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ORIENTIN
- CAS No.
- 28608-75-5
- Chemical Name:
- ORIENTIN
- Synonyms
- LUTEOLIN-8-C-GLUCOSIDE;Polygonin;Luteolin 8-C-β-D-glucopyranoside;lutexin;ORIENTIN;ORIENTINE;Aids026706;Aids-026706;ORIENTIN(P);ORIENTIN(SH)
- CBNumber:
- CB7710333
- Molecular Formula:
- C21H20O11
- Molecular Weight:
- 448.38
- MDL Number:
- MFCD00017432
- MOL File:
- 28608-75-5.mol
Last updated:2023-06-08 09:02:56
| Melting point | 260-285°C |
|---|---|
| Boiling point | 816.1±65.0 °C(Predicted) |
| Density | 1.759±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C(protect from light) |
| solubility | 1 M NaOH: soluble1mg/mL, clear, yellow-orange |
| pka | 6.24±0.40(Predicted) |
| form | powder |
| color | yellow |
| Stability | Hygroscopic |
| LogP | 1.580 (est) |
| FDA UNII | IAX93XCW6C |
SAFETY
Risk and Safety Statements
| Symbol(GHS) |  GHS07 |
|||||||||
|---|---|---|---|---|---|---|---|---|---|---|
| Signal word | Warning | |||||||||
| Hazard statements | H302-H315-H319-H335 | |||||||||
| Precautionary statements | P261-P280-P301+P312-P302+P352-P305+P351+P338 | |||||||||
| Safety Statements | 24/25 | |||||||||
| WGK Germany | 3 | |||||||||
| RTECS | DJ3009300 | |||||||||
| HS Code | 29389090 | |||||||||
| NFPA 704 |
|
ORIENTIN price More Price(37)
| Manufacturer | Product number | Product description | CAS number | Packaging | Price | Updated | Buy |
|---|---|---|---|---|---|---|---|
| Sigma-Aldrich | O9765 | Orientin ≥97% (HPLC) | 28608-75-5 | 1mg | $134 | 2024-03-01 | Buy |
| Sigma-Aldrich | 03810585 | Orientin primary pharmaceutical reference standard | 28608-75-5 | 10mg | $677 | 2024-03-01 | Buy |
| Cayman Chemical | 25143 | Orientin ≥95% | 28608-75-5 | 25mg | $61 | 2024-03-01 | Buy |
| Cayman Chemical | 25143 | Orientin ≥95% | 28608-75-5 | 50mg | $95 | 2024-03-01 | Buy |
| Sigma-Aldrich | O9765 | Orientin ≥97% (HPLC) | 28608-75-5 | 5mg | $496 | 2024-03-01 | Buy |
ORIENTIN Chemical Properties,Uses,Production
Description
Orientin is a flavone glycoside originally isolated from P. orientale that has diverse biological activities, including antioxidant, antibacterial, and anti-inflammatory properties. Orientin scavenges 2,2-diphenyl-1-picryl-hydrazyl (DPPH; ) radicals with an IC50 value of 316.21 μg/ml. It also decreases the cytopathic effects of parainfluenza type 3 virus with an IC50 value of 11.7 μg/ml and a cytotoxic concentration (CC50) value of 375 μg/ml in Hep-2 cells. Orientin (5-40 μM) inhibits LPS-induced barrier disruption, decreases the expression of toll-like receptor 4 (TLR4), phosphorylated p38, and NF-κB, and decreases TNF-α production and IL-6 secretion in a dose-dependent manner in human umbilical vein endothelial cells (HUVECs). It also prolongs survival in a mouse model of LPS-induced lethal endotoxemia when administered at a dose of 36 μg/animal 12 hours after LPS administration.
Chemical Properties
Yellow powder
Uses
Orientin is a flavone, a chemical flavonoid compound. Orientin have been investigated for its anti-oxidant, antihypertensive and antihyperlipidemic effects.
Definition
ChEBI: A C-glycosyl compound that is luteolin substituted by a beta-D-glucopyranosyl moiety at position 8.
