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6-Methoxy-2-naphthaldehyde

CAS No.
3453-33-6
Chemical Name:
6-Methoxy-2-naphthaldehyde
Synonyms
TIMTEC-BB SBB010060;Mitotane Impurity 17;LABOTEST-BB LT01147524;ASINEX-REAG BAS 07663025;6-Methoxy-2-Naphtaldehyde;6-Methoxy-2-napthaldehyde;6-METHOXY-2-NAPHTHALDEHYDE;6-Methoxy-2-Naphthaidehyde;6-methoxy-2-naphthalaldehyde;6-Methoxy-2-naphthaldehyde>
CBNumber:
CB7136100
Molecular Formula:
C12H10O2
Molecular Weight:
186.21
MDL Number:
MFCD00081152
MOL File:
3453-33-6.mol
MSDS File:
SDS
Last updated:2024-04-16 13:12:53

6-Methoxy-2-naphthaldehyde Properties

Melting point 81-84 °C(lit.)
Boiling point 196 °C / 10mmHg
Density 1.169±0.06 g/cm3(Predicted)
vapor pressure 0.022Pa at 25℃
storage temp. under inert gas (nitrogen or Argon) at 2-8°C
solubility Chloroform (Slightly), Methanol (Slightly, Sonicated)
form powder to crystal
color White to Light yellow to Light orange
Water Solubility 150.1mg/L at 25℃
Sensitive Air Sensitive
BRN 1945989
LogP 2.97 at 25℃
CAS DataBase Reference 3453-33-6(CAS DataBase Reference)
FDA UNII 9244L5L5ZY

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H315-H319-H335
Precautionary statements  P261-P264-P271-P280-P302+P352-P305+P351+P338
Hazard Codes  Xi
Risk Statements  36/37/38
Safety Statements  26-36-24/25-37/39
WGK Germany  3
HazardClass  IRRITANT
HS Code  29124990
NFPA 704
0
0 0

6-Methoxy-2-naphthaldehyde price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 533084 6-Methoxy-2-naphthaldehyde 98% 3453-33-6 5g $67.5 2024-03-01 Buy
TCI Chemical M1090 6-Methoxy-2-naphthaldehyde >97.0%(GC) 3453-33-6 5g $41 2024-03-01 Buy
TCI Chemical M1090 6-Methoxy-2-naphthaldehyde >97.0%(GC) 3453-33-6 25g $113 2024-03-01 Buy
Alfa Aesar B23943 6-Methoxy-2-naphthaldehyde, 99% 3453-33-6 5g $40.65 2024-03-01 Buy
Alfa Aesar B23943 6-Methoxy-2-naphthaldehyde, 99% 3453-33-6 25g $133.65 2024-03-01 Buy
Product number Packaging Price Buy
533084 5g $67.5 Buy
M1090 5g $41 Buy
M1090 25g $113 Buy
B23943 5g $40.65 Buy
B23943 25g $133.65 Buy

6-Methoxy-2-naphthaldehyde Chemical Properties,Uses,Production

Chemical Properties

yellow to beige-yellow crystals or crystalline

Uses

6-Methoxy-2-naphthaldehyde may be used in the preparation of the following 4-(6-methoxy-2-naphthyl)butan-2-one related compounds:

  • 4-(6-methoxy-2-naphthyl)but-3-en-2-one
  • 4-(6-methoxy-2-naphthyl)-3-methylbutan-2-one
  • 5-(6-methoxy-2-naphthyl)pentan-3-one

It may also be used in the synthesis of the following chalcone derivatives:
  • (2E)-1-(2-hydroxyphenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
  • (2E)-1-(2-chloropyridin-4-yl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one
  • (2E)-3-(6-methoxy-2-naphthyl)-1-pyridin-4-ylprop-2-en-1-one
  • (2E)-1-(2,4-dichlorophenyl)-3-(6-methoxy-2-naphthyl)prop-2-en-1-one

Uses

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluorescent substrates for inhibition studies relating to hypertension and vascular inflammation. It is also used as intermediate of Nabumetone.

Uses

6-Methoxy-2-naphthaldehyde is used as a diagnostic reagent in tumor studies involving aldehyde dehydrogenase enzymes. In addition it is used in organic synthesis reactions forming fluoresce nt substrates for inhibition studies relating to hypertension and vascular inflammation.

Synthesis Reference(s)

The Journal of Organic Chemistry, 53, p. 4587, 1988 DOI: 10.1021/jo00254a035

General Description

6-Methoxy-2-naphthaldehyde can be prepared by reacting 2-bromo 6-methoxy naphthalene with triethylorthoformate via Grignard reaction. Its crystals belong to the orthorhombic space group, P212121 and shows excellent NLO (non-linear optical) property.

Flammability and Explosibility

Not classified

Global( 368)Suppliers
Supplier Tel Email Country ProdList Advantage
Henan Fengda Chemical Co., Ltd
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Capot Chemical Co.,Ltd.
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18853181302 sale@chuangyingchem.com CHINA 5909 58
Chongqing Chemdad Co., Ltd
+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58

View Lastest Price from 6-Methoxy-2-naphthaldehyde manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
6-Methoxy-2-naphthaldehyde pictures 2024-04-16 6-Methoxy-2-naphthaldehyde
3453-33-6
US $5.00-0.10 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
6-Methoxy-2-naphthaldehyde pictures 2019-07-12 6-Methoxy-2-naphthaldehyde
3453-33-6
US $1.00 / KG 1KG 99% 100kg Career Henan Chemical Co

6-Methoxy-2-naphthaldehyde Spectrum

LABOTEST-BB LT01147524 ASINEX-REAG BAS 07663025 6-METHOXY-2-NAPHTHALDEHYDE TIMTEC-BB SBB010060 6-methoxy-2-naphthalaldehyde 6-methoxynaphthalene-2-carbaldehyde 6-Methoxy-2-Naphtaldehyde 6-Methoxy-2-naphthaldehyde,99% 6-METHOXY-2-NAPHTHALDEHYDENABUMETONE 6-Methoxy-2-naphthaldehyde ,98% 6-Methoxy-2-naphthalenecarbaldehyde 2-Naphthalenecarboxaldehyde, 6-Methoxy- 6-Methoxy-2-Naphthaidehyde 6-Methoxy -2-naphthalene forMaldehyde 6-Methoxy-2-naphthaldehyde 98% 6-Methoxy-2-naphthaldehyde> 2-ACETYL-6-METHOXYNAPHTHALENE 3900-45-6 6-Methoxy-naphthalen-2-carbaldehyde 6-Methoxy-2-napthaldehyde Mitotane Impurity 17 3453-33-6 CH3OC10H6CHO Organic Building Blocks ARYL ALDEHYDE Carbonyl Compounds C10 to C21 Building Blocks Aldehydes Building Blocks C10-C12 Carbonyl Compounds Chemical Synthesis Organic Building Blocks Aromatic Aldehydes & Derivatives (substituted) Aldehydes C10 to C21 Carbonyl Compounds 1 bc0001