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Phenylephrine hydrochloride

CAS No.61-76-7
Chemical Name:Phenylephrine hydrochloride
Synonyms:uri;fenox;emagrin;efricel;lexatol;rhinall;synasal;almefrin;consdrin;fenilfar
CBNumber:CB6762113
Molecular Formula:C9H14ClNO2
Formula Weight:203.67
MOL File:61-76-7.mol
Phenylephrine hydrochloride Property
mp : 143-145 °C(lit.)
alpha : -47 º (c=2, H2O)
refractive index : -45.5 ° (C=1, H2O)
storage temp. : Desiccate at RT
Water Solubility : >=10 g/100 mL at 21 ºC
Merck : 7286
CAS DataBase Reference: 61-76-7(CAS DataBase Reference)
EPA Substance Registry System: Benzenemethanol, 3-hydroxy-.alpha.-[(methylamino) methyl]-, hydrochloride, (.alpha.R)-(61-76-7)
Safety
Hazard Codes : Xn
Risk Statements : 22-36/37/38
Safety Statements : 26-36-37/39
RIDADR : 3249
WGK Germany : 3
RTECS : DO7525000
HazardClass : 6.1(b)
PackingGroup : III

Phenylephrine hydrochloride Chemical Properties,Usage,Production

Chemical Properties
white to almost white crystalline powder
Usage
α-Adrenergic agonist. Mydriatic; decongestant.
General Description
Odorless white microcrystalline powder. Bitter taste. pH (1% aqueous solution) about 5.
Air & Water Reactions
May be sensitive to prolonged exposure to air and light. Water soluble.
Reactivity Profile
Phenylephrine hydrochloride is incompatible with acids, acid chlorides, acid anhydrides and oxidizing agents. Phenylephrine hydrochloride is also incompatible with butacaine, alkalis and ferric salts.
Fire Hazard
Flash point data for Phenylephrine hydrochloride are not available; however, Phenylephrine hydrochloride is probably combustible.
Biological Activity
α 1 -adrenoceptor agonist; pK i values are 5.86, 4.87 and 4.70 for α 1D , α 1B and α 1A receptors respectively.
Phenylephrine hydrochloride Preparation Products And Raw materials
Raw materials
Benzyl alcohol Toluene Diethyl ether
Preparation Products
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61-76-7(Phenylephrine hydrochloride)Related Search:
PHOMOPSIN A (R)-A,A-BIS(3-METHOXYPHENYL)-2-PYRROLIDINEMETHANOL HYDROCHLORIDE (1R,2S)-(-)META-HYDROXYEPHEDRINE HYDROCHLORIDE Naxagolide N-[(1R,2R)-1,2,3,4-TETRAHYDRO-1-HYDROXY-7-METHOXY-2-NAPHTHALENYL]-CHLOROACETAMIDE (-)-2-[METHYLAMINO]-1-PHENYLPROPANE Chenodeoxycholic acid Phenylephrine DL-PHENYLEPHRINE HYDROCHLORIDE CHLOROPHOSPHONAZO III Phenylephrine hydrochloride Benzyl alcohol L(-)-Epinephrine Benzyl Ethyl acetate Topotecan hydrochloride Ursodeoxycholic acid Isoprenaline hydrochloride
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