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BARBITAL

CAS No.
57-44-3
Chemical Name:
BARBITAL
Synonyms
VERONAL;BARBITONE;Deba;Barbitone acid;DIETHYLBARBITURIC ACID;5,5-diethyl-1,3-diazinane-2,4,6-trione;Malona;Uronal;Diemal;Malonal
CBNumber:
CB7380141
Molecular Formula:
C8H12N2O3
Molecular Weight:
184.19
MDL Number:
MFCD00036212
MOL File:
57-44-3.mol
Last updated:2023-06-08 09:02:52

BARBITAL Properties

Melting point 188-192°C
Boiling point 318.14°C (rough estimate)
Density 1.2200
refractive index 1.4200 (estimate)
Flash point 11 °C
storage temp. 2-8°C
solubility DMSO (Slightly), Methanol (Slightly)
form Solid
pka 7.43(at 25℃)
color Faintly bitter crystals from H2O; polymorphicforms; triagonal crystals, monoclinic prisms, monoclinicneedles, and triclinic cryst
Water Solubility 7.149g/L(25 ºC)
Merck 13,965
EWG's Food Scores 1
FDA UNII 5WZ53ENE2P
ATC code N05CA04
EPA Substance Registry System 5,5-Diethylbarbituric acid (57-44-3)

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS07
Signal word  Warning
Hazard statements  H302
Precautionary statements  P264-P270-P301+P312-P330-P501
Hazard Codes  Xn,T,F
Risk Statements  22-39/23/24/25-23/24/25-11-63-40-20
Safety Statements  36-45-36/37-16-7
RIDADR  UN 1230 3/PG 2
WGK Germany  3
RTECS  CQ3500000
Toxicity LDLo orl-cat: 280 mg/kg PHREA7 19,472,39
DEA Controlled Substances CSCN: 2145
CSA SCH: Schedule IV
NARC: No
NFPA 704
3
0 0

BARBITAL price More Price(4)

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
Sigma-Aldrich B0300000 Barbital European Pharmacopoeia (EP) Reference Standard 57-44-3 B0300000 $152 2024-03-01 Buy
Cayman Chemical 22854 Barbital (CRM) 57-44-3 1mg $31 2023-06-20 Buy
Cayman Chemical 22012 Barbital 57-44-3 5mg $59 2023-06-20 Buy
Cayman Chemical 22012 Barbital 57-44-3 1mg $20 2023-06-20 Buy
Product number Packaging Price Buy
B0300000 B0300000 $152 Buy
22854 1mg $31 Buy
22012 5mg $59 Buy
22012 1mg $20 Buy

BARBITAL Chemical Properties,Uses,Production

Description

Barbital (CRM) (Item No. 22854) is a certified reference material categorized as a barbiturate. Barbital is regulated as a Schedule IV compound in the United States. Barbital (CRM) (Item No. 22854) is provided as a DEA exempt preparation. This product is intended for research and forensic applications.

Description

Barbital is an analytical reference material that is categorized as a barbiturate. It acts as an agonist at GABAA receptors to induce central nervous system depression. Formulations containing barbital have been used as a sedative to treat insomnia and seizures in human and veterinary medicine. Barbital is regulated as a Schedule IV compound in the United States. This product is intended for research and forensic applications.

Chemical Properties

White crystals or powder; bitter taste; odorless. Stable in air. Soluble in hot water, alcohol, ether, acetone, and ethyl acetate.

Uses

Prototype of the barbiturate hypnotics.

Definition

ChEBI: A member of the class of barbiturates, the structure of which is that of barbituric acid substituted at C-5 by two ethyl groups. Formerly used as a hypnotic (sleeping aid).

brand name

Dormileno;Escoderm;Hypnogene;Hypnox;Lidor;Megal;Plexonal;Somnytic tablets;Verinogen;Verodon;Veroletten;Verolitten;Veronigen.

World Health Organization (WHO)

Barbital is a long-acting barbiturate which is controlled under Schedule IV of the 1971 Convention on Psychotropic Substances. See WHO comment for barbiturates. (Reference: (UNCPS4) United Nations Convention on Psychotropic Substances (IV), , , 1971)

Safety Profile

Poison by ingestion, intravenous,intraperitoneal, and subcutaneous routes. Ingestion causespsychological effects in humans. Mutation data reported.When heated to decomposition it emits toxic fumes ofNOx. An hypnotic andsedative.

Purification Methods

Crystallise barbital from water or EtOH and dry it in a vacuum over P2O5. [Beilstein 24 III/IV 1901.]

BARBITAL Preparation Products And Raw materials

Raw materials

Preparation Products

barbital free acid crystalline--dea*schedule iv I barbital methanol solution Barbital(barbitone) BARBITAL FREE ACID CRYSTALLINE--DEASCHED ULE IV ITE BARBITAL, FOR ANALYTICAL PURPOSE (EXPORT CONTROL) BarbitonePh.Eur.+++ BARBITAL 99% GR BARBITAL,POWDER,PURIFIED Benzodiazepine ELISA Barbital solution 5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5,5-Diethylbarbituric acid, Barbitone, Veronal 10-Oxoisopiperitenone Barbital,5,5-Diethyl-2,4,6(1H,3H,5H)-pyrimidinetrione, 5,5-Diethylbarbituric acid, Barbitone, Veronal NSC 31352 kyselina5,5-diethylbarbiturova Malona Malonal Metharbital M (nor) Sedeval Uronal Veroletten Verolettin Vesperal 5,5-DIETHYL-2,4,6(1H,3H,5H)-PYRIMIDINETRIONE 5,5-DIETHYLBARBITURIC ACID LABOTEST-BB LT01148318 6(1h,3h,5h)-pyrimidinetrione,5,5-diethyl-4 Barbital(form2) Barbital(form3) Barbituric acid, 5,5-diethyl- Diemal Diethylbarbitone Dormonal Ethylbarbital Hypnogene Jpetab44,325,32 Kyselina 5,5-diethylbarbiturova Barbital (CIV), Powder, Purified DIETHYLMALONYLUREA BARBITAL 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl- 2,4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl- 4,6(1H,3H,5H)-Pyrimidinetrione,5,5-diethyl-2 5,5-Diethyl-2,4,6(1H,3H,5H)-phrimidinetri-one 5,5-diethyl-barbituricaci Barbital (CRM) 5,5-diethylpyrimidine-2,4,6(1H,3H,5H)-trione BARBITAL USP/EP/BP 5,5-diethyl-1,3-diazinane-2,4,6-trione Barbitone acid Deba VERONAL DIETHYLBARBITURIC ACID BARBITONE (S)-10-Oxoisopiperitenone Barbital (5,5 Diethyl Barbituric Acid) 57-44-3 C2H52CCONHCONHCO