ChemicalBook >> CAS DataBase List >>26,27-Dinorergost-5-ene-3β,24-diol
26,27-Dinorergost-5-ene-3β,24-diol
- CAS No.
- 35882-85-0
- Chemical Name:
- 26,27-Dinorergost-5-ene-3β,24-diol
- Synonyms
- SGE-201;SGE 201,SGE201;26,27-Dinorergost-5-ene-3β,24-diol;24,24-dimethyl-cholene-(5)-diol-(3β.24);26,27-Dinorergost-5-ene-3,24-diol, (3β)-;(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-5-methylhexan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
- CBNumber:
- CB72396838
- Molecular Formula:
- C26H44O2
- Molecular Weight:
- 388.63
- MDL Number:
- MFCD28386299
- MOL File:
- 35882-85-0.mol
Last updated:2023-06-06 08:28:36
26,27-Dinorergost-5-ene-3β,24-diol Chemical Properties,Uses,Production
Description
SGE-201 is a potent allosteric modulator of N-methyl-D-aspartate receptors. SGE-201 is an analogue of an endogenous oxysterol. bSGE-201 increased the actions of memantine and ketamine on phasic excitatory post-synaptic currents, but neither revealed underlying pharmacodynamic differences. SGE-201 accelerated the re-equilibration of blockers during voltage jumps. SGE-201 also unmasked differences among the blockers in neuronal networks - measured either by suppression of activity in multi-electrode arrays or by neuroprotection against a mild excitotoxic insult.
Synthesis of 26,27-Dinorergost-5-ene-3β,24-diol from 3β-Acetoxychola-5-ene-24-oic acid methyl ester and Methylmagnesium chloride
26,27-Dinorergost-5-ene-3β,24-diol Preparation Products And Raw materials
Raw materials
Preparation Products
26,27-Dinorergost-5-ene-3β,24-diol Suppliers
Global( 3)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| TargetMol Chemicals Inc. | +1-781-999-5354 +1-00000000000 | marketing@targetmol.com | United States | 19892 | 58 |
| SPIRO PHARMA | eric_feng1954@126.com | China | 9254 | 55 | |
| TargetMol Chemicals Inc. | 4008200310 | marketing@tsbiochem.com | China | 24017 | 58 |
| Supplier | Advantage |
|---|---|
| TargetMol Chemicals Inc. | 58 |
| SPIRO PHARMA | 55 |
| TargetMol Chemicals Inc. | 58 |
26,27-Dinorergost-5-ene-3β,24-diol
SGE-201
24,24-dimethyl-cholene-(5)-diol-(3β.24)
(3S,8S,9S,10R,13R,14S,17R)-17-[(2R)-5-hydroxy-5-methylhexan-2-yl]-10,13-dimethyl-2,3,4,7,8,9,11,12,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-3-ol
SGE 201,SGE201
26,27-Dinorergost-5-ene-3,24-diol, (3β)-
35882-85-0