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4-Nitrophenyl chloroformate

CAS No.
7693-46-1
Chemical Name:
4-Nitrophenyl chloroformate
Synonyms
4-NITROPHENYL CARBONOCHLORIDATE;P-NITROPHENYL CHLOROFORMATE;PNPCF;Nitrophenyl chloroforMate;4-Nitrophenyl chloridocarbonate;4-NITROPHENYL CHLOROCARBONATE;PARA-NITROPHENYL CHLOROFORMATE;CHLOROFORMIC ACID P-NITROPHENYL ESTER;CARBONOCHLORIDIC ACID, 4-NITROPHENYL ESTER;p-Nitrophenyl c
CBNumber:
CB7348509
Molecular Formula:
C7H4ClNO4
Molecular Weight:
201.56
MDL Number:
MFCD00007321
MOL File:
7693-46-1.mol
MSDS File:
SDS
Last updated:2023-12-25 13:23:17

4-Nitrophenyl chloroformate Properties

Melting point 77-79 °C(lit.)
Boiling point 159-162 °C19 mm Hg(lit.)
Density 1.5719 (rough estimate)
refractive index 1.6000 (estimate)
Flash point >110°C
storage temp. 2-8°C
solubility Soluble in acetone, chloroform, acetone, toluene and benzene.
form isopropanol suspension
color White to yellow-beige
Water Solubility decomposes
Sensitive Lachrymatory
BRN 518127
Stability Stable. Incompatible with strong bases, acids. Combustible.
CAS DataBase Reference 7693-46-1(CAS DataBase Reference)
NIST Chemistry Reference Carbonochloridic acid, 4-nitrophenyl ester(7693-46-1)
EPA Substance Registry System Carbonochloridic acid, 4-nitrophenyl ester (7693-46-1)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictogramsGHS hazard pictograms
GHS05,GHS07
Signal word  Danger
Hazard statements  H314-H335
Precautionary statements  P260-P271-P280-P301+P330+P331-P303+P361+P353-P305+P351+P338
Hazard Codes  C,T,Xi,F
Risk Statements  34-36/37-23/24/25-41-36/37/38-11-67-36
Safety Statements  26-36/37/39-45-38-28A-36-16-27
RIDADR  UN 3261 8/PG 2
WGK Germany  3
19-21
Hazard Note  Toxic/Corrosive/Lachrymator
TSCA  Yes
HazardClass  8
PackingGroup  II
HS Code  29159020
NFPA 704
1
3 0

4-Nitrophenyl chloroformate price More Price(22)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich 160210 4-Nitrophenyl chloroformate 96% 7693-46-1 5g $75.4 2024-03-01 Buy
Sigma-Aldrich 160210 4-Nitrophenyl chloroformate 96% 7693-46-1 25g $227 2024-03-01 Buy
TCI Chemical C1400 4-Nitrophenyl Chloroformate >98.0%(T) 7693-46-1 25g $104 2024-03-01 Buy
TCI Chemical C1400 4-Nitrophenyl Chloroformate >98.0%(T) 7693-46-1 250g $646 2024-03-01 Buy
Alfa Aesar A18742 4-Nitrophenyl chloroformate, 97% 7693-46-1 5g $44.9 2024-03-01 Buy
Product number Packaging Price Buy
160210 5g $75.4 Buy
160210 25g $227 Buy
C1400 25g $104 Buy
C1400 250g $646 Buy
A18742 5g $44.9 Buy

4-Nitrophenyl chloroformate Chemical Properties,Uses,Production

Chemical Properties

Cream solid

Uses

4-Nitrophenyl chloroformate can be used:

  • As a reagent for the activation of amines, alcohols and thiols.
  • In the synthesis of 4-substituted phenyl derivatives of 1,2,4-triazolidindiones (urazoles).
  • In the solid-phase synthesis of 3-aryl-2,4-quinazolinedione derivatives with potent anti-cancer property.
  • In the preparation of poly(oxyethylene) modified dextrans.
  • To synthesize a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA.

Uses

4-Nitrophenyl chloroformate is used in the synthesis of poly(oxyethylene) modified dextrans. It is also used to prepare a cleavable, heterobifunctional cross-linker for reversible conjugation of amines to thiol-modified DNA. Further, it is used in the synthesis of mixed, activated carbonates, thiocarbonates and activated urethanes. In addition to this, it is used in the preparation of 4-nitrophenyl diazoacetate with diazomethane.

Uses

4-Nitrophenyl Chloroformate is an ester of chloroformic acid used in the immobilization of enzymes and other biomolecules.

