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Potassium Citrate

CAS No.
866-84-2
Chemical Name:
Potassium Citrate
Synonyms
Tripotassium citrate;SODIUM POTASSIUM;Potassium acid citrate;sdTripotassium Citrate;HYDROXY CITRIC ACID SYNTHETIC;tripotassiuM citrate anhydrous;POTASSIUM CITRATE TRIBASIC SOLUTION;kajos;porekal;seltz-k
CBNumber:
CB7134348
Molecular Formula:
C6H9KO7
Molecular Weight:
232.23
MDL Number:
MFCD00036362
MOL File:
866-84-2.mol
MSDS File:
SDS
Last updated:2024-03-06 18:00:57

Potassium Citrate Properties

Melting point decomposes at 230℃ [KIR78]
Density 1.187
solubility H2O: 1 M at 20 °C, clear, colorless
PH 8.59(1 mM solution);8.9(10 mM solution);9.01(100 mM solution);7.47(1000 mM solution)
Odor at 100.00?%. odorless
Water Solubility 60.91 g/100g saturated solution in water (25°C) [MER06]
λmax λ: 260 nm Amax: 0.045
λ: 280 nm Amax: 0.025
InChI InChI=1S/C6H8O7.K.H/c7-3(8)1-6(13,5(11)12)2-4(9)10;;/h13H,1-2H2,(H,7,8)(H,9,10)(H,11,12);;
InChIKey JOSYFFAWJFRGHM-UHFFFAOYSA-N
SMILES C(O)(C(=O)O)(CC(=O)O)CC(=O)O.[KH]
LogP -0.280 (est)
CAS DataBase Reference 866-84-2(CAS DataBase Reference)
FDA 21 CFR 184.1625; 582.1625; 582.6625; 310.545
Indirect Additives used in Food Contact Substances TRIPOTASSIUM CITRATE
EWG's Food Scores 1
FDA UNII 86R1NVR0HW
ATC code A12BA02
EPA Substance Registry System 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, tripotassium salt (866-84-2)

SAFETY

Risk and Safety Statements

WGK Germany  1

Potassium Citrate price More Price(3)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 89306 Potassium citrate tribasic solution BioUltra, 1?M in H2O 866-84-2 100ML $64.1 2023-06-20 Buy
Sigma-Aldrich 89306 Potassium citrate tribasic solution BioUltra, 1?M in H2O 866-84-2 500ML $258 2023-06-20 Buy
Usbiological 286424 Potassium citrate 866-84-2 100g $370 2021-12-16 Buy
Product number Packaging Price Buy
89306 100ML $64.1 Buy
89306 500ML $258 Buy
286424 100g $370 Buy

Potassium Citrate Chemical Properties,Uses,Production

Potassium citrate

The applications of potassium citrate (or tripotassium citrate) mainly derive from its alkaline properties. It is used to treat kidney stones composed of uric acid and cysteine, as well as other renal failures caused by excess acidity, including in veterinary applications. As an additive to soft drinks and other edibles, it also functions as an acid buffer, less bitter than other potassium salts, and with less sodium than trisodium citrate.
An additional use of potassium citrate is to supplement potassium in patients with hypokalemia, preventing and treating gout and arrhythmia.

Prevention of urinary calculi drug

Potassium citrate is the drug which is most commonly used to prevent calculus. It was found that in the urine pH value and citric acid value and have a very close relationship with the formation urinary tract calculus. In an acidic urine (pH <5.5), the uric acid solubility is very low, so it is likely to cause uric acid calculus; while in alkaline urine (pH> 7), it is easy to form calcium or magnesium phosphate calculus. 63% of urinary calculus patients are below normal urine citrate, and potassium citrate can provide a lot of citric acid to enhance the urine pH value. So for uric acid calculus, It has a very significant therapeutic effect to low calcium citrate calculus disease and tubular poisoning calcium calculus disease. But It will raise the concentration of potassium and lower the concentration of ammonium ion in urinary, which is because not only complements the citric acid, but also supplements of potassium. Since potassium metabolism is very quickly in the body, there is no change in blood potassium concentration. It has little effect on the body. The daily amount of total urine, oxalate, phosphate, sodium, magnesium, sulfate and uric acid and other aspects test from patients with uric acid calculus, it is found that it is not affected by taking potassium citrate.

