ChemicalBook >> CAS DataBase List >>(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
- CAS No.
- 20445-31-2
- Chemical Name:
- (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid
- Synonyms
- Mosher;(R)-3,3,3-Trifluoro-2-Methoxy-2-phenylpropanoic acid;(+)-MTPA;(R)-(+)-MPTA;MOSHERS ACID;(+)-MOSHER'S ACID;(R)-(+)-Mosher acid;[Optical Resolving];(R)-(+)-MOSHER'S ACID;(R)-(+)-MTPA,(R)-(+)-Mosher'sacid
- CBNumber:
- CB7461358
- Molecular Formula:
- C10H9F3O3
- Molecular Weight:
- 234.17
- MDL Number:
- MFCD00004184
- MOL File:
- 20445-31-2.mol
- MSDS File:
- SDS
Last updated:2023-04-23 13:52:06
| Melting point | 46-49 °C(lit.) |
|---|---|
| Boiling point | 105-107 °C1 mm Hg(lit.) |
| alpha | D25 +68.5 ± 1.3° (c = 1.49 in CH3OH) |
| Density | 1.344 g/mL at 25 °C(lit.) |
| refractive index |
n |
| Flash point | >230 °F |
| storage temp. | 2-8°C |
| solubility | Soluble in methanol (50 mg/ 1 ml). |
| pka | 1.47±0.10(Predicted) |
| form | Crystalline Low Melting Solid |
| Specific Gravity | 1.344 |
| color | White |
| optical activity | [α]20/D +73±1°, c = 2% in methanol |
| Sensitive | Hygroscopic |
| Merck | 14,6280 |
| BRN | 2215440 |
| CAS DataBase Reference | 20445-31-2(CAS DataBase Reference) |
| FDA UNII | 27O5L9T1WM |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H315-H319-H335 | |||||||||
| Precautionary statements | P261-P264-P271-P280-P302+P352-P305+P351+P338 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 26-36 | |||||||||
| WGK Germany | 3 | |||||||||
| F | 3-10 | |||||||||
| Hazard Note | Irritant/Keep Cold | |||||||||
| HazardClass | IRRITANT, HYGROSCOPIC, KEEP COLD | |||||||||
| HS Code | 29189900 | |||||||||
| NFPA 704 |
|
(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid price More Price(28)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 155268 | (R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid 99% | 20445-31-2 | 1g | $292 | 2024-03-01 | Buy |
| Sigma-Aldrich | 155268 | (R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid 99% | 20445-31-2 | 5g | $532 | 2024-03-01 | Buy |
| TCI Chemical | M0831 | (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving] >98.0%(GC)(T) | 20445-31-2 | 1g | $197 | 2024-03-01 | Buy |
| TCI Chemical | M0831 | (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving] >98.0%(GC)(T) | 20445-31-2 | 5g | $747 | 2024-03-01 | Buy |
| Alfa Aesar | B22968 | (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99% | 20445-31-2 | 0.1g | $43.65 | 2024-03-01 | Buy |
(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Chemical Properties,Uses,Production
Chemical Properties
white crystalline low melting solid
Uses
(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid is widely used reagent for determination of optical purities of alcohols and amines by 1H or 19F NMR.
Uses
Mosher′s acid chloride is used as a dervatization agent for β-arylethylamines, enantiomeric alcohols, and enantiomeric amines. It is also a reagent used for the determination of enantiomeric purity and absolute configuration of alcohols and amines by NMR.
General Description
Mosher′s acid chloride is generally used as a chiral derivatizing agent. It is easily available in enantiomerically pure form. It can form diastereomers with both alcohols and amines.
Purification Methods
A likely impurity is phenylethylamine from the resolution. Dissolve the acid in Et2O/*benzene (3:1), wash with 0.5N H2SO4, then water, dry over magnesium sulfate, filter, evaporate and distil it. [Dale et al. J Org Chem 34 2543 1969, J Am Chem Soc 75 512 1973.]
