ChemicalBook >> CAS DataBase List >>4-Methylmorpholine N-oxide

4-Methylmorpholine N-oxide

4-Methylmorpholine N-oxide structure

CAS No.: 7529-22-8

Chemical Name:: 4-Methylmorpholine N-oxide

Synonyms: NMO;4-METHYLMORPHOLINE 4-OXIDE;N-Methylmorpholine oxide;Morpholine, 4-methyl-, 4-oxide;4-methyl-morpholin4-oxide;MMNO;NSC 73198;NSC 82153;ine N-oxide;nmo solution

CBNumber:: CB7305470

Molecular Formula:: C5H11NO2

Molecular Weight:: 117.15

MDL Number:: MFCD00005947

MOL File:: 7529-22-8.mol

MSDS File:: SDS

Last updated:2024-04-09 22:15:29

Request For Quotation

4-Methylmorpholine N-oxide Properties

Melting point	180-184 °C(lit.)
Boiling point	118-119°C
Density	1,14 g/cm³
vapor pressure	1.41hPa at 20℃
refractive index	n20/D 1.43
Flash point	118-119°C
storage temp.	2-8°C
solubility	DMSO (Soluble), Methanol (Slightly)
pka	4.93±0.20(Predicted)
form	Liquid
color	Clear colorless to yellow
PH	9.00 ( in neat)
Water Solubility	Soluble in water, methanol, ethanol, acetone, ethers and dimethylsulfoxide.
BRN	507437
Stability	Hygroscopic
LogP	-1.2 at 25℃
CAS DataBase Reference	7529-22-8(CAS DataBase Reference)
EWG's Food Scores	1
FDA UNII	ARC64PKJ0F
NIST Chemistry Reference	N-Methylmorpholine-N-oxide(7529-22-8)
EPA Substance Registry System	Morpholine, 4-methyl-, 4-oxide (7529-22-8)

SAFETY

Risk and Safety Statements

Symbol(GHS)

GHS02,GHS03,GHS08

Signal word

Danger

Hazard statements

H228-H272-H361f

Precautionary statements

P202-P210-P220-P240-P241-P308+P313

Hazard Codes

Risk Statements

36/37/38

Safety Statements

26-36/37

WGK Germany

TSCA

Yes

HS Code

29349990

NFPA 704

	1
2		0

4-Methylmorpholine N-oxide price More Price(47)

Manufacturer	Product number	Product description	CAS number	Packaging	Price	Updated	Buy
Sigma-Aldrich	8.14779	4-Methylmorpholine 4-oxide (50% solution in water) for synthesis	7529-22-8	250ML	$53.7	2024-03-01	Buy
Sigma-Aldrich	8.14779	4-Methylmorpholine 4-oxide (50% solution in water) for synthesis	7529-22-8	1L	$168	2024-03-01	Buy
Sigma-Aldrich	224286	4-Methylmorpholine N-oxide 97%	7529-22-8	5g	$55.3	2024-03-01	Buy
Sigma-Aldrich	224286	4-Methylmorpholine N-oxide 97%	7529-22-8	25g	$149	2024-03-01	Buy
TCI Chemical	M0981	4-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L)	7529-22-8	25mL	$18	2024-03-01	Buy

Product number	Packaging	Price	Buy
8.14779	250ML	$53.7	Buy
8.14779	1L	$168	Buy
224286	5g	$55.3	Buy
224286	25g	$149	Buy
M0981	25mL	$18	Buy

4-Methylmorpholine N-oxide Chemical Properties,Uses,Production

Chemical Properties

Clear colorless to yellow solution

Uses

4-Methylmorpholine N-oxide acts as a non-metallic catalyst for the cyanosilylation of ketones. It is also employed as a co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids. It serves as a solvent in the Lyocell process to produce tencel fiber. Further, it is used in the preparation of aldehydes from primary alcohols in the presence of tetrapropylammonium perruthenate.

Uses

Non-metallic catalyst for the cyanosilylation of ketones. Co-oxidant for Sharpless asymmetric dihydroxylation in ionic liquids.

Uses

4-Methylmorpholine N-Oxide is a metabolite of Morpholine (M723725). N-Methylmorpholine N-Oxide is commonly used to dissolve cellulose as well as in the dissolution of of scleroproteins.

Definition

ChEBI: N-methylmorpholine N-oxide is a morpholine N-oxide resulting from the oxidation of the amino group of N-methylmorpholine.

