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1-Aminocyclopropanecarboxylic acid

1-Aminocyclopropanecarboxylic acid Structure
1-Aminocyclopropanecarboxylic acid structure
CAS No.
22059-21-8
Chemical Name:
1-Aminocyclopropanecarboxylic acid
Synonyms
ACC;1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID;1-AMinocyclopropane-1-carboxylate;Ac3c;H-ACPC-OH;AMinocyclopropanecarboxylic acid;Cyclopropanecarboxylic acid, 1-amino-;Acpc-OH;1,1-ACCP;NSC 98430
CBNumber:
CB6401146
Molecular Formula:
C4H7NO2
Molecular Weight:
101.1
MDL Number:
MFCD00009944
MOL File:
22059-21-8.mol
Last updated:2024-04-08 13:48:25
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1-Aminocyclopropanecarboxylic acid Properties

Melting point 229-231 °C (lit.)
Boiling point 189.47°C (rough estimate)
Density 1.2245 (rough estimate)
refractive index 1.4340 (estimate)
storage temp. Keep in dark place,Sealed in dry,Room Temperature
solubility DMSO (Slightly), Water (Slightly)
pka 2.29±0.20(Predicted)
form Powder and Granules
color White to off-white
Water Solubility Soluble in water.
BRN 2076413
Stability Store in freezer at -20°C
InChIKey PAJPWUMXBYXFCZ-UHFFFAOYSA-N
CAS DataBase Reference 22059-21-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII 3K9EJ633GL

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P264-P280-P302+P352+P332+P313+P362+P364-P305+P351+P338+P337+P313-P261-P280a-P304+P340-P305+P351+P338-P405-P501a
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-37/39
WGK Germany  3
RTECS  GZ1110000
Hazard Note  Irritant
HS Code  29213000
NFPA 704
0
2 0

1-Aminocyclopropanecarboxylic acid price More Price(49)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 149101-M 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. 22059-21-8 250mg $130 2024-03-01 Buy
Sigma-Aldrich 149101-M 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem An agonist for the glycine modulatory site of the N-methyl-D-aspartate (NMDA) receptor complex. 22059-21-8 1g $310 2024-03-01 Buy
TCI Chemical A1178 1-Aminocyclopropanecarboxylic Acid >97.0%(T) 22059-21-8 1g $76 2024-03-01 Buy
TCI Chemical A1178 1-Aminocyclopropanecarboxylic Acid >97.0%(T) 22059-21-8 5g $178 2024-03-01 Buy
Alfa Aesar J65118 1-Amino-1-cyclopropanecarboxylic acid, 98% 22059-21-8 250mg $87.8 2024-03-01 Buy
Product number Packaging Price Buy
149101-M 250mg $130 Buy
149101-M 1g $310 Buy
A1178 1g $76 Buy
A1178 5g $178 Buy
J65118 250mg $87.8 Buy

1-Aminocyclopropanecarboxylic acid Chemical Properties,Uses,Production

Description

1-Aminocyclopropanecarboxylic acid (ACPC) is an intermediate in the synthesis of ethylene, the plant hormone responsible for biological processes ranging from seed germination to organ senescence. ACPC has been shown to modulate NMDA receptor activity by acting as a partial agonist at the glycine-binding site on NMDA receptors (EC50 = 0.7-0.9 μM) in the presence of low levels (1 μM) of glutamate and as a competitive antagonist at the glutamate-binding site on NMDA receptors (EC50 = 81.6 nM) with high levels (10 μM) of glutamate. This compound has been reported to protect against neuron cell death in in vivo models of ischemia by enabling moderate levels of NMDA receptor activation and attenuating any excess NMDA receptor signaling that may lead to neurotoxicity.

Chemical Properties

Crystalline

Uses

1-Aminocyclopropane-1-carboxylic Acid is a plant growth regulator. It is an NMDA agonist acting at the glycine site.

