4-Bromophenol
- CAS No.
- 106-41-2
- Chemical Name:
- 4-Bromophenol
- Synonyms
- P-BROMOPHENOL;Para Bromo Phenol;4-Bromphenol;Phenol, 4-bromo-;p-Bromphenol;4-BROMOPHENOL;BROMOPHENOL-4;P-Bromophenlo;4-bromo-pheno;p-bromo-pheno
- CBNumber:
- CB7181317
- Molecular Formula:
- C6H5BrO
- Molecular Weight:
- 173.01
- MDL Number:
- MFCD00002313
- MOL File:
- 106-41-2.mol
- MSDS File:
- SDS
| Melting point | 61-64 °C (lit.) |
|---|---|
| Boiling point | 235-236 °C (lit.) |
| Density | 1.84 |
| refractive index | 1.5085 (estimate) |
| Flash point | 235-238°C |
| storage temp. | room temp |
| solubility | 14g/l |
| form | Crystalline Solid |
| pka | 9.37(at 25℃) |
| color | Pinkish-brown |
| Water Solubility | It is insoluble in water. It is soluble in 5%ethanol. |
| λmax | 282nm(EtOH)(lit.) |
| Merck | 14,1428 |
| BRN | 1680024 |
| CAS DataBase Reference | 106-41-2(CAS DataBase Reference) |
| EWG's Food Scores | 1 |
| FDA UNII | LAO4J0183I |
| NIST Chemistry Reference | 4-Bromophenol(106-41-2) |
| EPA Substance Registry System | Phenol, 4-bromo- (106-41-2) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315 | |||||||||
| Precautionary statements | P264-P270-P280-P301+P312-P302+P352-P332+P313 | |||||||||
| Hazard Codes | Xn,Xi | |||||||||
| Risk Statements | 22-36/37/38-20/21/22 | |||||||||
| Safety Statements | 26-37/39-36 | |||||||||
| RIDADR | 2811 | |||||||||
| WGK Germany | 2 | |||||||||
| RTECS | SJ7960000 | |||||||||
| F | 8-10-23 | |||||||||
| Hazard Note | Irritant | |||||||||
| TSCA | Yes | |||||||||
| HazardClass | 6.1(b) | |||||||||
| PackingGroup | III | |||||||||
| HS Code | 29081000 | |||||||||
| Toxicity | mouse,LD50,intraperitoneal,411mg/kg (411mg/kg),Gigiena i Sanitariya. For English translation, see HYSAAV. Vol. 44(12), Pg. 19, 1979. | |||||||||
| NFPA 704 |
|
4-Bromophenol price More Price(38)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | B75808 | 4-Bromophenol 99% | 106-41-2 | 5g | $37.5 | 2024-03-01 | Buy |
| Sigma-Aldrich | B75808 | 4-Bromophenol 99% | 106-41-2 | 100g | $76.3 | 2024-03-01 | Buy |
| TCI Chemical | B0787 | 4-Bromophenol >98.0%(GC)(T) | 106-41-2 | 25g | $19 | 2024-03-01 | Buy |
| TCI Chemical | B0787 | 4-Bromophenol >98.0%(GC)(T) | 106-41-2 | 100g | $33 | 2024-03-01 | Buy |
| Alfa Aesar | A14873 | 4-Bromophenol, 99% | 106-41-2 | 100g | $61.8 | 2024-03-01 | Buy |
4-Bromophenol Chemical Properties,Uses,Production
Chemical Properties
4-Bromophenol is a pinkish-brown crystalline solid. four-sided biconical crystal precipitated from ether or chloroform. The melting point is 66.4 ℃, and a small amount of water can reduce the melting point a lot. Soluble in water, chloroform, easily soluble in ethanol, ether and glacial acetic acid, soluble in 7 parts of water.
Uses
4-Bromophenol is used as an intermediate in medicine grade. It is also used as a phenol that is used in Stille reactions. It is used in the intermediate of organic synthesis, flame retardant and pharmaceutical industry.
Application
4-Bromophenol is a phenolic derivative that It can used as a reagent in Stille reactions or Intermediates of Liquid Crystals.
Preparation
4-Bromophenol is synthesized by bromination of phenol. The bromine and carbon disulfide solution was added to the phenolic carbon disulfide solution, and the addition was started below 5°C, and the addition was completed under stirring for 2 hours. Phenol and bromine are approximately equimolar ingredients. Distill the reactant to remove carbon disulfide, and then conduct fractional distillation under reduced pressure to collect fractions at 145-150°C (3.32-3.99kPa) to obtain the product. Yield 80-84%.
Definition
ChEBI: 4-bromophenol is a bromophenol containing only hydroxy and bromo substituents that are para to one another. It has a role as a mouse metabolite, a persistent organic pollutant, a human xenobiotic metabolite, a rat metabolite, a human urinary metabolite and a marine metabolite.
Synthesis Reference(s)
Tetrahedron, 45, p. 7869, 1989 DOI: 10.1016/S0040-4020(01)85800-2
The Journal of Organic Chemistry, 23, p. 280, 1958 DOI: 10.1021/jo01096a033
Purification Methods
Crystallise the phenol from CHCl3, CCl4, pet ether (b 40-60o), or water and dry it at 70o under vacuum for 2hours. [Beilstein 6 IV 1043.]
4-Bromophenol Preparation Products And Raw materials
Raw materials
Preparation Products
1of5
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hebei Mojin Biotechnology Co., Ltd | +8613288715578 | sales@hbmojin.com | China | 12457 | 58 |
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Daken Advanced Materials Co.,Ltd | +86-371-66670886 | info@dakenam.com | China | 15928 | 58 |
| Henan Tianfu Chemical Co.,Ltd. | +86-0371-55170693 +86-19937530512 | info@tianfuchem.com | China | 21695 | 55 |
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Hebei Guanlang Biotechnology Co., Ltd. | +86-19930503282 | alice@crovellbio.com | China | 8823 | 58 |
| BTC Nantong Pharmaceuticals Technology Co.,Ltd | +8618068193575 | sales4@btcpharm.com | China | 254 | 58 |
| Hubei xin bonus chemical co. LTD | 86-13657291602 | linda@hubeijusheng.com | CHINA | 22968 | 58 |
View Lastest Price from 4-Bromophenol manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2024-02-26 | 4-Bromophenol
106-41-2
|
US $0.00-0.00 / kg | 1kg | 99% | Kgs | BTC Nantong Pharmaceuticals Technology Co.,Ltd | |
 |
2023-07-05 | 4-Bromophenol
106-41-2
|
US $0.00 / KG | 1KG | 99% | 50000KG/month | Hebei Mojin Biotechnology Co., Ltd | |
 |
2022-09-06 | 4-Bromophenol
106-41-2
|
US $1.10 / g | 1g | 99.00% | 100 Tons Min | Dideu Industries Group Limited |
-
- 4-Bromophenol
106-41-2
- US $0.00-0.00 / kg
- 99%
- BTC Nantong Pharmaceuticals Technology Co.,Ltd
-
- 4-Bromophenol
106-41-2
- US $0.00 / KG
- 99%
- Hebei Mojin Biotechnology Co., Ltd
-
- 4-Bromophenol
106-41-2
- US $1.10 / g
- 99.00%
- Dideu Industries Group Limited