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Rosiglitazone

Description References
Rosiglitazone
Rosiglitazone
CAS No.
122320-73-4
Chemical Name:
Rosiglitazone
Synonyms
AVANDIA;BRL 49653;ROSIGLIAZONE;roiglitazone;ROSIGLITAZONE;ROSIGLITAZONEHCL;ROSIGLITAZONE 99%;ROSIGLITAZONE HCL;ROEIGLITAZONEMALEATE;Rosiglitazone, >=98.5%
CBNumber:
CB7133275
Molecular Formula:
C18H19N3O3S
Formula Weight:
357.43
MOL File:
122320-73-4.mol

Rosiglitazone Properties

Melting point:
153-155 C
storage temp. 
2-8°C
solubility 
DMSO: ≥10mg/mL
Merck 
14,8265
CAS DataBase Reference
122320-73-4(CAS DataBase Reference)

SAFETY

Hazard Codes  Xi
Risk Statements  36/38
Safety Statements  26-37/39
RTECS  XJ5813850
Hazardous Substances Data 122320-73-4(Hazardous Substances Data)

Rosiglitazone price More Price(8)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich R2408 Rosiglitazone ≥98% (HPLC) 122320-73-4 10mg $69.8 2017-11-08 Buy
Sigma-Aldrich R2408 Rosiglitazone ≥98% (HPLC) 122320-73-4 50mg $283 2017-11-08 Buy
TCI Chemical R0106 Rosiglitazone >98.0%(HPLC)(T) 122320-73-4 200mg $60 2017-12-01 Buy
TCI Chemical R0106 Rosiglitazone >98.0%(HPLC)(T) 122320-73-4 1g $212 2017-12-01 Buy
Cayman Chemical 71740 Rosiglitazone ≥98% 122320-73-4 10mg $28 2017-11-08 Buy

Rosiglitazone Chemical Properties,Uses,Production

Description

Rosiglitazone is a type of thiazolidinedione antidiabetics. Thiazolidinedione are agonists for peroxisome-proliferator–activated receptor γ (PPAR-γ). PPAR-γ receptors are ligand-activated nuclear transcription factors that modulate gene expression, lowering blood glucose primarily by increasing insulin sensitivity in peripheral tissues.
Rosiglitazone is widely used to lower blood glucose levels in patients with type 2 diabetes mellitus. Rosiglitazone functionalizes by makes the cells of the body more sensitive to the naturally produced insulin in body. It shouldn’t be used if the patient is injecting or inhaling insulin. Using rosiglitazone with insulin could increase the risk of heart failure. Patients having heart failure with symptoms or moderate to severe heart failure should not use Rosiglitazone.

References

[1] http://www.nejm.org/doi/full/10.1056/NEJMoa072761#t=article
[2] http://circ.ahajournals.org/content/128/8/785
[3] https://www.drugs.com/cdi/rosiglitazone.html

Uses

antidiabetic

Uses

A potent and selective PPARγ agonist.

Rosiglitazone Preparation Products And Raw materials

Raw materials

Preparation Products


Rosiglitazone Suppliers

Global( 220)Suppliers
Supplier Tel Fax Email Country ProdList Advantage
Shenzhen Sendi Biotechnology Co.Ltd.
0755-23311925 18102838259
0755-23311925 Abel@chembj.com CHINA 3228 55
Mainchem Co., Ltd.
+86-0592-6210733
+86-0592-6210733 sales@mainchem.com CHINA 32766 55
Lianyungang happen teng technology co., LTD
15950718863
wang666xt@163.com CHINA 304 58
Shanghai JONLN Reagent Co., Ltd. 400-0066-400;021-60496031
021-55660885 shjlsw@163.com China 10295 55
J & K SCIENTIFIC LTD. 400-666-7788 +86-10-82848833
+86-10-82849933 jkinfo@jkchemical.com;market6@jkchemical.com China 96816 76
Chembest Research Laboratories Limited +86(0)21-20908456
+86(0)21-58180499 sales@biochembest.com; market@biochembest.com China 6082 61
TCI (Shanghai) Development Co., Ltd. 800-988-0390
021-67121385 sales@tcishanghai.com.cn China 22909 81
ShangHai DEMO Chemical Co.,Ltd 400-021-7337 qq:2355568890
0086-21-50182339 sales@demochem.com; export1@demochem.com China 2608 57
Beijing dtftchem Technology Co., Ltd. 13651141086; 86(10)60275028、60275820
86 (10) 60270825 dtftchem@sina.com China 3434 62
BePharm Ltd 4001-647-117; 021-61629020
021-61629029 product@bidepharmatech.com China 24692 61

122320-73-4(Rosiglitazone)Related Search:


  • 5-(4-[2-(METHYL-PYRIDIN-2-YL-AMINO)-ETHOXY]-BENZYL)-THIAZOLIDINE-2,4-DIONE
  • 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione
  • 122320-73-4
  • AVANDIA
  • ROSIGLITAZONE
  • ROSIGLITAZONE HCL
  • Rosiglitazone free base
  • Rosiglitazone and its intermediates
  • ROSIGLITAZONE 99%
  • RosiglitazoneBase/Hcl/Maleate
  • C18H19N3O3S
  • 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzylidine]-2,4-thiazolidinedione
  • 15141-29-0
  • 122320-70-4
  • 5-[[4-[2-(methyl-pyridin-2-yl-amino)ethoxy]phenyl]methyl]thiazolidine-2,4-dione
  • BRL 49653
  • Active Pharmaceutical Ingredients
  • ROEIGLITAZONEMALEATE
  • ROSIGLITAZONEHCL
  • Rosiglitazone
  • API's
  • ROSIGLIAZONE
  • ROSIGLIAZONE (5-{4-[2-(N-methyl-N-2-pyridyl)amino]-ethoxy}benzyl}-2,4-thiazolidinedione)
  • 5-[[4-[2-[methyl(pyridin-2-yl)amino]ethoxy]phenyl]methyl]-1,3-thiazolidine-2,4-dione
  • 5-[4-[2-[methyl(2-pyridyl)amino]ethoxy]benzyl]thiazolidine-2,4-quinone
  • 2,4-Thiazolidinedione, 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-
  • (RS)-5-[4-(2-[Methyl(pyridin-2-yl)aMino]ethoxy)benzyl]thiazolidine-2,4-dione
  • 2-[(2-benzoylphenyl)aMino]-3-{4-[2-(5-Methyl-2-phenyl-1,3-oxazol-4-yl)ethoxy]phenyl}propanoic acid
  • Rosiglitazone (Avandia)
  • Rosiglitazone(BRL 49653)
  • roiglitazone
  • Inhibitor
  • AVANDIA
  • 5-[[4-[2-(methyl-2-pyridinylamino)ethoxy]phenyl]methyl]-2,4-tiazolidinedione
  • Rosiglitazone 5-[[4-[2-(Methyl-2-pyridinylamino)ethoxy]-phenyl]methyl]-2,4-thiazolidine-dione
  • Rosiglitazone, >=98.5%
  • 5-[4-[2-(N-Methyl-N-(2-pyridyl)amino)ethoxy]benzyl]thiazolidine-2,4-dione
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