TETANUS TOXIN C FRAGMENT
- CAS No.
- Chemical Name:
- TETANUS TOXIN C FRAGMENT
- Synonyms
- TTC;RTTC;TSTX-K-ALPHA-TTC;TETANUS TOXIN C FRAGMENT;TETANUS TOXIN C-FRAGMENT RECOMBINANT;TETANUS TOXIN, C-FRAGMENT, CLOSTRIDIUM TETANI;Tetanus toxin C fragment from Clostridium tetani
- CBNumber:
- CB7252844
- Molecular Formula:
- Molecular Weight:
- 0
- MDL Number:
- MFCD00166041
- MOL File:
- Mol file
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS06 |
|---|---|
| Signal word | Danger |
| Hazard statements | H300+H330-H311 |
| Precautionary statements | P280-P301+P310+P330-P302+P352+P312-P304+P340+P310 |
| Hazard Codes | T+ |
| Risk Statements | 26/27/28 |
| Safety Statements | 45-36/37-28 |
| RIDADR | UN 3462 6.1 / PGII |
| WGK Germany | 1 |
| RTECS | XW5807000 |
TETANUS TOXIN C FRAGMENT price More Price(4)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | T3694 | Tetanus toxin C fragment from Clostridium tetani | 10μg | $841 | 2024-03-01 | Buy | |
| Sigma-Aldrich | 582235 | Tetanus Toxin, C-Fragment, Clostridium tetani The C-terminal binding portion of the heavy chain of tetanus toxin. | 10μG | $943 | 2023-06-20 | Buy | |
| Cayman Chemical | 23222 | Tetanus Toxin C-Fragment from Clostridium tetani | 10μg | $723 | 2024-03-01 | Buy | |
| Usbiological | 215966 | Tetanus Toxin C-Fragment, Clostridium tetani | 10ug | $779 | 2021-12-16 | Buy |
TETANUS TOXIN C FRAGMENT Chemical Properties,Uses,Production
Uses
The C terminal binding portion of tetanus toxin is not toxic but is taken up by pre-synaptic nerve terminals and exhibits trans-synaptic retrograde transport in central neurons similar to that of tetanus toxin. It is used to map neuronal connections and to target proteins to neurons.
General Description
Tetanus toxin C fragment (TTC) is a non-toxic peptide, which is transported from peripheral axons into spinal motoneurons. It provides protection for motoneurons (MN) in the spinal cord in vivo. TTC regulates membrane binding, internalization and retrograde transport within MN. It initiates neurotrophin-regulated signaling pathways in a Trk receptor-dependent manner. TTC has neuroprotective property in primary cerebellar granule cell culture.
Biochem/physiol Actions
Tetanus toxin is a neurotoxin that comprises of a heavy and a light chain linked by disulfide bridges. This neurotoxin enters the cytoplasm and releases the light chain component that subsequently inhibits the release of neurotransmitters2. Studies have reported that the fragment C of tetanus toxin retains most of the determinants that interact with thyroid membranes, gangliosides and neural membranes3.
TETANUS TOXIN C FRAGMENT Preparation Products And Raw materials
Raw materials
Preparation Products
TETANUS TOXIN C FRAGMENT Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Sigma-Aldrich | 021-61415566 800-8193336 | orderCN@merckgroup.com | China | 51471 | 80 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 18818260767 | sales@chemegen.com | China | 11289 | 58 |
| Wuhan Xinzhecheng Technology Co., Ltd | 17720588118 | 2442693357@qq.com | China | 144 | 58 |
| Supplier | Advantage |
|---|---|
| Sigma-Aldrich | 80 |
| ChemeGen(Shanghai) Biotechnology Co.,Ltd. | 58 |
| Wuhan Xinzhecheng Technology Co., Ltd | 58 |