Ginkgolic acid
- CAS No.
- 22910-60-7
- Chemical Name:
- Ginkgolic acid
- Synonyms
- C-17:1;C10794;Ginkgolic;Ginkgolicaci;Ginkgoic acid;C15:1)Ginkgol;GINKGOLIC ACID;ROMANICARDIC ACID;Phenolic acid C15:1;(15:1)-Anacardic acid
- CBNumber:
- CB7673186
- Molecular Formula:
- C22H34O3
- Molecular Weight:
- 346.5
- MDL Number:
- MFCD03093717
- MOL File:
- 22910-60-7.mol
- MSDS File:
- SDS
| Melting point | 45～48℃ |
|---|---|
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly), Methanol (Slightly) |
| form | White solid |
| Boiling point | 221-223 °C(Press: 4 Torr) |
| Density | 0.9148 g/cm3 |
| pka | 3.08±0.30(Predicted) |
| color | White to Off-White |
| InChIKey | YXHVCZZLWZYHSA-FPLPWBNLSA-N |
| LogP | 9.269 (est) |
| CAS DataBase Reference | 22910-60-7(CAS DataBase Reference) |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H317-H413 | |||||||||
| Precautionary statements | P261-P272-P273-P280-P302+P352-P333+P313 | |||||||||
| Hazard Codes | Xi | |||||||||
| Risk Statements | 36/37/38 | |||||||||
| Safety Statements | 22-24/25-26 | |||||||||
| WGK Germany | 3 | |||||||||
| HS Code | 29182900 | |||||||||
| NFPA 704 |
|
Ginkgolic acid price More Price(31)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | 5.08197 | InSolution Ginkgolic Acid (15:1) - CAS 22910-60-7 - Calbiochem | 22910-60-7 | 2mg | $225 | 2024-03-01 | Buy |
| Sigma-Aldrich | 345887 | Ginkgolic Acid (15:1) | 22910-60-7 | 5mg | $417 | 2024-03-01 | Buy |
| Sigma-Aldrich | 02580585 | Ginkgolic acid C15:1 primary reference standard | 22910-60-7 | 10mg | $1080 | 2024-03-01 | Buy |
| Cayman Chemical | 18422 | Ginkgolic Acid C15:1 ≥95% | 22910-60-7 | 1mg | $62 | 2024-03-01 | Buy |
| Cayman Chemical | 18422 | Ginkgolic Acid C15:1 ≥95% | 22910-60-7 | 5mg | $254 | 2024-03-01 | Buy |
Ginkgolic acid Chemical Properties,Uses,Production
Description
Ginkgolic acid is slightly toxic and is an allergen; for this reason, some sources suggest using only the standardized extract, which is standardized to the flavonoids and minimizes ginkgolic acid content.
Ginkgolic acid is active against the tubercle bacillus. Elsewhere, leaf extracts are used in peripheral arterial circulation problems like arteriosclerotic angiopathy, post-thrombotic syndrome, diabetic vasoconstriction with gangrene and angina, intermittent claudication，Raynaud's disease. Extracts are inhaled for ear, nose, and throat ailments like bronchitis and chronic rhinitis.
Extracts of the leaves and fruit of Ginkgo plants have long been used in traditional medicine and have multiple potential therapeutic applications, including ameliorating dementia. However, ginkgolic acids, 2-hydroxy-6-alkylbenzoic acids related to anacardic acids, may be deleterious components in these extracts. Ginkgolic acid C15:1 is a 2-hydroxy-6-alkylbenzoic acid in which the alkyl chain contains 15 carbons and is unsaturated at the 8 position. It inhibits SUMOylation in vitro (IC50 = 3 μM) and in cells without affecting protein ubiquitination. Ginkgolic acid C15:1 directly binds the SUMO-activating enzyme E1, blocking the formation of the E1-SUMO intermediate. Ginkgolic acid C15:1 also suppresses the development of pancreatic cancer xenografts in mice.
Uses
Ginkgolic acid C15:1 may be used as a reference standard in the quantitative determination of alkylphenols like ginkgolic acids in Ginkgolic extract using high performance liquid chromatography coupled with mass spectrometry(HPLC-MS).
Ginkgolic acid C15:1 may be used as an analytical reference standard for the quantification of the analyte in Ginkgo biloba plant extracts, and dietary supplements using chromatography techniques.
Definition
ChEBI:Ginkgoic acid is a hydroxybenzoic acid. It derives from a salicylic acid.
General Description
Ginkgolic acid C15:1 is an alkylphenol belonging to the class of ginkgolic acids isolated from Ginkgo biloba leaves. It also shows strong allergenic properties, with carcinogenic and mutagenic activity.
Biochem/physiol Actions
Cell permeable: yes
Ginkgolic acid Preparation Products And Raw materials
Raw materials
1of2
Preparation Products
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Hangzhou FandaChem Co.,Ltd. | 008657128800458; +8615858145714 | fandachem@gmail.com | China | 9348 | 55 |
| Nanjing ChemLin Chemical Industry Co., Ltd. | 025-83697070 | product@chemlin.com.cn | CHINA | 3012 | 60 |
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| Chengdu GLP biotechnology Co Ltd | 028-87075086 13350802083 | scglp@glp-china.com | CHINA | 1824 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
| Alchem Pharmtech,Inc. | 8485655694 | sales@alchempharmtech.com | United States | 63711 | 58 |
| career henan chemical co | +86-0371-86658258 15093356674; | factory@coreychem.com | China | 29826 | 58 |
View Lastest Price from Ginkgolic acid manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Ginkgolic Acid
22910-60-7
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2022-12-29 | Ginkgolic acid
22910-60-7
|
US $8.80-7.90 / kg | 1kg | 99.99%HPLC;USP42 | 1000kg | Guangzhou Biocar Biotechnology Co.,Ltd. | |
 |
2022-02-24 | Ginkgolic acid
4554-49-0
|
US $1.00 / KG | 10g | 99% | 500kg | Xingtai Haoxun Import and Export Trade Co., Ltd. |
-
- Ginkgolic Acid
22910-60-7
- US $0.00 / mg
- ≥98%(HPLC)
- Shanghai Standard Technology Co., Ltd.
-
- Ginkgolic acid
22910-60-7
- US $8.80-7.90 / kg
- 99.99%HPLC;USP42
- Guangzhou Biocar Biotechnology Co.,Ltd.
-
- Ginkgolic acid
4554-49-0
- US $1.00 / KG
- 99%
- Xingtai Haoxun Import and Export Trade Co., Ltd.