ChemicalBook >> CAS DataBase List >>(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran

CAS No.
197706-51-7
Chemical Name:
(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran
Synonyms
Nebivolol Isomer-A;A-Isomer Nebivolol;Nebivolol Impurity 10;Nebivolol A Isomer (Nebivolol Imp-28);(S)-6-fluoro-2-((R)-oxiran-2-yl)chroman;(2S, 2’R)-6-Fluoro-2-(2’-oxiranyl)chromane;2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2S)-
CBNumber:
CB74748565
Molecular Formula:
C11H11FO2
Molecular Weight:
194.2
MDL Number:
MOL File:
197706-51-7.mol
Last updated:2023-05-04 15:15:55

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Properties

Boiling point 285.4℃ at 102kPa
Density 1.38g/cm3 at 20℃
vapor pressure 0.21-0.4Pa at 20-25℃
form Solid
LogP 2.5-3.2 at pH7

SAFETY

Risk and Safety Statements

Symbol(GHS)  GHS hazard pictograms
GHS09
Signal word  Warning
Hazard statements  H411

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC F595090 (2S,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane 197706-51-7 100mg $1540 2021-12-16 Buy
Product number Packaging Price Buy
F595090 100mg $1540 Buy

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Chemical Properties,Uses,Production

Uses

(2S,2’R)-6-Fluoro-2-(2’-oxiranyl)chromane is an intermediate to synthesize Nebivolol (rac, HCl salt, N387900) which is a β1-Adrenergic blocker.

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Preparation Products And Raw materials

Raw materials

Preparation Products

(+)-(S,R)-6-fluoro-3,4-dihydro-2-(2-oxiranyl)-2H-1-benzopyran Suppliers

Global( 24)Suppliers
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(S)-6-fluoro-2-((R)-oxiran-2-yl)chroman (2S, 2’R)-6-Fluoro-2-(2’-oxiranyl)chromane 2H-1-Benzopyran, 6-fluoro-3,4-dihydro-2-[(2R)-2-oxiranyl]-, (2S)- Nebivolol Impurity 10 A-Isomer Nebivolol Nebivolol A Isomer (Nebivolol Imp-28) Nebivolol Isomer-A 197706-51-7