(-)-3-Demethyldemecolcine

CAS No.
Chemical Name:
(-)-3-Demethyldemecolcine
Synonyms
3-Demethyldemecolcine;(-)-3-Demethyldemecolcine;(7S)-3-Hydroxy-1,2,10-trimethoxy-7α-(methylamino)-5,6-dihydrobenzo[a]heptalene-9(7H)-one;(S)-1-Methoxy-2-methyloxy-3-hydroxy-7-methylamino-10-methoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one
CBNumber:
CB72237489
Molecular Formula:
C20H23NO5
Molecular Weight:
0
MDL Number:
MOL File:
Mol file

(-)-3-Demethyldemecolcine Properties

Melting point 138°C

(-)-3-Demethyldemecolcine Chemical Properties,Uses,Production

Description

Colchicum autumnale, Gloriosa virescens and Littoria modesta contain this alkaloid in the corms and seeds. It forms colourless needles from EtOH and is laevorotatory having a specific rotation of [α]D - 1190 (CHCI3). It has been separated from the associated bases in these plants by column chromatography and countercurrent distribution techniques.

References

Maurer, Ohloff, Helv. Chim. Acta, 59, 1169 (1976)

(-)-3-Demethyldemecolcine Preparation Products And Raw materials

Raw materials

Preparation Products

(-)-3-Demethyldemecolcine (7S)-3-Hydroxy-1,2,10-trimethoxy-7α-(methylamino)-5,6-dihydrobenzo[a]heptalene-9(7H)-one (S)-1-Methoxy-2-methyloxy-3-hydroxy-7-methylamino-10-methoxy-6,7-dihydrobenzo[a]heptalen-9(5H)-one 3-Demethyldemecolcine