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Hh-Ag 1.3

CAS No.
364590-63-6
Chemical Name:
Hh-Ag 1.3
Synonyms
Hh-Ag 1.3;Smoothened Agonist, HCl;Frizzled6 agonist SAG1.3;SAG . dihydrochloride (water soluble);3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide;Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-;3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride
CBNumber:
CB72524538
Molecular Formula:
C28H28ClN3OS
Molecular Weight:
490.06
MDL Number:
MFCD14636155
MOL File:
364590-63-6.mol
Last updated:2023-04-23 13:52:06

Hh-Ag 1.3 Properties

Boiling point 688.6±55.0 °C(Predicted)
Density 1.30±0.1 g/cm3(Predicted)
pka 10?+-.0.40(Predicted)
form White to off-white solid.
Water Solubility Soluble in water.
Sensitive Light Sensitive & Hygroscopic

Hh-Ag 1.3 price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 566660 Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem 364590-63-6 1mg $361 2024-03-01 Buy
Sigma-Aldrich 566660 Smoothened Agonist, SAG - CAS 364590-63-6 - Calbiochem 364590-63-6 5mg $1030 2024-03-01 Buy
Alfa Aesar J64726 Smoothened Agonist dihydrochloride dihydrate 364590-63-6 1mg $117 2021-12-16 Buy
Alfa Aesar J64726 Smoothened Agonist dihydrochloride dihydrate 364590-63-6 5mg $415 2021-12-16 Buy
Product number Packaging Price Buy
566660 1mg $361 Buy
566660 5mg $1030 Buy
J64726 1mg $117 Buy
J64726 5mg $415 Buy

Hh-Ag 1.3 Chemical Properties,Uses,Production

Uses

Smoothened Agonist, HCl (SAG), is a highly potent activator of Smo (smoothened). This chlorobenzothiophene compound is a hedgehog pathway agonist that interacts with the heptahelical domain of Smo. SAG is shown to act as an activator at low concentrations, but can inhibit Smo coupling at very high concentrations. The activating effects of SAG will counteract Cyclopamine or Cyclopamine-KAAD inhibition of Smo.

Hh-Ag 1.3 Preparation Products And Raw materials

Raw materials

Preparation Products

Hh-Ag 1.3 Suppliers

Global( 13)Suppliers
Supplier Tel Email Country ProdList Advantage
Finetech Industry Limited
+86-27-87465837 +8618971612321 info@finetechnology-ind.com China 9633 58
Aladdin Scientific
+1-833-552-7181 sales@aladdinsci.com United States 52927 58
Shanghai Witofly Chemical Co.,Ltd sales@witofly.com China 2867 52
ChemStrong Scientific Co.,Ltd 0755-0755-66853366 13670046396 sales@chem-strong.com China 17982 56
Finetech Industry Limited 027-87465837 19945049750 sales@finetechnology-ind.com China 9636 58
Aikon International Limited 025-58851090 13611564524 lwan@aikonchem.com China 15952 58
Nanjing crow LuNing pharmaceutical technology co., LTD 13382066392 CHINA 4880 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Nantong Hanfang Biotechnology Co. , Ltd. 3674309880 hanfangpharma@126.com China 30968 58
3-Chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]-benzo[b]thiophene-2-carboxamide Smoothened Agonist, HCl SAG . dihydrochloride (water soluble) Hh-Ag 1.3 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[(3-pyridin-4-ylphenyl)methyl]-1-benzothiophene-2-carboxamide,hydrate,dihydrochloride Benzo[b]thiophene-2-carboxamide, 3-chloro-N-[4-(methylamino)cyclohexyl]-N-[[3-(4-pyridinyl)phenyl]methyl]- Frizzled6 agonist SAG1.3 364590-63-6