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NCT-501
- CAS No.
- 1802088-50-1
- Chemical Name:
- NCT-501
- Synonyms
- CS-2069;NCT-501;NCT-501 >=98% (HPLC);Inhibitor,Aldehyde Dehydrogenase (ALDH),inhibit,NCT-501,NCT 501;8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione;1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-
- CBNumber:
- CB73043300
- Molecular Formula:
- C21H32N6O3
- Molecular Weight:
- 416.52
- MDL Number:
- MFCD29472261
- MOL File:
- 1802088-50-1.mol
Last updated:2023-05-21 10:59:17
NCT-501 price More Price(17)
Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
---|---|---|---|---|---|---|---|
Cayman Chemical | 21162 | NCT-501 ≥98% | 1802088-50-1 | 1mg | $57 | 2024-03-01 | Buy |
Cayman Chemical | 21162 | NCT-501 ≥98% | 1802088-50-1 | 5mg | $233 | 2024-03-01 | Buy |
Cayman Chemical | 21162 | NCT-501 ≥98% | 1802088-50-1 | 10mg | $412 | 2024-03-01 | Buy |
Cayman Chemical | 21162 | NCT-501 ≥98% | 1802088-50-1 | 25mg | $887 | 2024-03-01 | Buy |
AK Scientific | 4502EC | 8-[[4-(Cyclopropanecarbonyl)piperazin-1-yl]methyl]-1,3-dimethyl-7-(3-methylbutyl)purine-2,6-dione | 1802088-50-1 | 25mg | $1086 | 2021-12-16 | Buy |
NCT-501 Chemical Properties,Uses,Production
Description
NCT-501 is a potent, reversible, theophylline-based inhibitor of ALDH1A1 (IC50 = 40 nM for the human form). It is selective for ALDH1A1 over other ALDH isozymes as well as other dehydrogenases. Pharmacokinetic studies indicate that NCT-501 has high bioavailability when delivered intraperitoneally, with rapid phase I modification in the liver.
References
yang s m, yasgar a, miller b, et al. discovery of nct-501, a potent and selective theophylline-based inhibitor of aldehyde dehydrogenase 1a1 (aldh1a1)[j]. journal of medicinal chemistry, 2015, 58(15): 5967-5978.
NCT-501 Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 75)Suppliers
Supplier | Tel | Country | ProdList | Advantage | |
---|---|---|---|---|---|
ATK CHEMICAL COMPANY LIMITED | +undefined-21-51877795 | ivan@atkchemical.com | China | 32480 | 60 |
HANGZHOU CLAP TECHNOLOGY CO.,LTD | 86-571-88216897,88216896 13588875226 | sales@hzclap.com | CHINA | 6313 | 58 |
InvivoChem | +1-708-310-1919 +1-13798911105 | sales@invivochem.cn | United States | 6393 | 58 |
TargetMol Chemicals Inc. | +1-781-999-5354 | support@targetmol.com | United States | 19973 | 58 |
Amadis Chemical Company Limited | 571-89925085 | sales@amadischem.com | China | 132020 | 58 |
Dalian Meilun Biotech Co., Ltd. | 0411-62910999 13889544652 | sales@meilune.com | China | 4648 | 58 |
Haoyuan Chemexpress Co., Ltd. | 021-58950125 | info@chemexpress.com | China | 7553 | 61 |
MedChemexpress LLC | 021-58955995 | sales@medchemexpress.cn | United States | 4863 | 58 |
Shanghai Lollane Biological Technology Co.,Ltd. | 021-52996696,15000506266 15000506266 | China | 4121 | 55 | |
Shanghai Beckham Medical Technology Co., Ltd | 13816613772 | huahero21@sina.com | China | 318 | 55 |
NCT-501
CS-2069
1H-Purine-2,6-dione, 8-[[4-(cyclopropylcarbonyl)-1-piperazinyl]methyl]-3,7-dihydro-1,3-dimethyl-7-(3-methylbutyl)-
NCT-501 >=98% (HPLC)
Inhibitor,Aldehyde Dehydrogenase (ALDH),inhibit,NCT-501,NCT 501
8-((4-(cyclopropanecarbonyl)piperazin-1-yl)methyl)-7-isopentyl-1,3-dimethyl-1H-purine-2,6(3H,7H)-dione
1802088-50-1