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4,7-Dichloroquinoline

4,7-Dichloroquinoline structure

CAS No.: 86-98-6

Chemical Name:: 4,7-Dichloroquinoline

Synonyms: COPPER SEBACATE;Sulfate Impurity;4,7-dichloro-quinolin;tl1473;TL 1473;4, 7-dichloroquine;7-Dichloroquinoline;Chloroquine USP RC A;4,7-DICHLOROQUINOLINE;Amobiquine Impurity 1

CBNumber:: CB6490818

Molecular Formula:: C9H5Cl2N

Molecular Weight:: 198.05

MDL Number:: MFCD00006774

MOL File:: 86-98-6.mol

MSDS File:: SDS

Last updated:2023-09-08 13:28:03

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4,7-Dichloroquinoline Properties

Melting point	81-83 °C (lit.)
Boiling point	298.4 °F (148°C)
Density	1.4178 (rough estimate)
vapor pressure	0.103Pa at 25℃
refractive index	1.6300 (estimate)
Flash point	164 °C
storage temp.	2-30°C
solubility	chloroform: soluble50mg/mL, clear, colorless to greenish-yellow
form	Powder
pka	1.99±0.27(Predicted)
color	White to pale brown
Water Solubility	insoluble
BRN	125359
InChIKey	HXEWMTXDBOQQKO-UHFFFAOYSA-N
LogP	3.193 at 25℃
CAS DataBase Reference	86-98-6(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	Z61O2HEQ2J
NIST Chemistry Reference	Quinoline, 4,7-dichloro-(86-98-6)
EPA Substance Registry System	4,7-Dichloroquinoline (86-98-6)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS07,GHS09

Signal word

Warning

Hazard statements

H315-H317-H319-H411

Precautionary statements

P261-P264-P273-P280-P302+P352-P305+P351+P338

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36-22

WGK Germany

RTECS

VB4200000

Hazard Note

Irritant

TSCA

Yes

HS Code

29334910

NFPA 704

	1
2		0

4,7-Dichloroquinoline price More Price(35)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	PHR2438	Chloroquine Related Compound A Pharmaceutical Secondary Standard; Certified Reference Material	86-98-6	50MG	$668	2024-03-01	Buy
Sigma-Aldrich	141437	4,7-Dichloroquinoline ≥99%	86-98-6	25g	$117	2024-03-01	Buy
Sigma-Aldrich	1118328	Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard	86-98-6	15MG	$1210	2024-03-01	Buy
Sigma-Aldrich	1118328	Chloroquine Related Compound A United States Pharmacopeia (USP) Reference Standard	86-98-6	25mg	$1220	2022-05-15	Buy
TCI Chemical	D1100	4,7-Dichloroquinoline >98.0%(GC)	86-98-6	25g	$42	2024-03-01	Buy

Product number	Packaging	Price	Buy
PHR2438	50MG	$668	Buy
141437	25g	$117	Buy
1118328	15MG	$1210	Buy
1118328	25mg	$1220	Buy
D1100	25g	$42	Buy

4,7-Dichloroquinoline Chemical Properties,Uses,Production

Chemical Properties

white to light yellow crystal powder

Uses

4,7-Dichloroquinoline is used as a drug chloroquine phosphate intermediate. It was used in the synthesis of piperaquine. and as starting reagent in the synthesis of {3-amino-5-[(7-chloro-4-quinolyl)amino]phenyl}methanol.

Uses

4,7-Dichloroquinoline is used in the synthesis of hybrid aminoquinoline-triazine derivatives that show anti-microbial activity. In addition, it is used in the synthesis of novel oxazolidinones as anti -microbial agents showing efficacy against common bacterial strains. Chloroquinoline impurity.

General Description

Chloroquine Related Compound A is an impurity of chloroquine, which is a 9-aminoquinoline drug that effectively inhibits viral infections in humans.

Flammability and Explosibility

Not classified

Synthesis

4,7-Dichloroquinoline is obtained by chlorination of 7-chloro-4-hydroxyquinoline.

Purification Methods

Crystallise the dichloroquinoline from MeOH or 95% EtOH. [Beilstein 20/7 V 316.]

4,7-Dichloroquinoline synthesis

Synthesis of 4,7-Dichloroquinoline from 7-Chloroquinolin-4-ol

4,7-Dichloroquinoline Preparation Products And Raw materials

Raw materials

7-Chloroquinolin-4-ol

Preparation Products

7-Chloro-4-piperazinoquinoline 4-BROMO-7-CHLOROQUINOLINE Hydroxychloroquine CHLOROQUINE 7-chloroquinoline-4-carboxylic acid

4-Methoxyquinoline DESETHYL HYDROXY CHLOROQUINE N-(7-Chloro-4-quinolinyl)-N'-[2-[(7-chloro-4-quinolinyl)aMino]ethyl]-1,2-ethanediaMine Quinoline, 3,4,7-trichloro- 4-Chloro-5,6,7,8-tetrahydroquinoline

4,7,8-TRICHLOROQUINOLINE Amodiaquine

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4,7-Dichloroquinoline Suppliers

