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ChemicalBook >> CAS DataBase List >>42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Structure
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin structure
CAS No.
143030-02-8
Chemical Name:
42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin
Synonyms
Rapamycin Impurity 32;42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin;Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]-;Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I)
CBNumber:
CB75177306
Molecular Formula:
C57H93NO13Si
Molecular Weight:
1028.45
MDL Number:
MOL File:
143030-02-8.mol
Last updated:2023-04-23 13:52:06
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42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Properties

Boiling point 977.0±75.0 °C(Predicted)
Density 1.12±0.1 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Dichloromethane, Methanol
form Solid
pka 10.40±0.70(Predicted)
color White

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC D479400 42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin 143030-02-8 25mg $735 2021-12-16 Buy
Product number Packaging Price Buy
D479400 25mg $735 Buy

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Chemical Properties,Uses,Production

Uses

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin is an intermediate in the synthesis of 8-O-Methyl-rapamycin which is a derivative of Rapamycin (R124000), a triene macrolide antibiotic isolated from Streptomyces hygroscopicus. Name derived from the native word for Easter Island, Rapa’Nui. Used as an immunosuppressant; antirestenotic. Sirolimus (INN/USAN), also known as rapamycin, is an immunosuppressant drug used to prevent rejection in organ transplantation; it is especially useful in kidney transplants.

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Preparation Products And Raw materials

Raw materials

Preparation Products

42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Suppliers

Global( 8)Suppliers
Supplier Tel Email Country ProdList Advantage
Nanning Saifir Biotechnology Co., Ltd. 18877121284 1309367106@qq.com China 296 58
Shandong Wadesen Biotechnology Co. LTD 0531-88723173 18596073690 1047208234@qq.com China 3553 58
Hubei Xinyang Medical Technology Co., Ltd 15347293736 15347293736 2853117764@qq.com China 8695 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Wuhan Acumen Bio-Technology Co.,ltd 027-027-16602739303 16602739303 673003916@qq.com China 2887 58
guoyungurui 18162595016 3287908757@qq.com China 10012 58
United States Biological -- sales@advtechind.com United States 6106 58
Supplier Advantage
Nanning Saifir Biotechnology Co., Ltd. 58
Shandong Wadesen Biotechnology Co. LTD 58
Hubei Xinyang Medical Technology Co., Ltd 58
Energy Chemical 58
Wuhan Acumen Bio-Technology Co.,ltd 58
guoyungurui 58
United States Biological 58

143030-02-8(42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin)Related Search:

Everolimus 2-Piperidinecarboxylic acid, 1-[[(2R,3R,6S)-6-[(2S,3E,5E,7E,9S,11R)-2,13-dimethoxy-3,9,11-trimethyl-12-oxo-3,5,7-tridecatrienyl]tetrahydro-2-hydroxy-3-methyl-2H-pyran-2-yl]oxoacetyl]-, (1S,4R,5E)-1-[(1R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl]-4,6-dimethyl-3,7-dioxo-5-heptenyl es... Everolimus EP Impurity E USDOYNAPNXMXOE-SPSCNLKESA-N Everolimus Impurity 1
23,27-Epoxy(7E,15E,17E,19E)-3H-pyrido[2,1-c][1,4]oxaazacyclohentriacontine-1,5,11,28,29(4H,6H,31H)-pentone, 9,10,12,13,14,21,22,23,24,25,26,27,32,33,34,34a-hexadecahydro-9,27-dihydroxy-3-[(1R)-2-[(1S,3R,4R)-4-(2-hydroxyethoxy)-3-methoxycyclohexyl]-1-methylethyl]-10,21-dimethoxy-6,8,12,14,20,26-hexam... Everolimus Related Compound 3 EveroliMus-d4 Everolimus Related Compound 2 Rapamycin, 32-O-demethyl-
Seco Rapamycin Everolimus Hydrolized Impurity 28-epirapamycin Everolimus Ring-Opening Impurity 2,6-di-tert-butyl-4-methylene-2,5-cyclohexadienone

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42-O-[(1,1-Dimethylethyl)dimethylsilyl]rapamycin Rapamycin Impurity 32 Rapamycin, 42-O-[(1,1-dimethylethyl)dimethylsilyl]- Clobetasone Butyrate Impurity 9 (Clobetasone Butyrate EP Impurity I) 143030-02-8