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Calcium citrate

CAS No.
813-94-5
Chemical Name:
Calcium citrate
Synonyms
Tricalcium citrate;tribasiccalciumcitrate;Tricalcium Citrate anhydrous;citrical;acicontral;Calsium citrate;Calcium citrate;DICALCIUMCITRATE;CALCIUM CITRATE USP;TRICALCIUM DICITRATE
CBNumber:
CB7153589
Molecular Formula:
C12H10Ca3O14
Molecular Weight:
498.43
MDL Number:
MFCD00078618
MOL File:
813-94-5.mol
Last updated:2023-11-21 17:01:47

Calcium citrate Properties

solubility 0.1 M HCl: 0.01 M at 20 °C, clear, colorless
Odor at 100.00?%. odorless
Stability Stable. Incompatible with strong oxidizing agents.
LogP -1.721 (est)
FDA 21 CFR 184.1195; 582.1195; 582.5195; 582.6195
Substances Added to Food (formerly EAFUS) CALCIUM CITRATE
SCOGS (Select Committee on GRAS Substances) Calcium citrate
CAS DataBase Reference 813-94-5(CAS DataBase Reference)
FDA UNII 86117BWO7P
EPA Substance Registry System Tricalcium citrate (813-94-5)

SAFETY

Risk and Safety Statements

WGK Germany  1

Calcium citrate price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
AK Scientific 5928AF Calciumcitrate,anhydrous 813-94-5 100g $24 2021-12-16 Buy
Product number Packaging Price Buy
5928AF 100g $24 Buy

Calcium citrate Chemical Properties,Uses,Production

Description

Calcium citrate, a naturally occurring chemical in most plants and animals, is the calcium salt derived from citric acid. Calcium citrate is present in foods which have naturally occurring citric acid. Calcium citrate is used as a calcium supplement and may be used to treat conditions caused by low calcium levels such as bone loss (osteoporosis), weak bones (osteomalacia/rickets), decreased activity of the parathyroid gland (hypoparathyroidism), and a certain muscle disease (latent tetany). Calcium citrate may be chemopreventive for colon and other cancers. Calcium citrate is used as an ingredient in dietary supplements, and as a nutrient, sequestrant, buffer, antioxidant, firming agent, acidity regulator (in jams and jellies, soft drinks and wines), as a raising agent and an emulsifying salt. It is also used to improve the baking properties of flours and as a stabilizer.

References

  1. https://www.cancer.gov
  2. https://www.drugs.com
  3. https://www.webmd.com
  4. https://www.livestrong.com
  5. https://www.ams.usda.gov

Description

Calcium citrate is the calcium salt of citric acid. It is commonly used as a food additive (E333), usually as a preservative, but sometimes for flavor. In this sense, it is similar to sodium citrate. Calcium citrate is also used as a water softener because the citrate ions can chelate unwanted metal ions. Calcium citrate is also found in some dietary calcium supplements (e.g. Citracal). Calcium makes up 21% of calcium citrate by weight.

Chemical Properties

white powder or white to colourless crystals

Definition

ChEBI: Calcium citrate is an organic calcium salt composed of calcium cations and citrate anions in a 3:2 ratio. It has a role as a nutraceutical, a food additive, a food preservative and a flavouring agent. It contains a citrate(3-).

Production Methods

Calcium citrate is an intermediate in the isolation of citric acid from the fermentation process by which citric acid is produced industrially. The citric acid in the broth solution is neutralized by calcium hydroxide, precipitating insoluble calcium citrate. This is then filtered off from the rest of the broth and washed to give clean calcium citrate.
The calcium citrate thus produced may be sold as-is, or it may be converted to citric acid using dilute sulfuric acid.

Flammability and Explosibility

Non flammable

Pharmaceutical Applications

Calcium citrate is more easily absorbed (bioavailability is 2.5 times higher than calcium carbonate); it is easier to digest and less likely to cause constipation and gas than calcium carbonate. Calcium citrate can be taken without food and is more easily absorbed than calcium carbonate on an empty stomach. It is also believed that it contributes less to the formation of kidney stones. Calcium citrate consists of around 24% Ca2+, which means that 1000 mg calcium citrate contains around 240 mg Ca2+. The lower Ca2+ content together with the higher price makes it a more expensive treatment option compared to calcium carbonate, but its slightly different application field can justify this.

Biological Activity

In many individuals, bioavailability of calcium citrate is found to be equal to that of the cheaper calcium carbonate.However, alterations to the digestive tract may change how calcium is digested and absorbed. Unlike calcium carbonate, which is basic and neutralizes stomach acid, calcium citrate has no effect on stomach acid. Individuals who are sensitive to antacids or who have difficulty producing adequate stomach acid should choose calcium citrate over calcium carbonate for supplementation. According to recent research into calcium absorption after gastric bypass surgery , calcium citrate may have improved bioavailability over calcium carbonate in Rouxen- Y gastric bypass patients who are taking calcium citrate as a dietary supplement after surgery. This is mainly due to the changes related to where calcium absorption occurs in the digestive tract of these individuals.

Calcium citrate Preparation Products And Raw materials

Global( 280)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Dongdu Import and Export Co. LTD
+86-15333296769 +86-15333296769 manager@cndongdu.com China 71 58
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+86-518-85110578 +8618805133257 sales3257@jskolod.com China 132 60
Henan Tianfu Chemical Co.,Ltd.
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008657128800458; +8615858145714 fandachem@gmail.com China 9359 55
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+86-0371-86658258 sales@coreychem.com China 29919 58
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+86-19930503282 alice@crovellbio.com China 8823 58
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+8615821988213 info@longyupharma.com China 2530 58
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+86-023-61398051 +8613650506873 sales@chemdad.com China 39916 58

View Lastest Price from Calcium citrate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
calcium citrate pictures 2023-12-20 calcium citrate
813-94-5
US $1.85 / kg 1000kg 99% 5000 Tons/Year Hebei Dongdu Import and Export Co. LTD
Calcium citrate pictures 2023-06-15 Calcium citrate
813-94-5
US $8.50 / KG 1KG 99% 1 ton Baoji Guokang Bio-Technology Co., Ltd.
Calcium Citrate pictures 2023-02-23 Calcium Citrate
813-94-5
US $3.20 / kg 1kg 99.99% 20tons Hebei Duling International Trade Co. LTD
  • calcium citrate pictures
  • calcium citrate
    813-94-5
  • US $1.85 / kg
  • 99%
  • Hebei Dongdu Import and Export Co. LTD
  • Calcium citrate pictures
  • Calcium citrate
    813-94-5
  • US $8.50 / KG
  • 99%
  • Baoji Guokang Bio-Technology Co., Ltd.
  • Calcium Citrate pictures
  • Calcium Citrate
    813-94-5
  • US $3.20 / kg
  • 99.99%
  • Hebei Duling International Trade Co. LTD
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