ChemicalBook >> CAS DataBase List >>2,2',4,4'-Tetrahydroxybenzophenone

2,2',4,4'-Tetrahydroxybenzophenone

CAS No.
131-55-5
Chemical Name:
2,2',4,4'-Tetrahydroxybenzophenone
Synonyms
BENZOPHENONE-2;TETRAHYDROXYBENZOPHENONE;UV Absorber Benzophenone-2;70A-196;uvinuld-50;Uvinul D-50;Uvinol D-50;Seesorb 106;Sumisorb 150;Sinosorb? BP-2
CBNumber:
CB6344256
Molecular Formula:
C13H10O5
Molecular Weight:
246.22
MDL Number:
MFCD00002278
MOL File:
131-55-5.mol
MSDS File:
SDS
Last updated:2024-03-28 09:55:42

2,2',4,4'-Tetrahydroxybenzophenone Properties

Melting point 198-200 °C(lit.)
Boiling point 349.21°C (rough estimate)
Density 1.216
refractive index 1.4825 (estimate)
storage temp. Sealed in dry,Room Temperature
solubility DMSO (Slightly, Sonicated), Methanol (Slightly)
form Solid
pka 6.98±0.35(Predicted)
color Needles from H2O
Water Solubility Slightly soluble in water.
BRN 1914746
Stability Hygroscopic
InChIKey WXNRYSGJLQFHBR-UHFFFAOYSA-N
LogP 3.091 (est)
CAS DataBase Reference 131-55-5(CAS DataBase Reference)
EWG's Food Scores 4
FDA UNII PRR8K3H9VN
NIST Chemistry Reference 2,2',4,4'-Tetrahydroxybenzophenone(131-55-5)
EPA Substance Registry System 2,2',4,4'-Tetrahydroxybenzophenone (131-55-5)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H317-H319
Precautionary statements  P261-P264-P280-P301+P312-P302+P352-P305+P351+P338
Hazard Codes  Xn,Xi
Risk Statements  22-36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  DJ1892000
TSCA  Yes
HS Code  29145090
Toxicity LD50 oral in rat: 1220mg/kg
NFPA 704
0
2 0

2,2',4,4'-Tetrahydroxybenzophenone price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich T16403 2,2′,4,4′-Tetrahydroxybenzophenone 97% 131-55-5 25g $62.4 2024-03-01 Buy
Sigma-Aldrich T16403 2,2′,4,4′-Tetrahydroxybenzophenone 97% 131-55-5 100g $135 2024-03-01 Buy
TCI Chemical T0118 2,2',4,4'-Tetrahydroxybenzophenone >98.0%(HPLC) 131-55-5 25g $39 2024-03-01 Buy
Alfa Aesar A10237 2,2',4,4'-Tetrahydroxybenzophenone, 98+% 131-55-5 25g $39.65 2024-03-01 Buy
Alfa Aesar A10237 2,2',4,4'-Tetrahydroxybenzophenone, 98+% 131-55-5 100g $108.65 2024-03-01 Buy
Product number Packaging Price Buy
T16403 25g $62.4 Buy
T16403 100g $135 Buy
T0118 25g $39 Buy
A10237 25g $39.65 Buy
A10237 100g $108.65 Buy

2,2',4,4'-Tetrahydroxybenzophenone Chemical Properties,Uses,Production

Application

2,2',4,4'-Tetrahydroxybenzophenone (BZP-2) is water-soluble and light-yellow powder (figure 1). BZP-2 is widely used in perfumes to prevent their degradation due to light. BZP-2 is a UV-absorber that helps protect against product degradation because of UV-light exposure and it is widely used in sunscreens and in cosmetics (figure 2), such as: anti-aging” creams and hair sprays and shampoos, paints and plastics. It can also mask odor associated with a formulation’s composition. In addition, the hypolipemiant drug fenofibrate is also a substituted benzophenone.

Potential Exposure & Risk

Although 2,2',4,4'-Tetrahydroxybenzophenone is used as a UV-blocker in cosmetics, plastics and automotive car products, its safety issue still should be noted. Such as workers that use BZP-2 may breathe in dust or have direct skin contact and the general population may be exposed by dermal contact with products containing this compound.
Skin allergic reaction has been reported in some people using sunscreens or cosmetics containing this compound. 2,2',4,4'-Tetrahydroxybenzophenone(BZP-2) is a member of a group of chemicals known as endocrine disruptors, which may alter the function and/or development of the reproductive system. Limited evidence indicates that exposure to benzophenone UV-absorbing chemicals, including BZP-2, is associated with an altered ratio of males to females at birth (increased females).

Chemical Properties

yellow to brown crystalline powder

Uses

2,2',4,4'-Tetrahydroxybenzophenone is a uV-absorber that helps protect against product degradation because of uV-light exposure. It can also mask odor associated with a formulation’s composition.

Uses

2,2′,4,4′-Tetrahydroxybenzophenone are benzophenone-type UV filters with known or suspected endocrine disrupting properties detected in surface waters, sunscreens, personal care products, clothing and food packaging. It is used to protect the skin and materials from the adverse effects of UV-radiation.

Uses

2,2',4,4'-Tetrahydroxybenzophenone is used as the raw material of ultraviolet absorbers in cosmetics, plastics, resins and rubber. It is used as pharmaceutical intermediates and light-sensitive materials. It is also used as pharmaceutical adjuvant.