Chemical properties

Colorless crystals or white crystalline powder, odorless, cool and salty, slight deliquescence, soluble in water and glycerin, insoluble in ethanol. Tests show that the product had no significant harm to the human body, ADI doesn’t need special provision (FAO/WHO, 1994).

Uses

As a preservative, stabilizing and pH buffering agents and others. China provides for various types of food, according to production needs to use appropriately.
Used in the food, pharmaceutical and other industries, as buffering agents, chelating agents, flavoring agents, stabilizers, antioxidants, emulsifying salts.

Production methods

Citric acid and potassium hydroxide or potassium bicarbonate derived products.
C6H8O7 + 3KHCO3 → CaH5K3O7 · H2O + 3CO2 ↑ + 2H2O

Reference

https://en.wikipedia.org/wiki/Potassium_citrate
https://kidneystones.uchicago.edu/how-citrate-gets-into-the-urine/
https://www.drugbank.ca/drugs/DB09125
http://www.urocit-k.com/
http://www.jungbunzlauer.com/en/products/special-salts/tripotassium-citrate.html
https://www.quora.com/Why-is-potassium-citrate-buffer-is-an-acid-buffer

Description

Potassium citrate is a potassium salt of citric acid with the molecular formula C6H5K3O7. It is a white, slightly hygroscopic crystalline powder. It is odorless with a saline taste.
As a food additive, potassium citrate is used to regulate acidity and is known as E number E332. Medicinally, it may be used to control kidney stones derived from either uric acid or cystine.

Chemical Properties

Colorless or white crystals or powder; cooling, saline taste; odorless; deliquescent. Soluble in water and glycerol; almost insoluble in alcohol.

Uses

For use as an electrolyte replenisher and in the treatment of hypokalemia.

Uses

Potassium citrate is rapidly absorbed when given by mouth and is excreted in the urine. Since it is an alkaline salt it is effective in reducing the pain and frequency of urination when these are caused by highly acidic urine . It is used for this purpose in dogs and cats, but is chiefly employed as a non-irritating diuretic.
Potassium citrate is an effective way to treat/manage gout and arrhythmia, if the patient is hypokalemic.
It is widely used to treat urinary calculi (kidney stones) and is often used by patients with cystinuria .

Uses

potassium citrate is it acts as a buffer, maintaining product pH constant, a pH adjuster and a product stabilizer. This is a potassium salt.

Definition

ChEBI: The anhydrous form of the tripotassium salt of citric acid.

Production Methods

Potassium citrate is produced by adding potassium bicarbonate or potassium carbonate to a solution of citric acid until effervescence ceases, filtering the solution and evaporating to granulation.

Flammability and Explosibility

Non flammable

Industrial uses

Potassium citrate is used in the United Kingdom as an over-the-counter drug for the relief from discomfort experienced in mild urinary-tract infections by increasing the urinary pH. It should be not given to men if they experience pain in the kidney area (risk of kidney stones) or if blood or pus is present in the urine. Also, patients with raised blood pressure or diabetes should avoid taking potassium citrate without consultation with their general practitioner (GP). Caution is generally advised to patients with renal impairment, cardiac problems and the elderly [3a].

Safety Profile

Poison by intravenous route. When heated to decomposition it emits toxic fumes of K2O.