Uses

1-Aminocyclopropane-1-carboxylic Acid is an intermediate in the conversion of methionine to ethylene during the ripening in apples. It also plays an important role in the biosynthesis of the plant hormone ethylene.1-Aminocyclopropane-1-carboxylic Acid is shown to block convulsions and death produced by NMDA exposure, significantly reducing seizure induction and cell death of NMDA-treated hippocampal neurons. 1-Aminocyclopropane-1-carboxylic Acid is produced endogenously in the tomato and other higher plants as a product of the action of 1-aminocyclopropane-1-carboxylic acid synthase in the biosynthesis of ethylene.

Definition

ChEBI: A non-proteinogenic alpha-amino acid consisting of cyclopropane having amino and carboxy substituents both at the 1-position.

Synthesis Reference(s)

Synthetic Communications, 18, p. 141, 1988 DOI: 10.1080/00397918808077338
Synthesis, p. 127, 1984

General Description

1-Aminocyclopropanecarboxylic acid is a member of 1-aminocycloalkanecarboxylic acids.

Biochem/physiol Actions

1-Aminocyclopropanecarboxylic acid (ACC) exhibits anticonvulsant, anxiolytic, anti-addictive, neuroprotective and antidepressant-like effects in rats and mice. ACC does not affect memory or learning processes.

1-Aminocyclopropanecarboxylic acid synthesis

68781-13-5
22059-21-8
Synthesis of 1-Aminocyclopropanecarboxylic acid from 1-Aminocyclopropane-1-carboxylic acid hydrochloride

1-Aminocyclopropanecarboxylic acid Preparation Products And Raw materials

Raw materials

Hexamethylphosphoramide tert-Butyl methyl ether Sodium sulfate Sodium chloride Strong alkaline anion exchange resin
Glycine ethyl ester hydrochloride Triethylamine Diisopropylamine Benzaldehyde 1,2-Dibromoethane
Tetrahydrofuran Diethyl ether Ammonium chloride Hydrochloric acid Sodium bicarbonate
Magnesium sulfate n-Butyllithium

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Preparation Products

1-(Boc-amino)cyclopropanecarboxylic acid

1-Aminocyclopropanecarboxylic acid Suppliers

Global( 472)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Yanxi Chemical Co., Ltd. 		+8617531190177 peter@yan-xi.com China 5993 58
Firsky International Trade (Wuhan) Co., Ltd 		+8615387054039 admin@firsky-cn.com China 436 58
Henan Fengda Chemical Co., Ltd 		+86-371-86557731 +86-13613820652 info@fdachem.com China 7377 58
Capot Chemical Co.,Ltd. 		571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Shanghai Daken Advanced Materials Co.,Ltd 		+86-371-66670886 info@dakenam.com China 15371 58
Henan Tianfu Chemical Co.,Ltd. 		+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21695 55
Nanjing ChemLin Chemical Industry Co., Ltd. 		025-83697070 product@chemlin.com.cn CHINA 3012 60
ATK CHEMICAL COMPANY LIMITED 		+undefined-21-51877795 ivan@atkchemical.com China 32480 60
Zjartschem 		+86-571-8723 8903 jocelynpan@zjarts.com jocelynpan@zjarts.com CHINA 993 58
career henan chemical co 		+86-0371-86658258 sales@coreychem.com China 29914 58
Supplier Advantage
Hebei Yanxi Chemical Co., Ltd. 		58
Firsky International Trade (Wuhan) Co., Ltd 		58
Henan Fengda Chemical Co., Ltd 		58
Capot Chemical Co.,Ltd. 		60
Shanghai Daken Advanced Materials Co.,Ltd 		58
Henan Tianfu Chemical Co.,Ltd. 		55
Nanjing ChemLin Chemical Industry Co., Ltd. 		60
ATK CHEMICAL COMPANY LIMITED 		60
Zjartschem 		58
career henan chemical co 		58