General Description

4-Methylmorpholine?N-oxide is an organic compound used as a co-oxidant along with OsO₄ and ruthenates in organic synthesis. In recent studies, it has been used as a catalyst in silylcyanation of aldehydes and ketones. Lyocell, a regenerated cellulose fiber, can be prepared using 4-methylmorpholine?N-oxide in an eco-friendly manner.

Flammability and Explosibility

Flammable

Purification Methods

When the oxide is dried for 2-3hours at high vacuum, it dehydrates. Add MeOH to the oxide and distil off the solvent under vacuum until the temperature is ca 95o. Then add Me2CO at reflux and cool to 20o. The crystals are filtered off, washed with Me2CO and dried. The degree of hydration may vary and may be important for the desired reactions. [van Rheenan et al. Tetrahedron Lett 1973 1076, Schneider & Hanze US Pat 2 769 823; see also Sharpless et al. Tetrahedron Lett 2503 1976.]

4-Methylmorpholine N-oxide synthesis

Synthesis of 4-Methylmorpholine N-oxide from 4-Methylmorpholine

4-Methylmorpholine N-oxide Preparation Products And Raw materials

Raw materials

Preparation Products

4-METHYL-2-OXO-2 H-CHROMENE-7-CARBALDEHYDE N-Boc-4-oxo-L-Proline methyl ester 4-Methylmorpholine N-oxide monohydrate 4-Bromo-2-nitroaniline N,N'-Dimorpholinomethane

BOC-4-OXO-L-PROLINE TERT-BUTYL ESTER PREGNANEDIONE

1of2

4-Methylmorpholine N-oxide Suppliers

Global( 438)Suppliers

Supplier	Tel	Email	Country	ProdList	Advantage
Fuxin Pharmaceutical	+86-021-021-50872116 +8613122107989	contact@fuxinpharm.com	China	10297	58
Hebei Mojin Biotechnology Co., Ltd	+8613288715578	sales@hbmojin.com	China	12457	58
Hebei Yanxi Chemical Co., Ltd.	+8617531190177	peter@yan-xi.com	China	5993	58
Henan Bao Enluo International TradeCo.，LTD	+86-17331933971 +86-17331933971	deasea125996@gmail.com	China	2503	58
Henan Fengda Chemical Co., Ltd	+86-371-86557731 +86-13613820652	info@fdachem.com	China	7613	58
Capot Chemical Co.,Ltd.	571-85586718 +8613336195806	sales@capotchem.com	China	29797	60
Hangzhou FandaChem Co.,Ltd.	008657128800458; +8615858145714	fandachem@gmail.com	China	9348	55
Shanghai Yingrui Biopharma Co., Ltd.	+86-21-33585366 - 03@	sales03@shyrchem.com	CHINA	738	60
career henan chemical co	+86-0371-86658258	sales@coreychem.com	China	29914	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	+86 18953170293	sales@sdzschem.com	China	2931	58

Supplier	Advantage
Fuxin Pharmaceutical	58
Hebei Mojin Biotechnology Co., Ltd	58
Hebei Yanxi Chemical Co., Ltd.	58
Henan Bao Enluo International TradeCo.，LTD	58
Henan Fengda Chemical Co., Ltd	58
Capot Chemical Co.,Ltd.	60
Hangzhou FandaChem Co.,Ltd.	55
Shanghai Yingrui Biopharma Co., Ltd.	60
career henan chemical co	58
SHANDONG ZHI SHANG CHEMICAL CO.LTD	58

View Lastest Price from 4-Methylmorpholine N-oxide manufacturers

Update time	Product	Price	Min. Order	Purity	Supply Ability	Manufacturer
2024-04-23	4-Methylmorpholine N-oxide 7529-22-8	US $5.00 / kg	1kg	≥99%	500mt/year	Jinan Finer Chemical Co., Ltd
2024-04-09	4-Methylmorpholine N-oxide 7529-22-8	US $8.00-0.80 / KG	1KG	99%	g-kg-tons, free sample is available	Henan Fengda Chemical Co., Ltd
2024-03-27	4-Methylmorpholine N-oxide 7529-22-8	US $0.00-0.00 / kg	1kg	99%	50000kg	Hebei Yibangte Import and Export Co. , Ltd.

