ChemicalBook >> CAS DataBase List >>Temephos

Temephos

CAS No.
3383-96-8
Chemical Name:
Temephos
Synonyms
temefos;ABATE;Abat;Difos;lypor;Ecopro;oms786;swebat;abaphos;Biothon
CBNumber:
CB7265792
Molecular Formula:
C16H20O6P2S3
Molecular Weight:
466.47
MDL Number:
MFCD00128034
MOL File:
3383-96-8.mol
Last updated:2023-05-18 11:30:47

Temephos Properties

Melting point 30-31°C
Boiling point 518.5±60.0 °C(Predicted)
Density 1.3200
vapor pressure 9.5×10-6Pa (20-25 °C)
storage temp. 2-8°C
solubility DMSO : ≥ 100 mg/mL (214.38 mM)
form solid
Water Solubility 0.003 g/100 mL
Merck 13,9214
BRN 1896901
InChI InChI=1S/C16H20O6P2S3/c1-17-23(25,18-2)21-13-5-9-15(10-6-13)27-16-11-7-14(8-12-16)22-24(26,19-3)20-4/h5-12H,1-4H3
InChIKey WWJZWCUNLNYYAU-UHFFFAOYSA-N
SMILES P(=S)(OC)(OC)OC1C=CC(SC2C=CC(OP(=S)(OC)OC)=CC=2)=CC=1
CAS DataBase Reference 3383-96-8(CAS DataBase Reference)
EWG's Food Scores 1
FDA UNII ONP3ME32DL
NIST Chemistry Reference Temefos(3383-96-8)
EPA Substance Registry System Temephos (3383-96-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS06,GHS09
Signal word  Danger
Hazard statements  H302-H311-H410
Precautionary statements  P264-P270-P273-P280-P301+P312-P302+P352+P312
Hazard Codes  Xn,N
Risk Statements  21/22-51/53
Safety Statements  22-37-61-60
RIDADR  UN 3077
WGK Germany  3
RTECS  TF6890000
HazardClass  6.1
PackingGroup  III
Toxicity LD50 in male, female rats (mg/kg): 8600, 13000 orally (Gaines)

Temephos price More Price(9)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 31526 Temephos PESTANAL?, analytical standard 3383-96-8 250mg $117 2024-03-01 Buy
TRC T017250 Temephos 3383-96-8 10g $1055 2021-12-16 Buy
AK Scientific O510 Temephos 3383-96-8 250mg $126 2021-12-16 Buy
Biorbyt Ltd orb595226 ABAT 3383-96-8 10μg $290.7 2021-12-16 Buy
Biorbyt Ltd orb528833 ABAT 3383-96-8 10μg $574.6 2021-12-16 Buy
Product number Packaging Price Buy
31526 250mg $117 Buy
T017250 10g $1055 Buy
O510 250mg $126 Buy
orb595226 10μg $290.7 Buy
orb528833 10μg $574.6 Buy

Temephos Chemical Properties,Uses,Production

Description

Abate is the trade name for Temephos, the known organophosphate larvicide. Abate is used to treat water infested with disease-carrying fleas and control mosquito, midge, and black fly larvae. Abate quickly controls mosquito and other insect populations because it kills insect larvae before they mature, and the residual activity of abate prevents insect populations. On decomposition, abate produces oxides of carbon, phosphorous, and sulphur. Exposures to abate in workplaces cause adverse health effects (refer to Temephos for details).

Chemical Properties

Temephos is a solid at room temperature and is composed of colorless crystals. As a liquid, it is brown and viscous. Temephos is a non-systemic insecticide. It is insoluble in water, hexane, and methyl cyclohexane, but soluble in common organic solvents. It is combustible and the liquid formulations contain organic solvents that may be flammable. Temophos decomposes on heating or burning, producing toxic fumes such as phosphorus oxides and sulfur oxides. Temephos reacts with strong acids and strong bases. The US EPA has grouped temephos as a GUP. Temephos is used for the control of mosquito, midge, and black fl y larvae. It is used in lakes, ponds, and wetlands. It may also be used to control fl eas on dogs and cats and to control lice on humans.

Uses

Temephos is used to control mosquito and black fly larvae in aqueous environments and as a human and veterinary ectoparasiticide.

Uses

Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects.

Definition

ChEBI: Temephos is an organic sulfide that is diphenyl sulfide in which the hydrogen at the para position of each of the phenyl groups has been replaced by a (dimethoxyphosphorothioyl)oxy group. It has a role as an EC 3.1.1.7 (acetylcholinesterase) inhibitor, an acaricide, an agrochemical and an ectoparasiticide. It is an organic thiophosphate, an organothiophosphate insecticide and an organic sulfide. It is functionally related to a 4,4'-thiodiphenol.

