Ensitrelvir
- CAS No.
- 1471484-62-4
- Chemical Name:
- Ensitrelvir
- Synonyms
- (E)-1-(2,4,5-trifluorobenzyl)-6-(6-chloro-2-methyl-2H-indazol-5-ylimino)-3-((1-methyl-1H-1,2,4-triazol-3-yl)methyl)-1,3,5-triazinane-2,4-dione;1H-Indole-2-carboxamide, N-[(1S)-1-[[[(1S)-2-(2-benzothiazolyl)-2-oxo-1-[[(3S)-2-oxo-3-pyrrolidinyl]methyl]ethyl]amino]carbonyl]-3-methylbutyl]-4-methoxy-;YH53;S-217622;N-((S)-1-(((S)-1-(benzo[d]thiazol-2-yl)-1-oxo-3-((S)-2-oxopyrrolidin-3-yl)propan-2-yl)amino)-4-methyl-1-oxopentan-2-yl)-4-methoxy-1H-indole-2-carboxamide
- CBNumber:
- CB69306536
- Molecular Formula:
- C30H33N5O5S
- Molecular Weight:
- 575.68
- MDL Number:
- MFCD34567722
- MOL File:
- 1471484-62-4.mol
Ensitrelvir Chemical Properties,Uses,Production
Uses
S-217622 is indicated for the treatment of COVID-19.
Synthesis
The synthesis of S-217622 is as follows:
To a solution of 18 (0.200g, 0.5mmol) in CH2Cl2 (3mL) at 0°C was added TFA/ H2O (10:1, 2mL), and the solution was stirred for 1h. After evaporating the solvent under reduced pressure, the corresponding deprotected lactam residue (0.100g, 0.53mmol) was coupled to the carboxylic acid 14a (0.136g, 0.38mmol) using the coupling agent HBTU (0.147g, 0.38mmol) in the presence of diisopropylethylamine (0.050mL, 0.38mmol) in DMF (3mL) at 0°C. After 5min stirring, the ice bath was removed, and the solution was allowed to stir for 2h under ambient conditions. The solvent was then evaporated under high vacuum, and the residue was dissolved in ethyl acetate (50mL). The organic layer was washed with 5% citric acid (20mL×2), 5% NaHCO3 (20mL×2), and brine (25mL). The solution was dried over Na2SO4, filtered, and evaporated under reduced pressure to give S-217622.
Ensitrelvir Preparation Products And Raw materials
Raw materials
Preparation Products
Ensitrelvir Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Jinan Jianfeng Chemical Co., Ltd | 0531-88110457; +8615562555968 | info@pharmachemm.com | China | 222 | 58 |
| Nantong Guangyuan Chemicl Co,Ltd | +undefined17712220823 | admin@guyunchem.com | China | 616 | 58 |
| Univar Solutions(China) Co., Ltd. | +8615902132654 | ivy.zhuang@univarsolutions.com | China | 654 | 58 |
| Senova Technology Co. Ltd. | +86-0755-86703119 +8618503098836 | info@senovatech.com | China | 350 | 58 |
| Hebei Duling International Trade Co. LTD | +8618032673083 | sales05@hbduling.cn | China | 15743 | 58 |
| Nantong HI-FUTURE Biology Co., Ltd. | +undefined18051384581 | sales@chemhifuture.com | China | 3136 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| Wuhan Topule Biopharmaceutical Co., Ltd | +8618327326525 | masar@topule.com | China | 8474 | 58 |
| Wuhan Biocar Pharmacy Co.，Ltd | 13343447621 | linkdevil@foxmail.com | China | 62 | 58 |
| Wuhan Biocar Pharmacy Co.，Ltd | 18665676617 | 2956176220@qq.com | China | 61 | 58 |
View Lastest Price from Ensitrelvir manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-05-09 | Ensitrelvir
1471484-62-4
|
US $20.00 / kg | 1kg | 99% purity | 20t | Jinan Jianfeng Chemical Co., Ltd | |
 |
2024-03-08 | YH-53
1471484-62-4
|
US $10.00 / kg | 1kg | 99% | 1000kg | Nantong Guangyuan Chemicl Co,Ltd | |
 |
2022-03-11 | Ensitrelvir
1471484-62-4
|
US $0.00 / kg | 1kg | 99% | 100kg | Senova Technology Co. Ltd. |
-
- Ensitrelvir
1471484-62-4
- US $20.00 / kg
- 99% purity
- Jinan Jianfeng Chemical Co., Ltd
-
- YH-53
1471484-62-4
- US $10.00 / kg
- 99%
- Nantong Guangyuan Chemicl Co,Ltd
-
- Ensitrelvir
1471484-62-4
- US $0.00 / kg
- 99%
- Senova Technology Co. Ltd.