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Phenylephrine hydrochloride

Phenylephrine hydrochloride
Phenylephrine hydrochloride
Chemical Name:
Phenylephrine hydrochloride
Molecular Formula:
Formula Weight:
MOL File:

Phenylephrine hydrochloride Properties

Melting point:
143-145 °C(lit.)
-47 º (c=2, H2O)
refractive index 
-45.5 ° (C=1, H2O)
Flash point:
storage temp. 
Desiccate at RT
Crystalline Powder
pK1 8.77; pK2 9.84(at 25℃)
White to almost white
Water Solubility 
>=10 g/100 mL at 21 ºC
CAS DataBase Reference
61-76-7(CAS DataBase Reference)
EPA Substance Registry System
Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino) methyl]-, hydrochloride, (.alpha.R)-(61-76-7)
  • Risk and Safety Statements
  • Hazard and Precautionary Statements (GHS)
Hazard Codes  Xn,T,F
Risk Statements  22-36/37/38-39/23/24/25-23/24/25-11
Safety Statements  26-36-37/39-45-36/37-16-7
RIDADR  3249
WGK Germany  3
RTECS  DO7525000
HazardClass  6.1(b)
PackingGroup  III
Signal word: Danger
Hazard statements:
Code Hazard statements Hazard class Category Signal word Pictogram P-Codes
H225 Highly Flammable liquid and vapour Flammable liquids Category 2 Danger P210,P233, P240, P241, P242, P243,P280, P303+ P361+P353, P370+P378,P403+P235, P501
H302 Harmful if swallowed Acute toxicity,oral Category 4 Warning P264, P270, P301+P312, P330, P501
H315 Causes skin irritation Skin corrosion/irritation Category 2 Warning P264, P280, P302+P352, P321,P332+P313, P362
H319 Causes serious eye irritation Serious eye damage/eye irritation Category 2A Warning P264, P280, P305+P351+P338,P337+P313P
H335 May cause respiratory irritation Specific target organ toxicity, single exposure;Respiratory tract irritation Category 3 Warning
H370 Causes damage to organs Specific target organ toxicity, single exposure Category 1 Danger P260, P264, P270, P307+P311, P321,P405, P501
Precautionary statements:
P210 Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P260 Do not breathe dust/fume/gas/mist/vapours/spray.
P261 Avoid breathing dust/fume/gas/mist/vapours/spray.
P280 Wear protective gloves/protective clothing/eye protection/face protection.
P311 Call a POISON CENTER or doctor/physician.
P301+P310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.
P305+P351+P338 IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Phenylephrine hydrochloride price More Price(17)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich P-078 R(-)-Phenylephrine hydrochloride solution 61-76-7 078-1ml $69 2017-11-08 Buy
Sigma-Aldrich 1533002 Phenylephrine hydrochloride United States Pharmacopeia (USP) Reference Standard 61-76-7 200mg $355 2017-11-08 Buy
TCI Chemical P0398 (R)-Phenylephrine Hydrochloride >98.0%(HPLC)(T) 61-76-7 5g $39 2017-12-01 Buy
TCI Chemical P0398 (R)-Phenylephrine Hydrochloride >98.0%(HPLC)(T) 61-76-7 25g $119 2017-12-01 Buy
Cayman Chemical 18619 R-(-)-Phenylephrine (hydrochloride) ≥98% 61-76-7 50mg $25 2017-11-08 Buy

Phenylephrine hydrochloride Chemical Properties,Uses,Production

Chemical Properties

white to almost white crystalline powder


α-Adrenergic agonist. Mydriatic; decongestant.




ChEBI: A hydrochloride that is the monohydrochloride salt of phenylephrine.

General Description

Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.

Air & Water Reactions

May be sensitive to prolonged exposure to air and light. Water soluble.

Reactivity Profile

Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.

Fire Hazard

Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.

Biological Activity

α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.

Phenylephrine hydrochloride Preparation Products And Raw materials

Raw materials

Preparation Products

Phenylephrine hydrochloride Suppliers

Global( 225)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Capot Chemical Co.,Ltd.
+86 (0)571-855 867 18
+86 (0)571-858 647 95 China 19953 60
Henan DaKen Chemical CO.,LTD.
+86-371-55541817 CHINA 2914 58
Henan Tianfu Chemical Co.,Ltd.
0371-55170693 CHINA 20810 55
Mainchem Co., Ltd.
0592-6210733 CHINA 3168 55
Jinan Yuantai Pharmaceutical Co.,Ltd 0531-69959492 18560053868
0531-88603458 China 264 58
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933; China 96820 76
Meryer (Shanghai) Chemical Technology Co., Ltd. +86-(0)21-61259100(Shanghai) +86-(0)755-86170099(ShenZhen) +86-(0)10-62670440(Beijing)
+86-(0)21-61259102(Shanghai) +86-(0)755-86170066(ShenZhen) +86-(0)10-88580358(Beijing) China 40398 62
INTATRADE GmbH +49 3493/605464
+49 3493/605470 Germany 3588 66
3B Pharmachem (Wuhan) International Co.,Ltd. 86-21-50328103 * 801、802、803、804 Mobile:18930552037
86-21-50328109 China 15940 69
TCI (Shanghai) Development Co., Ltd. 800-988-0390
021-67121385 China 22830 81

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