General Description

White crystalline solid or liquid. Boiling point 87°F. Used as an insecticide. Technical grade is a viscous brown liquid.

Reactivity Profile

Organothiophosphates are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

Cholinesterase inhibitor. Questionable carcinogen.

Health Hazard

Exposures to high concentrations of temephos for a prolonged period of time cause poisoning to occupational workers. The symptoms include, but are not limited to, nausea, salivation, headache, loss of muscle coordination, and diffi culty breathing. Workers exposed to a combination of temephos and malathion suffer potentiation of toxicity of temephos. Exposures to granules of temephos formulation may cause irritation. Prolonged and repeated skin contact may cause irritation. Inhalation may cause respiratory irritation and chemical pneumonities. There are no reports on the prolonged effects of temephos.

Health Hazard

Abate is less toxic in comparison to withmost other organophosphorus pesticides.Among the test animals, rats showedalmost 10 times greater resistance to thiscompound than did mice and rabbits.In humans, ingestion can cause nausea,vomiting, diarrhea, and convulsions. Intakeof large amounts can result in respiratoryfailure.
LD50 value, oral (rats): 8600 mg/kg.

Health Hazard

to avoid contamination of water, food, or feed, abate should be stored in a secure, dry,

Agricultural Uses

Insecticide, Larvicide: Temephos is one of the few organophosphates that is registered to control mosquito larvae. It is a non-systemic insecticide for use on wetlands, ponds, lakes and other moist areas to control mosquito, gnat, black fly, midge, pinkie and sandfly larvae. Banned for use in EU countries[ 115]. Registered for use in the U.S.

Trade name

27165®; ABAT®; ABATE®; ABATE® 1-SG; ABATE® 2-CG; ABATE® 4-E; ABATE® 5CG; ABATHION®; AI3-27165®; AC 52160®; AMERICAN CYANAMID AC-52,160®; AMERICAN CYANAMID CL-52160®; AMERICAN CYANAMID E. I.52,160®; BIOTHION®; BITHION®; CL 52160®; DIFENPHOS®; DIFENTHOS®; DIFOS®; DIPHOS®; ECOPRO®; ECOPRO® 1707; EI 52160®; NEPHIS®; NEPHIS® 1G; NIMITEX®; NIMITOX®

Safety Profile

Posion by ingestion Moderately toxic by intraperitoneal, subcutaneous, and skin contact routes. An experimental teratogen. A skin irritant. A cholinesterase inhibitor type of insecticide. When heated to decomposition it emits toxic fumes of POx and SOx. See also PARATHION,

Carcinogenicity

The EPA noted a chronic dog study (period of exposure not specified) in which significant inhibition of plasma and RBC cholinesterase occurred at dietary exposures equivalent to 12.5 mg/kg/day but not at 0.46 mg/kg/day .
No evidence of carcinogenicity or other treatment-related effects occurred in rats fed a diet that contained 0, 10, 100, or 300 ppm temephos (equivalent to about 0.5, 5.0, or 15 mg/kg/ day) for 2 years . The animals in the treated groups were exposed in utero from gestation day 12 through parturition to 100 ppm of the test material, and at weaning pups were randomly allocated to the three treatment groups and the treatment initiated.

Metabolic pathway

Temephos is comparatively stable to metabolic degradation in both animals and plants. The main pathway is via thiooxidation to the sulfoxide and through hydrolysis to yield 4,4’-thiodiphenol and its thiooxidised derivatives which are conjugated as glucosides in plants and as sulfate esters in rats. Oxidative desulfuration to temephos oxon is apparently a minor pathway.

storage

During use and handling of abate, occupational workers/applicators should wear long- sleeved shirts, long pants, shoes, and socks, chemical-resistant gloves, and protective eyewear, goggles, or safety glasses. Flaggers must wear chemical-resistant headgear and protective eyewear.

Degradation

Temephos is hydrolysed by strong acids and alkalis; its maximum stability is at pH 5-7 (PM). When a methanolic solution of temephos was exposed to sunlight it was rapidly decomposed resulting in the formation of at least eight photoproducts of which only temephos sulfoxide (2) and temephos sulfone (3) were identified. The sulfoxide was the major initial product but it was further photolysed to the sulfone (3) which was apparently refractory to further degradation suggesting that the other unidentified photoproducts arose directly from temephos or from the sulfoxide (2) (Rosen, 1972) (Scheme 1).