Global( 495)Suppliers
Supplier Tel Email Country ProdList Advantage
Hebei Mojin Biotechnology Co., Ltd
+8613288715578 sales@hbmojin.com China 12456 58
Hebei Xinsheng New Material Technology Co., LTD.
+86-16632316109 xinshengkeji@xsmaterial.com China 1100 58
Henan Fengda Chemical Co., Ltd
+86-371-86557731 +86-13613820652 info@fdachem.com China 7845 58
Capot Chemical Co.,Ltd.
571-85586718 +8613336195806 sales@capotchem.com China 29797 60
Henan Tianfu Chemical Co.,Ltd.
+86-0371-55170693 +86-19937530512 info@tianfuchem.com China 21691 55
Hangzhou FandaChem Co.,Ltd.
008657128800458; +8615858145714 fandachem@gmail.com China 9348 55
career henan chemical co
+86-0371-86658258 sales@coreychem.com China 29914 58
Shenzhen Nexconn Pharmatechs Ltd
+86-755-89396905 +86-15013857715 admin@nexconn.com China 10248 58
Hubei Jusheng Technology Co.,Ltd.
18871490254 linda@hubeijusheng.com CHINA 28180 58
Hebei Guanlang Biotechnology Co., Ltd.
+86-19930503282 alice@crovellbio.com China 8823 58

View Lastest Price from 4-Nitrophenyl chloroformate manufacturers

Image Update time Product Price Min. Order Purity Supply Ability Manufacturer
4-Nitrophenyl chloroformate pictures 2023-12-26 4-Nitrophenyl chloroformate
7693-46-1
US $100.00-1.00 / KG 1KG 99% g-kg-tons, free sample is available Henan Fengda Chemical Co., Ltd
4-Nitrophenyl chloroformate pictures 2023-10-26 4-Nitrophenyl chloroformate
7693-46-1
US $25.00-15.00 / kg 1kg 99 20tons Hebei Xinsheng New Material Technology Co., LTD.
4-Nitrophenyl chloroformate pictures 2023-09-05 4-Nitrophenyl chloroformate
7693-46-1
US $100.00 / KG 1KG 99% 5000KG Hebei Mojin Biotechnology Co., Ltd
CHLOROFORMIC ACID 4-NITROPHENYL ESTER 4-NITROPHENYL CHLOROFORMATE 4-Nitrophenyl chloroforMate, 97% 25GR Formic acid, chloro-, p-nitrophenyl ester p-Nitrophenoxycarbonyl chloride ForMic acid, chloro-, p-nitrophenyl ester (6CI,7CI,8CI) 4-Nitrophenyl carbonochloridoate, 4-[(Chlorocarbonyl)oxy]nitrobenzene 4-Nitrophenyl Chloroformate >90% 4-Nitrophenyl chloroforMate 96% 4-Nitrophenyl ChloroforMate, 98.0% The nitrochlor forMate benzene ester p-Nitrophenyl chloroformate-activated Agarose (4-Nitrophenoxy)carbonyl chloride p-Nitrophenol chloroformate 4-Nitrophenyl chloroformate ,98% 4-Nitrophenylchloroformate,97% NITROPHENYL(4-) CHLOROFORMATE P-NITROPHENYL CHLOROCARBONATE 1-[(Chlorocarbonyl)oxy]-4-nitrobenzene 4-Nitrophenoxyformic acid chloride Chloridocarbonic acid 4-nitrophenyl Chloridocarbonic acid 4-nitrophenyl ester Chloroformic acid p-nitrophenyl 4-Nitrophenyl Chlorooate 4-Nitrophenyl carbonochloridate, 4-[(Chlorocarbonyl)oxy]nitrobenzene p-Nitrophenyl c 4-nitrophenyl carbonochloridat 4-Nitrophenyl chloroformate, 98%, for synthesis 4-Nitrophenyl Chloroformate > 4-NITROPENYLCHLOROFORMATE -Nitrophenyl chloroformate 4-Nitrophenyl chloroformate ISO 9001:2015 REACH 4-Nitrophenyl chloridocarbonate CARBONOCHLORIDIC ACID, 4-NITROPHENYL ESTER CHLOROFORMIC ACID P-NITROPHENYL ESTER 4-NITROPHENYL CHLOROCARBONATE Nitrophenyl chloroforMate 4-NITROPHENYL CARBONOCHLORIDATE PNPCF P-NITROPHENYL CHLOROFORMATE PARA-NITROPHENYL CHLOROFORMATE Ritonavir Intermediate 11 4-Nitrophenyl chloroformate (4-NPCF) Nintedanib Impurity 146 7693-46-1 7963-46-1 231-706-9 C8H4O4NI C7H4Cl1N1O4 ClCO2C6H4NO2 Coupling Synthetic Reagents Protection & Derivatization Reagents (for Synthesis) Active Esters/Additives Pharmaceutical intermediates Protection & Derivatization Reagents (for Synthesis) Synthetic Organic Chemistry blocks