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SULFISOXAZOLE ACETYL (200 MG)

CAS No.
80-74-0
Chemical Name:
SULFISOXAZOLE ACETYL (200 MG)
Synonyms
ASIZ;Lipo Gantrisin;acetylsulfafurazole;Gantrisin Pediatric;Sulfisoxazole Acetyl;Acetyl sulfisoxazole;N1-Acetylsulfisoxazole;SULFISOXAZOLE ACETYL (200 MG);Sulfisoxazole Acetyl (1639003);1-(oxazol-2-ylsulfinyl)ethanone
CBNumber:
CB6500542
Molecular Formula:
C13H15N3O4S
Molecular Weight:
309.3409
MDL Number:
MFCD00072139
MOL File:
80-74-0.mol
MSDS File:
SDS
Last updated:2023-05-04 17:34:42

SULFISOXAZOLE ACETYL (200 MG) Properties

Melting point 193-194°
Boiling point 538.1±60.0 °C(Predicted)
Density 1.3541 (rough estimate)
refractive index 1.6320 (estimate)
pka -0.17±0.10(Predicted)
Water Solubility 80mg/L(37 ºC)
FDA UNII WBT5QH3KED

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302-H315-H319-H335
Precautionary statements  P261-P264-P270-P271-P280-P301+P312+P330-P302+P352-P304+P340+P312-P305+P351+P338-P332+P313-P337+P313-P362-P403+P233-P405-P501
HS Code  2935904000

SULFISOXAZOLE ACETYL (200 MG) price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 1639003 N-[(4-Aminophenyl)sulfonyl]-N-(3,4-dimethyl-5-isoxazolyl)acetamide 80-74-0 200mg $280 2024-03-01 Buy
TRC S689225 SulfisoxazoleAcetyl 80-74-0 100mg $130 2021-12-16 Buy
TRC S689225 SulfisoxazoleAcetyl 80-74-0 200mg $200 2021-12-16 Buy
Medical Isotopes, Inc. 61837 SulfisoxazoleAcetyl 80-74-0 100mg $625 2021-12-16 Buy
Medical Isotopes, Inc. 61837 SulfisoxazoleAcetyl 80-74-0 1g $1275 2021-12-16 Buy
Product number Packaging Price Buy
1639003 200mg $280 Buy
S689225 100mg $130 Buy
S689225 200mg $200 Buy
61837 100mg $625 Buy
61837 1g $1275 Buy

SULFISOXAZOLE ACETYL (200 MG) Chemical Properties,Uses,Production

Originator

Gantrisin Acetyl ,Roche ,US ,1954

Uses

Sulfisoxazole Acetyl is an antibiotic used in the prevention of infection especially when used in conjunction with erythromycin.

Uses

Antibacterial.

Definition

ChEBI: Sulfisoxazole acetyl is a sulfonamide and a member of benzenes.

Manufacturing Process

267 grams (1 mol) of sulfisoxazole were suspended in 400 ml of acetone and 79 grams (1 mol) of dry pyridine at 20-25°C in a round-bottom flask equipped with a stirrer and thermometer. 132 grams (1 mol) of acetic anhydride were added within 3 minutes with stirring. The sulfisoxazole dissolved in the mixture and a clear solution resulted. The temperature rose to 39-40°C. After stirring for several minutes, the product started to crystallize as a white crystalline mush. The temperature rose to 42-43°C maintained itself at this temperature for 15-30 minutes, and then started to drop. Stirring was continued for 5 hours and the mixture was then allowed to stand for 10 hours. One liter of 2.5-3.0% ice-cold aqueous ammonia and some fresh ice were then added while stirring and the crystals were filtered without delay. The crystals were washed on the filter with 1 liter of ice-cold 1% ammonia and then with 1 liter of water. The material on the filter was well pressed off, washed with 200-300 ml of alcohol and dried at 70°C to constant weight. The N-monoacetyl sulfisoxazole melted at 193-194°C and showed a positive Bratton-Marshall reaction and a positive Hucknall-Turfat reaction.
The product is in the form of colorless crystals which are somewhat water repellent. It is insoluble in alkali but is saponified upon standing in alkaline suspension (3% ammonia). It is soluble in strong acids (20-36% HCl or 10 N H2SO4) and is rapidly saponified upon standing.

brand name

Gantrisin (Roche).