(R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid Preparation Products And Raw materials
Global( 144)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Capot Chemical Co.,Ltd. | 571-85586718 +8613336195806 | sales@capotchem.com | China | 29797 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| CONIER CHEM AND PHARMA LIMITED | +8618523575427 | sales@conier.com | China | 47465 | 58 |
| Hubei Ipure Biology Co., Ltd | +8613367258412 | ada@ipurechemical.com | China | 10326 | 58 |
| Career Henan Chemica Co | +86-0371-86658258 15093356674; | laboratory@coreychem.com | China | 30255 | 58 |
| Hefei TNJ Chemical Industry Co.,Ltd. | 0551-65418671 | sales@tnjchem.com | China | 34572 | 58 |
| HONG KONG IPURE BIOLOGY CO.,LIMITED | 86 18062405514 18062405514 | ada@ipurechemical.com | CHINA | 3465 | 58 |
| Dayang Chem (Hangzhou) Co.,Ltd. | 571-88938639 +8617705817739 | info@dycnchem.com | CHINA | 52867 | 58 |
| ZHEJIANG JIUZHOU CHEM CO., LTD | +86-0576225566889 +86-13454675544 | admin@jiuzhou-chem.com；jamie@jiuzhou-chem.com；alice@jiuzhou-chem.com | China | 20000 | 58 |
| GIHI CHEMICALS CO.,LIMITED | +8618058761490 | info@gihichemicals.com | China | 49999 | 58 |
View Lastest Price from (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2021-07-02 | (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid 99%
20445-31-2
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
-
- (R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid 99%
20445-31-2
- US $15.00-10.00 / KG
- 99%+ HPLC
- Zhuozhou Wenxi import and Export Co., Ltd
20445-31-2((R)-(+)-alpha-Methoxy-alpha-trifluoromethylphenylacetic acid)Related Search:
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1of4
(R)-(+)-MTPA,(R)-(+)-Mosher'sacid
(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid, 99%(e.e.>99.5%)
(+)--Methoxy--(trifluoromethyl)phenylaceticacid(Moshersacid)
(r)-(+)-à-methoxy-à-(trifluoromethyl)phenylacetic acid
(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid 99% (99%ee)
(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylacetic acid (99%ee)
(R)-(+)-ɑ-Methoxy-ɑ-(trifluoromethyl)phenylacetic acid, 99%
(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic Acid [Optical Resolving]
(2R)-(+)-2-Methoxy-2-phenyl-3,3,3-trifluoropropanoic acid 99%
(R)-(+)-MTPA, (R)-(+)-Mosher's acid, (R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic acid
(R)-(+)-Mosher acid
(R)-3,3,3-Trifluoro-2-phenyl-2-methoxypropionic acid
[R,(+)]-3,3,3-Trifluoro-2-methoxy-2-phenylpropionic acid
[R,(+)]-α-Trifluoromethyl-α-methoxyphenylacetic acid
[R,(+)]-β,β,β-Trifluoro-α-methoxyhydratropic acid
(R)-(+)-alpha-Methoxy-alpha-(trifluoroMethyl)phenylacetic Acid
[Optical Resolving]
(R)-(+)-α-Methoxy-α-(trifluoroMethyl)phenylacetic Acid [Optical Resolving]
(R)-(+)-2-METHOXY-2-(TRIFLUOROMETHYL)PHENYLACETIC ACID
(R)-(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID
(R)-(+)-A-METHOXY-A-(TRIFLUOROMETHYL)PHENYLACETIC ACID
(R)-(+)-1-METHOXY-1-(TRIFLUOROMETHYL)PHENYLACETIC ACID
(R)-(+)-MPTA
(R)-(+)-MOSHER'S ACID
(+)-MOSHER'S ACID
MOSHERS ACID
(+)-MTPA
(+)-ALPHA-METHOXY-ALPHA-(TRIFLUOROMETHYL)PHENYLACETIC ACID
(+)-A-METHOXY-A-TRIFLUOROMETHYLPHENYLACETIC ACID
(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid
(R)-(+)-1-Methoxy-1-(trifluoromethyl)phenylaceticacid(ee)
(R)-(+)-α-Methoxy-α-(trifluoroMethyl)phenylacetic acid, ee: 99.5%
(R)-(+)-alpha-Methoxy-alpha-trifluoroMethylphenylacetic acid 99%
(2R)-3,3,3-trifluoro-2-methoxy-2-phenylpropanoic acid
(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic acid, 99%(e.e.>99.5%)
(R)-(+)--Methoxy--(trifluoromethyl)phenylacetic acid, 98%, ee: 99.5%
(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylaceticAcid[OpticalResolving]>
Benzeneacetic acid, α-methoxy-α-(trifluoromethyl)-, (αR)-
Benzeneacetic acid, a-methoxy-a-(trifluoromethyl)-, (aR)-
(R)-(+)-alpha-Methoxy-alpha-(trifluoromethyl)phenylacetic ac
(R)-(+)-α-Methoxy-α-(trifluoromethyl)phenylacetic Acid [Optical Resolving]
(R)-3,3,3-Trifluoro-2-Methoxy-2-phenylpropanoic acid
Mosher
(R)-(+)-α-Methoxy-α-trifluoromethylphenylacetic acid
(+)--methoxy--(trifluoromethyl)phenylacetic acid
(R)-2-Methoxy-2-phenyl-2-(trifluoromethyl)acetic Acid
20445-31-2
C6H5COCH3CF3CO2H
C6H5COCH3CF3COOH
C5H5COCH3CF3CO2H
C10H9F3O3
e.e. / Absolute Conefiguration Determination (NMR)
Enantiomer Excess & Absolute Conefiguration Determination
Chiral Resolving Reagents
Chiral Resolution Reagents
Derivatization Reagents
CARBOXYLIC ACID
Analytical Chromatography Product Catalog