DICHLOROACETOPHENONE 2-(2-iminothiazolidin-3-yl)-1-phenylethan-1-one monohydrobromide 4-Acetyloxy-3-acetyloxymethyl-(N-benzyl-N-tertbutylamino)acetophenone hydrochloride

1-Propanone, 3-hydroxy-1,3-diphenyl- 2-Phenylindole N-[1-(hydroxymethyl)-2-(4-nitrophenyl)-2-oxoethyl]acetamide levophenacylmorphan (R)-Styrene oxide

Benzoic acid, 2-ethenyl- (9CI) 2-Aminoacetophenone hydrochloride 4,6-DIPHENYL-2-PYRONE R-4-Boc-2-phenylpiperazine

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2-Bromoacetophenone Suppliers

Global( 348)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Shanghai Daken Advanced Materials Co.,Ltd	+86-371-66670886	info@dakenam.com	China	15928	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21691	55
ATK CHEMICAL COMPANY LIMITED	+undefined-21-51877795	ivan@atkchemical.com	China	32480	60
Hubei Jusheng Technology Co.,Ltd.	18871490254	linda@hubeijusheng.com	CHINA	28180	58
Hubei xin bonus chemical co. LTD	86-13657291602	linda@hubeijusheng.com	CHINA	22968	58
Shandong chuangyingchemical Co., Ltd.	18853181302	sale@chuangyingchem.com	CHINA	5909	58
Alchem Pharmtech,Inc.	8485655694	sales@alchempharmtech.com	United States	63711	58
Hebei shuoxi biotechnology co. LTD	+8613081092107		CHINA	968	58

Supplier	Advantage
Hebei Yanxi Chemical Co., Ltd.	58
Capot Chemical Co.,Ltd.	60
Shanghai Daken Advanced Materials Co.,Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
ATK CHEMICAL COMPANY LIMITED	60
Hubei Jusheng Technology Co.,Ltd.	58
Hubei xin bonus chemical co. LTD	58
Shandong chuangyingchemical Co., Ltd.	58
Alchem Pharmtech,Inc.	58
Hebei shuoxi biotechnology co. LTD	58

View Lastest Price from 2-Bromoacetophenone manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-01-08	α-Bromoacetophenone 70-11-1	US $30.00-15.00 / KG	10KG	99.50%	100tons	Wuhan Boyuan Import & Export Co., LTD
2023-10-14	2-Bromoacetophenone 70-11-1	US $40.00-40.00 / kg	1kg	0.99	10 tons	Hebei Yanxi Chemical Co., Ltd.
2023-09-06	2-Bromoacetophenone 70-11-1	US $0.00 / KG	1KG	99%	500000kg	Hebei Guanlang Biotechnology Co., Ltd.

α-Bromoacetophenone
70-11-1
US $30.00-15.00 / KG
99.50%
Wuhan Boyuan Import & Export Co., LTD

2-Bromoacetophenone
70-11-1
US $40.00-40.00 / kg
0.99
Hebei Yanxi Chemical Co., Ltd.

2-Bromoacetophenone
70-11-1
US $0.00 / KG
99%
Hebei Guanlang Biotechnology Co., Ltd.

2-Bromoacetophenone Spectrum

2-Bromoacetophenone(70-11-1)MS 2-Bromoacetophenone(70-11-1)¹HNMR 2-Bromoacetophenone(70-11-1)¹³CNMR 2-Bromoacetophenone(70-11-1)IR1 2-Bromoacetophenone(70-11-1)IR2 2-Bromoacetophenone(70-11-1)IR3

70-11-1(2-Bromoacetophenone)Related Search:

2',4'-Dichloroacetophenone Acetophenone Clidinium bromide 4'-Methoxyacetophenone 4'-Hydroxyacetophenone

Sodium bromate 2-Chloroacetophenone 3-Bromoanisole 3-Aminoacetophenone 3-Nitroacetophenone

4'-Chloroacetophenone Ethidium bromide 4-Nitroacetophenone 2-BROMO-2-PHENYLACETOPHENONE 4'-Bromoacetophenone

Bromine Methyl bromide 3'-Bromoacetophenone

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ω-Bromoacetophenone, Phenacyl bromide 1-(Bromoacetyl)benzene Bromoacetylbenzene roxylamine hydrochloride w-Bromoacetophenone 2-Bromoacetophenone,ω-Bromoacetophenone, Phenacyl bromide 2-Bromoacetophenone ,99% 2-Bromoacetophenone, 2-Bromo-1-phenylethan-1-one Bromomethylphenylketone Ethanone,2-bromo-1-phenyl- Ethanone2-bromo-1-phenyl- omega-Bromacetophenone Stauffer 4644 1-BroMo-2-phenylethan-2-one NSC 9807 2-BROMOACETOPHENONE FOR SYNTHESIS 2-BroMoacetophenone, 98% 100GR 2-BroMoacetophenone, 98% 25GR 2-Bromoacetophenone≥ 97% (GC) Alpha broMine generation of acetophenone OMEGA-BROMOACETOPHENONE TIMTEC-BB SBB002705 A-BROMOACETOPHENONE / PHENACYL BROMIDE 2-Bromoacetophenone Phenacyl Bromide [for HPLC Labeling] 2-Bromoacetophenone omega-Bromoacetophenone 2-Bromo-1-Phenylethanone 2-Bromoacetophenone (Phenacylbromide) 2-Bromoacetophenone98% ALPHA-BROMOACETOPHENONE Phenacyl bromide 98% Acetophenone, 2-bromo- Benzoylmethyl bromide -Bromoacetophenone Bromomethyl phenyl ketone 2-Bromo-1-phenyethanone 2-bromo-1-phenyl-ethanon 2-BROMO-1-PHENYL-1-ETHANONE AKOS BBS-00004003 4-Acetoxy-3-acetoxymethyl-&alpha 3-Carbomethoxy-4-hydroxy-&alpha PhenacylBromide> Phenacyl Bromide [for HPLC Labeling]> 2-BROMO ACETEPHENONE 1-Phenyl-2-broMoethanone PHENACYL BROMIDE A-BROMOACETOPHENONE 2-BROMO-1-PHENYLETHANONE α-Bromoacetophenone Tulobuterol Impurity 8 70-11-1 1970-01-1 70-11-0 25-87-3 710-11-1 C8H7HBrO BrCH2COC6H5 C6H5COCH2Br Building Blocks