Therapeutic Function

Antimicrobial

General Description

Sulfisoxazole acetyl shares the actions and usesof the parent compound, sulfisoxazole. The acetyl derivativeis tasteless and, therefore, suitable for oral administration, especiallyin liquid preparations. The acetyl compound is splitin the intestinal tract and absorbed as sulfisoxazole; that is, itis a prodrug for sulfisoxazole.

SULFISOXAZOLE ACETYL (200 MG) Preparation Products And Raw materials

Global( 39)Suppliers
Supplier Tel Email Country ProdList Advantage
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 7836 58
Shaanxi Dideu Medichem Co. Ltd
+86-029-81148696 +8615536356810 1047@dideu.com China 3984 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Dideu Industries Group Limited
+86-29-89586680 +86-15129568250 1026@dideu.com China 29831 58
Dayang Chem (Hangzhou) Co.,Ltd.
571-88938639 +8617705817739 info@dycnchem.com CHINA 52867 58
Hebei Duling International Trade Co. LTD
+8618032673083 sales05@hbduling.cn China 15755 58
Protheragen-ING
+16313385890 info@protheragen-ing.com United States 528 58
Jilin Chinese Academy of Sciences-yanshen Technology
+undefined18143011203 info@chemextension.com China 42057 58
Amadis Chemical Company Limited
571-89925085 sales@amadischem.com China 132020 58

View Lastest Price from SULFISOXAZOLE ACETYL (200 MG) manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
SULFISOXAZOLE ACETYL (200 MG) USP/EP/BP pictures 2021-07-16 SULFISOXAZOLE ACETYL (200 MG) USP/EP/BP
80-74-0
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
 Sulfisoxazole Acetyl       pictures 2020-06-19 Sulfisoxazole Acetyl
80-74-0
US $628.00 / KG 1KG 98.0% 4T Shaanxi Dideu Medichem Co. Ltd
SULFISOXAZOLE ACETYL (200 MG) Acetamide, N-[(4-aminophenyl)sulfonyl]-N-(3,4-dimethyl-5-isoxazolyl)- Acetyl sulfisoxazole Lipo Gantrisin N-(3,4-Dimethyl-5-isoxazolyl)-N-sulfanilylacetamide n-3,4-dimethylisoxazol-5-yl-n-sulfanilylacetamide N-Acetyl-4-amino-N-(3,4-dimethyl-5-isoxazolyl)benzenesulfonamide Sulfisoxazole Acetyl N-3,4-dimethylisoxazol-5-yl-N-sulphanilylacetamide acetylsulfafurazole 5-[N-Acetyl-N-(p-aminophenylsulfonyl)amino]-3,4-dimethylisoxazole N-(4-Aminophenylsulfonyl)-N-(3,4-dimethyl-5-isoxazolyl)acetamide N-(4-aminophenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)acetamide N-(4-aminophenyl)sulfonyl-N-(3,4-dimethylisoxazol-5-yl)acetamide N-(4-azanylphenyl)sulfonyl-N-(3,4-dimethyl-1,2-oxazol-5-yl)ethanamide 1-(oxazol-2-ylsulfinyl)ethanone N1-Acetylsulfisoxazole ASIZ SULFISOXAZOLE ACETYL (200 MG) USP/EP/BP Sulfisoxazole Acetyl (1639003) Gantrisin Pediatric Inhibitor,antibacterial action,N1-Acetylsulfisoxazole,inhibit,Bacterial,Sulfisoxazole acetyl,Sulfisoxazole derivative,orally active,dihydropteroate synthase 80-74-0