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Methotrexate α-tert-Butyl Ester

Methotrexate α-tert-Butyl Ester Structure
Methotrexate α-tert-Butyl Ester structure
CAS No.
79640-70-3
Chemical Name:
Methotrexate α-tert-Butyl Ester
Synonyms
Methotrexate Impurity 8;Methotrexate α-tert-Butyl Ester;Methotrexate a-tert-Butyl Ester;Methotrexate α-tert-Butyl Ester;(S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid;L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) ester
CBNumber:
CB76091801
Molecular Formula:
C24H30N8O5
Molecular Weight:
510.55
MDL Number:
MFCD32868559
MOL File:
79640-70-3.mol
Last updated:2023-05-12 11:12:40
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Methotrexate α-tert-Butyl Ester Properties

Melting point >211°C (dec.)
Density 1.377±0.06 g/cm3(Predicted)
storage temp. -20°C Freezer
solubility Aqueous Base (Slightly), DMSO (Slightly), Methanol (Slightly, Heated)
form Solid
pka 4.43±0.10(Predicted)
color Pale Yellow to Orange

Methotrexate α-tert-Butyl Ester price

Manufacturer Product number Product description CAS number Packaging Price Updated Buy
TRC M260750 Methotrexateα-tert-ButylEster 79640-70-3 10mg $95 2021-12-16 Buy
TRC M260750 Methotrexateα-tert-ButylEster 79640-70-3 25mg $205 2021-12-16 Buy
TRC M260750 Methotrexateα-tert-ButylEster 79640-70-3 100mg $650 2021-12-16 Buy
Product number Packaging Price Buy
M260750 10mg $95 Buy
M260750 25mg $205 Buy
M260750 100mg $650 Buy

Methotrexate α-tert-Butyl Ester Chemical Properties,Uses,Production

Uses

Methotrexate α-tert-Butyl Ester is an intermediate to the synthesis of folic acid antagonist Methotrexate (M260675) used in the study of membrane-associated folate transporters from L1210 cells.

Methotrexate α-tert-Butyl Ester synthesis

45120-30-7
19741-14-1
79640-70-3
Synthesis of Methotrexate α-tert-Butyl Ester from L-Glutamic acid α-tert·butyl ester and 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID

Methotrexate α-tert-Butyl Ester Preparation Products And Raw materials

Raw materials

H-Glu(OMe)-OtBu 4-[N-(2,4-DIAMINO-6-PTERIDINYLMETHYL)-N-METHYLAMINO] BENZOIC ACID L-Glutamic acid α-tert·butyl ester

Preparation Products

Methotrexate α-tert-Butyl Ester Suppliers

Global( 17)Suppliers
Supplier Tel Email Country ProdList Advantage
Nantong QuanYi Biotechnology Co., Ltd 0513-66337626 18051384581 sales@chemhifuture.com China 4030 58
ChemShuttle, Inc. 0510-83588313-802 18800520310; sales@chemshuttle.com China 3062 62
Shanghai GL Peptide Ltd. +86-21-61263310; 13764994101 13764994101 fisherwang@glschina.com China 8457 55
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 18892239720 psaitong@jm-bio.com China 12308 58
Energy Chemical 021-58432009 400-005-6266 marketing@energy-chemical.com China 44941 58
Beijing Jin Ming Biotechnology Co., Ltd. 010-60605840 15801484223 psaitong@jm-bio.com China 29834 58
Tianjin shanhaijing medicine technology co., ltd 19129375004 15321929114 yangtzechem@163.com China 494 58
Shanghai Tachizaki Biomedical Research Center 18014399201 sales@chemlab-tachizaki.com China 2488 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 13720134139 13720134139 orders@jknbiochem.com China 4955 58
Henan Vcommend Consultrading Co., Ltd. 13393721940 sales@vcommend.com China 9773 58
Supplier Advantage
Nantong QuanYi Biotechnology Co., Ltd 58
ChemShuttle, Inc. 62
Shanghai GL Peptide Ltd. 55
Beijing Jin Ming Biotechnology Co., Ltd. 58
Energy Chemical 58
Beijing Jin Ming Biotechnology Co., Ltd. 58
Tianjin shanhaijing medicine technology co., ltd 58
Shanghai Tachizaki Biomedical Research Center 58
Wuhan Jingkangen Biomedical Technology Co., Ltd 58
Henan Vcommend Consultrading Co., Ltd. 58
Methotrexate α-tert-Butyl Ester (S)-5-(tert-butoxy)-4-(4-(((2,4-diaminopteridin-6-yl)methyl)(methyl)amino)benzamido)-5-oxopentanoic acid L-Glutamic acid, N-[4-[[(2,4-diamino-6-pteridinyl)methyl]methylamino]benzoyl]-, 1-(1,1-dimethylethyl) ester Methotrexate a-tert-Butyl Ester Methotrexate α-tert-Butyl Ester Methotrexate Impurity 8 79640-70-3