Precautions

Potassium citrate is usually administered by mouth in dilute aqueous solution. This is because of its somewhat caustic effect on the stomach lining, and the potential for other mild health hazards.
In states where non-prescription potassium citrate is legal, the maximum allowable over-the-counter (OTC) dose for elemental potassium is regulated by the FDA to be no more than 100 mg (approximately 3 % of the daily allowance ) . Pure potassium citrate contains 38.28 % potassium.

Potassium Citrate Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 377)Suppliers
Supplier Tel Email Country ProdList Advantage
Zibo Wei Bin Import & Export Trade Co. Ltd.
+86-0533-2091136 +8613864437655 ziboweibinmaoyi@163.com China 100 58
Wuhan Boyuan Import & Export Co., LTD
+86-15175982296 15175982296; Mike@whby-chem.com China 983 58
Hebei Mojin Biotechnology Co., Ltd
+86-13288715578 +86-13231137666 sales@hbmojin.com China 12409 58
Hebei Dongdu Import and Export Co. LTD
+86-15333296769 +86-15333296769 manager@cndongdu.com China 71 58
Anhui Ruihan Technology Co., Ltd
+8617756083858 daisy@anhuiruihan.com China 994 58
Jiangsu Kolod Food Ingredients Co.,Ltd.
+86-518-85110578 +8618805133257 sales3257@jskolod.com China 132 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21703 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29919 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58

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View Lastest Price from Potassium Citrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Potassium Citrate pictures 2024-03-13 Potassium Citrate
866-84-2
US $100.00 / kg 1kg 99% 1t Zibo Wei Bin Import & Export Trade Co. Ltd.
Potassium citrate without water pictures 2024-03-06 Potassium citrate without water
866-84-2
US $23.00-18.00 / kg 1kg 99.9% 50000tons Wuhan Boyuan Import & Export Co., LTD
potassium citrate pictures 2023-12-20 potassium citrate
866-84-2
US $800.00 / ton 5ton 99% 10000tons/Month Hebei Dongdu Import and Export Co. LTD
  • Potassium Citrate pictures
  • Potassium Citrate
    866-84-2
  • US $100.00 / kg
  • 99%
  • Zibo Wei Bin Import & Export Trade Co. Ltd.
tripotassium 2-hydroxypropane-1,2,3-tricarboxylate 2-Hydroxy-1,2,3-propanetricarboxylic acid tripotassium salt Tripotassium-2-hydroxypropane-1,2,3-tricarboxylateanhydrous Tripotassiumcitrate:forfood,E332 1,2,3-Propanetricarboxylicacid,2-hydroxy-,tripotassiumsalt 2,3-propanetricarboxylicacid,2-hydroxy-tripotassiumsalt kajos potassiuM 2-hydroxypropane-1,2,3-tricarboxylate Potassium Citrate Anhydrous Powder kaliksir porekal potassiumcitrateanhydrous seltz-k POTASSIUM CITRATE Potassium citrate tribasic solution, 1M in water Potassium citrate without water Pharmaceutical Intermediates grade potassium citrate anhydrous CAS 866-84-2 Pharmaceutical Intermediates grade potassium citrate anhydrous 1,2,3-Propanetricarboxylic acid, 2-hydroxy-, potassium salt (1:3) Potassium Citrate anhydrous o tripotassium citrate Potassium Citrate USP/EP/BP tripotassiuM citrate anhydrous SODIUM POTASSIUM POTASSIUM CITRATE TRIBASIC SOLUTION Tripotassium citrate Potassium acid citrate sdTripotassium Citrate HYDROXY CITRIC ACID SYNTHETIC 866-84-2 112025-60-5 C6H5K3O7 K3C6H5O7H2O C6H5O73K K3C6H5O7 C6H8O73K Protein Analysis Proteomics and Protein Expression X-Ray Crystallography BioChemical Optimization Reagents Buffer SolutionsBiochemicals and Reagents ChelatorsProtein Structural Analysis AlphabeticalBiological Buffers Biological Buffers BioUltra Buffers Optimization Reagents X-Ray Crystallography Food additives 866-84-2