ORIENTIN Preparation Products And Raw materials
Raw materials
Preparation Products
Global( 236)Suppliers
| Supplier | Tel | Country | ProdList | Advantage | |
|---|---|---|---|---|---|
| Shanghai Zheyan Biotech Co., Ltd. | 18017610038 | zheyansh@163.com | CHINA | 3620 | 58 |
| career henan chemical co | +86-0371-86658258 | sales@coreychem.com | China | 29914 | 58 |
| Chengdu Biopurify Phytochemicals Ltd. | +8618080483897 | sales@biopurify.com | China | 3424 | 58 |
| Nanjing Dolon Biotechnology Co.,Ltd. | 18905173768 | sales@dolonchem.com | CHINA | 2972 | 58 |
| Hubei Jusheng Technology Co.,Ltd. | 18871490254 | linda@hubeijusheng.com | CHINA | 28180 | 58 |
| Xi'an Kono chem co., Ltd., | 029-86107037 13289246953 | info@konochemical.com | China | 2995 | 58 |
| Shaanxi Pioneer Biotech Co., Ltd . | +8613259417953 | sales@pioneerbiotech.com | China | 3000 | 58 |
| BOC Sciences | +1-631-485-4226 | inquiry@bocsci.com | United States | 19553 | 58 |
| Chongqing Chemdad Co., Ltd | +86-023-61398051 +8613650506873 | sales@chemdad.com | China | 39916 | 58 |
| Shanghai Standard Technology Co., Ltd. | 18502101150 | ft-sales@nature-standard.com | CHINA | 1923 | 58 |
View Lastest Price from ORIENTIN manufacturers
| Image | Update time | Product | Price | Min. Order | Purity | Supply Ability | Manufacturer | |
|---|---|---|---|---|---|---|---|---|
 |
2023-02-24 | Orientin
28608-75-5
|
US $0.00 / mg | 5mg | ≥98%(HPLC) | 10 g | Shanghai Standard Technology Co., Ltd. | |
 |
2023-02-13 | Orientin
28608-75-5
|
US $90.00 / kg | 1kg | 99% | 80MT | Hebei baicao biology science and technology co., ltd | |
 |
2021-07-13 | Orientine
28608-75-5
|
US $15.00-10.00 / KG | 1KG | 99%+ HPLC | Monthly supply of 1 ton | Zhuozhou Wenxi import and Export Co., Ltd |
28608-75-5(ORIENTIN)Related Search:
4-N-HEXYLPHENOL
5-ETHYL-2-HYDROXY-BENZALDEHYDE
1-(2-Hydroxy-5-methylphenyl)ethanone
4-Phenylbutanol
ORIENTIN
4'-Hydroxy-3'-methylacetophenone
(S)-(-)-3-BENZYLOXY-1,2-PROPANEDIOL
1-(3-METHYLPHENYL)ETHANOL
(S)-(+)-1-Phenyl-1,2-ethanediol
(S)-(+)-4-PHENYL-2-BUTANOL
1of4
2-(3,4-Dihydroxyphenyl)-8-beta-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
ORIDONIN (RG)
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-.beta.-D-glucopyranosyl-5,7-dihydroxy-
Aids026706
Aids-026706
8-Glucosylluteolin
ORIENTIN
ORIENTINE
Orientin, froM PolygonuM orientale
Orientin,Lutexin
2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihydroxy-4h-1-benzopyra
4h-1-benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-beta-d-glucopyranosyl-5,7-dihy
luteolin8-glucoside
lutexin
orientin(flavone)
ORIENTIN(P)
ORIENTIN(SH)
ORIENTIN WITH HPLC
8-β-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
2-(3,4-Dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-4H-1-benzopyran-4-one
Orientin, 98%, from Polygonum orientale L.
Orientin, 98%, from Polygonum orientale
4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-8-β-D-glucopyranosyl-5,7-dihydroxy-
Luteolin 8-C-beta-D-Glucopyranoside
8-beta-D-Glucopyranosyl-3',4',5,7-tetrahydroxyflavone
ORIENTIN USP/EP/BP
2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-8-((2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)-4H-chromen-4-one
OrientinQ: What is
Orientin Q: What is the CAS Number of
Orientin Q: What is the storage condition of
Orientin Q: What are the applications of
Orientin
LUTEOLIN-8-C-GLUCOSIDE
Luteolin 8-C-β-D-glucopyranoside
Polygonin
4H-1-Benzopyran-4-one,2-(3,4-dihydroxyphenyl)-8-b-D-glucopyranosyl-5,7-dihydroxy-
28608-75-5
chemical reagent
pharmaceutical intermediate
phytochemical
reference standards from Chinese medicinal herbs (TCM).
standardized herbal extract
Aromatics, Glucuronides, Pharmaceuticals, Intermediates & Fine Chemicals