(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol
- CAS No.
- 58672-77-8
- Chemical Name:
- (20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol
- Synonyms
- Buxaminol B;(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol;Benzo[4,5]cyclohept[1,2-e]inden-2-ol, 9-(dimethylamino)-1,2,3,3a,4,7,8,9,10,10a,11,12,12a,12b-tetradecahydro-3a,10,10,12b-tetramethyl-3-[(1S)-1-(methylamino)ethyl]-, (2R,3S,3aR,9S,10aR,12aR,12bS)-
- CBNumber:
- CB72247972
- Molecular Formula:
- C27H46N2O
- Molecular Weight:
- 414.67
- MDL Number:
- MOL File:
- 58672-77-8.mol
(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol Chemical Properties,Uses,Production
Description
This alkaloid occurs in Buxus sernpervirens var. bullatus and forms colourless needles from Me2CO. It is dextrorotatory with a specific rotation of [α]D25 + 20° (c 0.59, MeOH) and gives an ultraviolet spectrum in EtOH with absorption maxima at 236, 246, 255 and 273 nm. Treatment with methyl iodide yields buxaminol A.
References
Bauerova, Paulik, Collect. Czech. Chern. Cornrnun., 40, 3055 (1975)
(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol Preparation Products And Raw materials
Raw materials
Preparation Products
(20S)-3β-(Dimethylamino)-4,4,14-trimethyl-20-(methylamino)-B(9a)-homo-19-nor-5α-pregna-9(11),9a-dien-16α-ol
Buxaminol B
Benzo[4,5]cyclohept[1,2-e]inden-2-ol, 9-(dimethylamino)-1,2,3,3a,4,7,8,9,10,10a,11,12,12a,12b-tetradecahydro-3a,10,10,12b-tetramethyl-3-[(1S)-1-(methylamino)ethyl]-, (2R,3S,3aR,9S,10aR,12aR,12bS)-
58672-77-8