Toxicity evaluation

Temephos has a very low mammalian toxicity; acute oral LD50 for male and female rats is 4204 and >10,000 mg/kg, respectively. NOEL (2 yr) for rats is 300 mg/kg diet (15 mg/kg/d). Temephos administered orally to rats is eliminated in the feces and urine. The major elimination compound is unchanged temephos. Other urinary metabolites are sulfate ester conjugates of 4,4 -thiodiphenol, its sulfoxide, and sulfone.

Temephos Preparation Products And Raw materials

Raw materials

Preparation Products

Global( 132)Suppliers
Supplier Tel Email Country ProdList Advantage
Shanghai Qianyi New Material Co., Ltd.
+8618083322317 3391883138@qq.com China 878 58
Shanghai Daken Advanced Materials Co.,Ltd
+86-371-66670886 info@dakenam.com China 14764 58
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21700 55
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Xiamen AmoyChem Co., Ltd
+86-592-6051114 +8618959220845 sales@amoychem.com China 6387 58
CONIER CHEM AND PHARMA LIMITED
+8618523575427 sales@conier.com China 47465 58
career henan chemical co
+86-0371-86658258 15093356674; factory@coreychem.com China 29826 58
TargetMol Chemicals Inc.
+1-781-999-5354 +1-00000000000 marketing@targetmol.com United States 19892 58
Hefei TNJ Chemical Industry Co.,Ltd.
0551-65418671 sales@tnjchem.com China 34572 58
Xi'an MC Biotech, Co., Ltd.
029-89275612 +8618991951683 mcbio_sales@163.com China 2255 58

Related articles

  • Temephos:Uses,Health hazard,Disposal
  • Temephos is an organophosphate larvicide used to treat water infested with disease-carrying insects including mosquitoes, midg....
  • Apr 28,2023

View Lastest Price from Temephos manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
Temephos USP/EP/BP pictures 2021-07-10 Temephos USP/EP/BP
3383-96-8
US $1.10 / g 1g 99.9% 100 Tons Min Dideu Industries Group Limited
Temephos pictures 2020-01-08 Temephos
3383-96-8
US $3.00 / KG 1KG 98%min 200KG Career Henan Chemical Co
  • Temephos pictures
  • Temephos
    3383-96-8
  • US $3.00 / KG
  • 98%min
  • Career Henan Chemical Co
ABATE (TM) ABATHION(R) TEMEGUARD TEMEPHOS abaphos Abat Abate 1-SG, 2-CG, 4-E, 5CG abate4-e Abathion American cyanamid ac 52,160 American cyanamid cl-52160 American cyanamid E.I. 52,160 americancyanamidac52,160 americancyanamidcl-52160 americancyanamide.i.52,160 Biothion Biothon bis-p-(o,o-dimethylo-phenylphosphorothioate)sulfide Bithion CL 52160 cl52160 Difenphos Difenthos Difos Diphos (Pesticide) diphos(pesticide) diphos[pesticide] Ecopro ecopro1707 EI 52160 ei52160 ENT 27,165 ent27,165 Experimental Insecticide 52,160 Experimental Insecticide 52160 experimentalinsecticide52,160 experimentalinsecticide52160 lypor Nephis 1G nephis1g Nimitex Nimitox O,O'-(Thiodi-4,1-phenylene)bis(O,O-dimethyl phosphorothioate) O,O'-(Thiodi-4,1-phenylene)phosphorothioic acid O,O,O',O'-tetramethyl ester O,O'-(Thiodi-p-phenylene) O,O,O',O'-tetramethyl bis(phosphorothioate) o,o,o’,o’-tetramethylo,o’-thiodi-p-phenylenebis(phosphorothioate) o,o’-(thiodi-4,1-phenylene)bis(o,o-dimethylphosphorothioate) o,o’-(thiodi-4,1-phenylene)o,o,o’,o’-tetramethyldi(phosphorothioate) o,o’-(thiodi-4,1-phenylene)phosphorothioicacido,o,o’,o’-tetramethylester o,o’-(thiodi-p-phenylene)o,o,o’,o’-tetramethylbis(phosphorothioate) o,o’-(thiodi-p-phenylene)o,o,o’,o’-tetramethyldi(phosphorothioate) O,O-Dimethyl phosphorothioate O,O-diester with 4,4'-thiodiphenol Swebate tetramethyl-o,o’-thiodi-p-phenylenephosphorothioate Tetramethyl-O,O'-thiodi-p-phenylene phosphorothioate TEMEPHOS PESTANAL, 250 MG ABATE, 100MG, NEAT OOOOTETRAMETHYLOOTHIODIPARAPHENYLENEPHOSPHOROTHIOATE