View Lastest Price from 1-Aminocyclopropanecarboxylic acid manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
1-Aminocyclopropanecarboxylic acid pictures 2024-04-08 1-Aminocyclopropanecarboxylic acid
22059-21-8
 US $34.00-1.20 / kg 1kg 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
1-Aminocyclopropanecarboxylic acid pictures 2023-11-15 1-Aminocyclopropanecarboxylic acid
22059-21-8
 US $0.00 / kg 1kg 0.99 20 tons Hebei Yanxi Chemical Co., Ltd.
1-Aminocyclopropane-1-carboxylic acid pictures 2023-10-08 1-Aminocyclopropane-1-carboxylic acid
22059-21-8
 US $30.00 / KG 1KG 99% 20T Firsky International Trade (Wuhan) Co., Ltd

1-Aminocyclopropanecarboxylic acid Spectrum

1-Aminocyclopropanecarboxylic acid(22059-21-8)MS1-Aminocyclopropanecarboxylic acid(22059-21-8)1HNMR1-Aminocyclopropanecarboxylic acid(22059-21-8)IR11-Aminocyclopropanecarboxylic acid(22059-21-8)IR21-Aminocyclopropanecarboxylic acid(22059-21-8)Raman

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1-Aminocyclopropanecarboxylic acid ,97% 1-Amino-1-cyclopropanecarboxylic acid ,98.5% 1-AMinocyclopropanecarbox... 1-AMino-1-cyclopropanecarboxylic acid, 99% 250MG 1-Aminocyclopropane-1-carboxylic acid 98% 1-AMino-1-carboxycyclopropane NSC 98430 1-AMinocyclopropane-1-carboxylic Acid, 95+% 1-Aminocyclopropanecarboxylic acid 1-Amino-1-cyclopropanecarboxylic acid 1-Aminocyclopropane-1-carboxylic acid, >=98% 1-Aminocyclopropane-1-carboxylic acid≥ 98% (Titration) Acpc-OH ACPC Carboxycyclopropylamine 1-amino-cyclopropanecarboxylicaci alpha-aminocyclopropanecarboxylicacid H-(1)NHCPROPN-OH CARBOXYCYCLOPROPYLAMINE 1-Aminocyclopropanecarboxylic acid(ACC) 1-AMINO-1-CYCLOPROPANECARBOXYLIC ACID 1-AMINOCYCLOPROPANECARBOXYLIC ACID 1,1-ACCP 1-AMINO-1-CYCLOPROPANECARBOXYLIC ACID, 9 7% Cyclopropanecarboxylicacid,1-amino-(6CI,7CI,8CI,9CI) H-ACC-OH.HCl a-Aminocyclopropanecarboxylic acid 1-AMINOCYCLOPROPANECARBOXYLIC ACID HYDROCHLORIDE (ACC, ACPC) 1-Amino-1-cyclopropanecarboxylic acid,99% 1-Aminocyclopropane-1-carboxylic Acid - CAS 22059-21-8 - Calbiochem 1-Aminonecarboxylic acidcyclopropa 1-ACC ACID 1-AminocycL opropane-1-carboxyL 1-Aminocyclopropanecarboxylic Acid > 1-Aminocyclopropanecarboxylic acid USP/EP/BP Supply 1-Aminocyclopropanecarboxylic acid CAS 22059-21-8 1-Aminocyclopropanecarboxylic acid 22059-21-8 1-Ethyl-1H-pyrrole-2 AMinocyclopropanecarboxylic acid 1-AMinocyclopropane-1-carboxylate Cyclopropanecarboxylic acid, 1-amino- H-ACPC-OH ACC 1-AMINOCYCLOPROPANE-1-CARBOXYLIC ACID Ac3c Fish acetyl CoA carboxylase (ACC) ELISA Kit 22059-21-8 2059-21-8 C4H7N1O2 Simple 3-Membered Ring Compounds Cyclopropanes Plant growth regulators Pesticides & Metabolites Pesticides Ion Channels Ionotropic Glutamate Receptor Modulators Ligand-Gated Ion Channels Chromatography Environmental Standards