4-Methylmorpholine N-oxide
7529-22-8
US $5.00 / kg
≥99%
Jinan Finer Chemical Co., Ltd

4-Methylmorpholine N-oxide
7529-22-8
US $8.00-0.80 / KG
99%
Henan Fengda Chemical Co., Ltd

4-Methylmorpholine N-oxide
7529-22-8
US $0.00-0.00 / kg
99%
Hebei Yibangte Import and Export Co. , Ltd.

4-Methylmorpholine N-oxide Spectrum

4-Methylmorpholine N-oxide(7529-22-8)¹HNMR 4-Methylmorpholine N-oxide(7529-22-8)¹³CNMR 4-Methylmorpholine N-oxide(7529-22-8)IR 4-Methylmorpholine N-oxide(7529-22-8)Raman

7529-22-8(4-Methylmorpholine N-oxide)Related Search:

Iron oxide Boron oxide Tribenuron methyl Methyl acrylate Tridemorph

Moroxydine ETHYLENE OXIDE Kresoxim-methyl Methanol Methylparaben

Moroxydine hydrochloride Iron oxide black 4-Methylmorpholine Rutile NITRIC OXIDE

N-Formylmorpholine 2,2,6,6-Tetramethylpiperidinooxy Methyl salicylate

1of4

4-Methyl-4-oxylatomorpholinium 4-Oxylato-4-methylmorpholine-4-ium N-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L) 4-Methylmorpholine N-oxide,NMO 4-Methylmorpholine N-oxide solution,NMO solution N-Methylmorpholine N-oxide - 50% w/w aqeous solution 4-MethylMorpholin-4-iuM-4-olate (50% in Water, ca. 4.8Mol/L) Morpholine,4-methyl-,4-oxide N-METHYLMORPHOLINE 4-OXIDE 4-METHYLMORPHOLINE N-OXIDE METHYL MORPHOLINE OXIDE 4-MethylMorpholine N-Oxide NSC 73198 NSC 82153 4-METHYLMORPHOLINE N-OXIDE, 50 WT. % SOL UTION IN WATER 4-MethylMorpholine N-oxide, 50 wt.% solution in H2O 4-MethylMorpholine N-oxide solution 50 wt. % in H2O N- MethylMorpholine oxide -N- NMMO solution OTHER DERIVATIVES OF PYRIDINES STERO NMMO 4-Methylmorpholine N-oxide, w/w aq. soln. 4-Methylmorpholine N-oxide solution, 50 wt. % in water 4-METHYLMORPHOLINE-4-OXIDE SOLUTION, ~50 % IN WATER N-MethylMorpholineOxide50%(Nmmo) 4-MethlMorpholine-N-Oxide99% N-Methyl morpholine-N-oxide, 60% w/w soln. in water N-MethylMorpholineOxide(NMMO) N-MethylmorpholineN-oxide,50%w/waq.soln. 4-methylmorpholine n-oxide solution nmo solution N-METHYLMORPHOLINE N-OXIDE: 50% W/W AQUEOUS SOLUTION 4-Methylmorpholine oxide 4-METHYLMORPHOLINE N-OXIDE 97% 4-methyl-4-oxidomorpholin-4-ium N-Methyl morpholine-N-oxide 4-methyl-4-oxidanidyl-morpholin-4-ium 4-METHYLMORPHOLINEN-OXIDE(WATERFREE) N-METHYL MORPHOLINE-N-OXIDE, 50% W/W SOLN. IN WATER 4-Methylmorpholine N-oxide, 50% w/w aq. soln. 4-Methylmorpholine N-Oxide (50% in Water, ca. 4.8mol/L) 4-Methylmorphine-4-oxide Morpholine, 4-methyl-, 4-oxide hydrate N-methyl-n-oxymorpholine 4-MethylmorpholineN-Oxide> N-Methyl-N-Oxomorph 4-Methylmorpholine N-oxide USP/EP/BP N- Methyl Morpholine Oxide -50 % & 60% [NMMO] ine N-oxide 4-methyl-morpholin4-oxide Morpholine, 4-methyl-, 4-oxide N-Methylmorpholine oxide NMO 4-METHYLMORPHOLINE 4-OXIDE MMNO 4-ethylmorpholineN-oxideMETHYLMORPHOLINE4-OXIDE 2,4-Dihydroxybenzoic acid 89-86-1 4-Methylmorpholine N-Oxide, 50wt.% in H2O