Global( 533)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Dideu Industries Group Limited	+86-29-89586680 +86-15129568250	1026@dideu.com	China	29474	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12453	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Anhui Ruihan Technology Co., Ltd	+8617756083858	daisy@anhuiruihan.com	China	994	58
Henan Tianfu Chemical Co.,Ltd.	+86-0371-55170693 +86-19937530512	info@tianfuchem.com	China	21695	55
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9352	55
Fluoropharm Co., Ltd.	+86-0571-85586753; +8613336034509	sales@fluoropharm.com	China	1290	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
Zhejiang ZETian Fine Chemicals Co. LTD	18957127338	stella@zetchem.com	China	2141	58

Supplier	Advantage
Capot Chemical Co.,Ltd.	60
Dideu Industries Group Limited	58
Hebei Mojin Biotechnology Co., Ltd	58
Henan Bao Enluo International TradeCo.，LTD	58
Anhui Ruihan Technology Co., Ltd	58
Henan Tianfu Chemical Co.,Ltd.	55
Hangzhou FandaChem Co.,Ltd.	55
Fluoropharm Co., Ltd.	60
career henan chemical co	58
Zhejiang ZETian Fine Chemicals Co. LTD	58

View Lastest Price from 4,7-Dichloroquinoline manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-19	4,7-Dichloroquinoline 86-98-6	US $0.00 / Kg/Drum	1g	99%	20mt	Jinan Finer Chemical Co., Ltd
2023-09-08	4,7-Dichloroquinoline 86-98-6	US $30.00 / kg	1kg	99%	1000t/year	Anhui Ruihan Technology Co., Ltd
2023-08-23	4,7-Dichloroquinoline 86-98-6	US $100.00 / KG	1KG	99%	5000KG	Hebei Mojin Biotechnology Co., Ltd

4,7-Dichloroquinoline
86-98-6
US $0.00 / Kg/Drum
99%
Jinan Finer Chemical Co., Ltd

4,7-Dichloroquinoline
86-98-6
US $30.00 / kg
99%
Anhui Ruihan Technology Co., Ltd

4,7-Dichloroquinoline
86-98-6
US $100.00 / KG
99%
Hebei Mojin Biotechnology Co., Ltd

4,7-Dichloroquinoline Spectrum

4,7-Dichloroquinoline(86-98-6)MS 4,7-Dichloroquinoline(86-98-6)¹HNMR 4,7-Dichloroquinoline(86-98-6)¹³CNMR 4,7-Dichloroquinoline(86-98-6)IR1 4,7-Dichloroquinoline(86-98-6)IR2 4,7-Dichloroquinoline(86-98-6)Raman

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4,7-DICHLOROQUINOLINE TL 1473 tl1473 4,7-Dichloroquinoline,97% 4,7-DICHLOLROQUINOLINE 4,7-DICHLOROQUINOLINE CHLOROQUINE PHOSPHATE 7-Dichloroquinoline Chloroquine Related Compound A (25 mg) (4,7-dichloroquinoline) 4,7-Dichloroquinoline,98% 4,7-Dichloroquinoline,95%,tech. Quinoline, 4,7-dichloro- 4,7-Dichloro-1-azanaphthalene Chloroquine Related CoMpound A 4,7-DICHLOROQUINOLINE, 99+% Hydroxychloroquine Sulfate Impurity 7（Hydroxychloroquine Sulfate EP Impurity G） Hydroxychloroquine Sulfate EP Impurity G Amobiquine Impurity 1 4,7-Dichloroquinoline(For Quinoline) Hydroxychloroquine sulfate Impurity 4 Amodiaquine Impurity 1 (Hydroxychloroquine Sulfate EP Impurity G) 4,7-Dichloroquinoline> Chloroquine USP RC A N4-(7-chloroquinolin-4-yl)-N1-ethylpentane-1,4-diamine sulfate 4,7-DICHLOROQUINOLINE 86-98-6 Amodiaquine Dichloro Impurity (Hydroxychloroquine EP Impurity G/ Chloroquine?Related Compound A) Chloroquine?Related Compound A (Amodiaquine Dichloro Impurity/ Hydroxychloroquine EP Impurity G) Hydroxychloroquine EP Impurity G (Amodiaquine Dichloro Impurity) High quailty 4,7-Dichloroquinoline 86-98-6 4,7- DichloroquinolineQ: What is 4,7- Dichloroquinoline Q: What is the CAS Number of 4,7- Dichloroquinoline Q: What is the storage condition of 4,7- Dichloroquinoline Chloroquine Related Compound A (4,7-dichloroquinoline) (1118328) 4,7-dichloro-quinolin Sulfate Impurity COPPER SEBACATE 4, 7-dichloroquine Chloroquine USP Related Compound A Lead hydroxide oxide sulfate 11083-39-9 4,7-dichloroquinoline (4,7-DCQ) 4,7-Dichloroquinolone Hydroxychloroquine EP Impurity G 4,7-Dichlrorquinoline 86-98-6 7640-85-7 C9H5Cl2N Halogenated Heterocycles Heterocyclic Building Blocks Haloquinolines Quinolines Building Blocks Building Blocks C8 to C10 Chemical Synthesis Halogenated Heterocycles Heterocyclic Building Blocks Haloquinolines Building Blocks Halogenated Heterocycles Heterocyclic Building Blocks QuinolinesHeterocyclic Building Blocks Quinolines, Quinazolines and derivatives