ChemicalBook >> CAS DataBase List >>ML234
ML234
- CAS No.
- 1222800-79-4
- Chemical Name:
- ML234
- Synonyms
- ML243;ML324;ML234;CS-2198;ML324, ML-324;5-Pyrroledione;ML234 USP/EP/BP;NCGC00183808-01;ML-324;ML324;ML 324;ML324(CID-44143209)
- CBNumber:
- CB72744613
- Molecular Formula:
- C21H23N3O2
- Molecular Weight:
- 349.43
- MDL Number:
- MFCD28053518
- MOL File:
- 1222800-79-4.mol
Last updated:2023-05-18 11:31:19
| Melting point | >187oC (dec.) |
|---|---|
| Boiling point | 590.1±50.0 °C(Predicted) |
| Density | 1.188±0.06 g/cm3(Predicted) |
| storage temp. | Sealed in dry,2-8°C |
| solubility | DMSO: soluble10mg/mL, clear |
| pka | 4.71±0.40(Predicted) |
| form | powder |
| color | white to light brown |
| Stability | Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20° for up to 1 month. |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|---|---|
| Signal word | Warning |
| Hazard statements | H302 |
| Precautionary statements | P280-P305+P351+P338 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| WGK Germany | 3 |
ML234 price More Price(23)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | SML0741 | ML324 ≥98% (HPLC) | 1222800-79-4 | 5mg | $85.8 | 2024-03-01 | Buy |
| Sigma-Aldrich | SML0741 | ML324 ≥98% (HPLC) | 1222800-79-4 | 25mg | $430 | 2024-03-01 | Buy |
| Cayman Chemical | 17472 | ML-324 ≥95% | 1222800-79-4 | 1mg | $32 | 2024-03-01 | Buy |
| Cayman Chemical | 17472 | ML-324 ≥95% | 1222800-79-4 | 5mg | $70 | 2024-03-01 | Buy |
| Cayman Chemical | 17472 | ML-324 ≥95% | 1222800-79-4 | 10mg | $109 | 2024-03-01 | Buy |
ML234 Chemical Properties,Uses,Production
Description
ML324 (1222800-79-4) inhibits JMJD2 histone demethylases. Represses the expression of viral (HCMV and HSV-1) immediate early genes (IC50 ~ 10 μM) and abrogates infection. ML-324 represses the reactivation of HSV from the latent state in sensory neurons.1
Uses
ML324 is a JMJD2 demethylase inhibitor. It blocks the initiation of viral lytic infection and HSV-1 reactivation in the sensory ganglia of latently infected mice.
References
1) Liang?et al. (2013),?Targeting the JMJD2 histone demethylases to epigenetically control herpesvirus infection and reactivation from latency; Sci. Transl. Med.,?5?167ra5
ML234 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 94)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
| HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
| Dideu Industries Group Limited | +86-29-89586680 +86-15129568250 | 1026@dideu.com | China | 29271 | 58 |
| Zhejiang J&C Biological Technology Co.,Limited | +1-2135480471 +1-2135480471 | sales@sarms4muscle.com | China | 10523 | 58 |
| InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
| LEAP CHEM CO., LTD. | +86-852-30606658 | market18@leapchem.com | China | 24738 | 58 |
| Coresyn Pharmatech Co., Ltd. | +86-571-86626709 +86-18157142896 | cbc@coresyn.com | China | 9991 | 58 |
1222800-79-4(ML234)Related Search:
ML234
ML324
N-[3-(Dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)benzamide
NCGC00183808-01
ML324(CID-44143209)
CS-2198
ML-324;ML324;ML 324
Benzamide, N-[3-(dimethylamino)propyl]-4-(8-hydroxy-6-quinolinyl)-
ML234 USP/EP/BP
5-Pyrroledione
ML243
ML324, ML-324
1222800-79-4
Inhibitors