Preparation

Obtained (small amount) by melting a fluorescin chloride/sodium hydroxide mixture in the presence of a very few water at 230–240° for 2–3 h.

Contact allergens

BZP-2 is widely used in perfumes to prevent their degradation due to light. It can cause allergic contact dermatitis.

Safety Profile

Moderately toxic by ingestion. Aneye irritant. Mutation data reported. When heated todecomposition it emits toxic fumes of NOx.

3859-65-2
131-55-5
Synthesis of 2,2',4,4'-Tetrahydroxybenzophenone from Triamcinolone 21-acetate

2,2',4,4'-Tetrahydroxybenzophenone Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 490)Suppliers
Supplier Tel Email Country ProdList Advantage
Jinan Qinmu Fine Chemical Co.,Ltd.
+8618660799346 sales@qinmuchem.com China 1009 58
QINGDAO JADE NEW MATERIAL TECNOLOGY CO.,LTD
+86 13658692156 zandrew@jadenmtc.com China 220 58
Qingdao Truelight functional Material Technology Co., Ltd.
+86-13573844393 songjames@truelightchem.com China 219 58
Zhengzhou Anbu Chem Co.,Ltd
+86-0371-88006763; +8615988602810 sales@anbuchem.com China 3000 58
Henan Bao Enluo International TradeCo.,LTD
+86-17331933971 +86-17331933971 deasea125996@gmail.com China 2503 58
Hangzhou ICH Biofarm Co., Ltd
+undefined8613073685410 sales@ichemie.com China 985 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Springchem New Material Technology Co.,Limited
+86-021-62885108 +8613917661608 info@spring-chem.com China 2068 57
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60

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View Lastest Price from 2,2',4,4'-Tetrahydroxybenzophenone manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
2,2',4,4'-Tetrahydroxybenzophenone pictures 2024-04-19 2,2',4,4'-Tetrahydroxybenzophenone
131-55-5
US $5.00 / kg 1kg ≥99% 500mt/year Jinan Finer Chemical Co., Ltd
UV ABSORBER TRUELICHT BP-2 pictures 2024-04-16 UV ABSORBER TRUELICHT BP-2
131-55-5
US $0.00 / KG 1KG 98.0% 20 tons Qingdao Truelight functional Material Technology Co., Ltd.
2,2',4,4'-Tetrahydroxybenzophenone pictures 2024-03-23 2,2',4,4'-Tetrahydroxybenzophenone
131-55-5
US $6.00-0.50 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
2,2,4,4-Tetrahydroxybenzophenol 2,2’,4,4’-tetrahydroxy-benzophenon 2,2’,4,4’-tetrehydroxybenzophenone 2,2,4,4 TETRAHYDROXY BENZOPHENONE 2,4,2',4'-Tetrahydroxybenzophenone 2,4,2’,4’-tetrahydroxybenzophenone Benzophenone, 2,2',4,4'-tetrahydroxy- bis(2,4-dihydroxyphenyl)-methanon Methanone, bis(2,4-dihydroxyphenyl)- Uvinol D-50 Uvinul D-50 uvinuld-50 UV Absorber BP2 2,2',4,4'-Tetrahydroxybenzophenone (UV 246) 2,2',4,4'-TETRAHYDROXYBENZOPHENONE DI(2,4-DIHYDROXYPHENYL)METHANONE BENZOPHENONE-2-(2,2',4,4'-TETRAHYDROXYBENZOPHENONE) BIS-(2,4-DIHYDROXY-PHENYL)-METHANONE 2,2',4,4'-Tetrahydroxybenzophenone(bp-2) TIMTEC-BB SBB003178 2,2',4,4'-Tetrahydroxybenzophe 2.2''-4.4''-TETRAHYD[CL]ROXYBENZOPHENONE 2,2'',4,4''-TETRAHYDROXYBENZOPHENONE 98+% 2,2',4,4'-tetrahydroxy Benzophenone(Benzophenone-2) Seesorb 106 Sumisorb 150 70A-196 2,2',4,4'-Tetrahydroxybenzophenone,97% 4-[(2,4-dihydroxyphenyl)carbonyl]benzene-1,3-diol Benzophenone-2 (2,2'4,4'-Terahydroxy Benzophenone) Benzophenone, 2,2' 2,2',4,4'-tetrahyroxybenzophenone 2,2',4,4'-Tetrahydroxybenzophenone> 2,2’,4,4’-Tetrahydroxybenzophenone Solution in Acetonitrile, 100μg/mL 2,2',4,4'-Tetrahydroxybenzophenone ISO 9001:2015 REACH UV ABSORBER TRUELICHT BP-2 2,2',4,4'-tetrahydroxy Benzophenone,Benzophenone-2(BP-2) High purity CAS 131-55-5 2,2',4,4'-Tetrahydroxybenzophenone in stock BENZOPHENONE-2 TETRAHYDROXYBENZOPHENONE UV Absorber Benzophenone-2 2,2',4,4'-Tetrahydroxybenzop Sinosorb? BP-2 Zolmitriptan Impurity 1-d6 Phloroglucinol Impurity 88 2,2',4,4'-Tetrahydroxybenzophenone 131-55-5 C13H10O5 HO2C6H32CO Ketones Organic Building Blocks Benzophenones (for High-Performance Polymer Research) Reagent for High-Performance Polymer Research Building Blocks C13 to C14 Carbonyl Compounds Building Blocks C13 to C14